[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"compliance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:compliance":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,77,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100632984","changes-in-24-hour-activity-cycle-behaviors-during-a-time-restricted-eating-intervention-in-college-aged-women-100632984",false,"NCT07520786","Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women","DAWGS in Time-Restricted Eating and Activity Trends (DAWG-TREAT)","DAWG-TREAT","Inclusion Criteria:\n\n* Female undergraduate and graduate students\n* Enrolled full-time at University of Georgia\n* Aged 18-26 years\n\nExclusion Criteria:\n\n* having one of the following chronic diseases that maybe impacted by the diet changes: type 1 and 2 diabetes mellitus, cancer, cardiovascular diseases, hypertension, thyroid dysfunction, hepatic\u002Frenal impairment, inflammatory bowel disease and other gastrointestinal diseases,\n* report use of nicotine, thyroid medications, antidepressants, or anti-anxiety medications, melatonin\n* having clinically diagnosed sleep disorders\n* alcohol intake exceeds two drinks per day\n* clinically diagnosed or undiagnosed eating disorders\n* division-1 student athletes\n* pregnant or lactating or plan on getting pregnant within 6 months\n* report major ambulatory disorders,\n* recently (within the past two weeks) engaged in caloric restriction, timing-based dietary changes, weight loss regimens, or adhered to specialized diets such as ketogenic or paleo diets,\n* required to take medication with food, as these factors may interfere with sleep and physical activity outcomes or pose risks to participant health during restricted eating protocols. Students whose habitual eating time windows are \\\u003C10 hours will also not be eligible.",true,"FEMALE","18 Years","26 Years",{"count":22,"type":23},36,"ESTIMATED","INTERVENTIONAL",[26],"NA","Time-restricted Eating (TRE) is a dietary approach that limits food intake to 4 - 12-hour windows without intentionally altering diet quality. TRE has several benefits including modest reductions in body weight and fat mass, improved glucose control, and reduced inflammatory markers. While research supports the metabolic and weight related benefits of TRE, there is limited evidence of its effects on physical activity (PA), sedentary behavior (SB) and sleep - the core components of 24-hour Activity Cycle (24-HAC), which is a holistic framework that integrates the three health-related activities. TRE research has largely focused on clinical populations, leaving its feasibility and adherence in healthy younger adults understudied. Within this group, college students' misaligned circadian rhythms and unpredictable schedules may make adherence to TRE challenging, highlighting the need for research on its practicality in this group. These outcomes are also particularly important to investigate in women, considering that SB is more prevalent among college-aged women (69%) compared to men (46%). To address these issues, we will conduct a three-week intervention to study the effects of TRE on the 24-HAC outcomes. College aged women will be screened and enrolled, then assigned to either a control or TRE group. Participants in the TRE group will self-select the timing of their 8-hour eating window which they will maintain throughout the study (with compliance on at least six days per week needed to be considered adherent). The control group will receive a basic nutrition education at the start of the study and will have no restriction on eating times. 24 HAC behaviors will be measured continuously for one-week of baseline measurement and throughout the intervention by wrist-worn ActiGraph GT9X monitors. Participants will also record the timing of their first and last meal each day and receive periodic reminders to report their hunger and satiety ratings using visual analog scales.",[29,30,31,32,33],"Sleep Quality","Compliance","Physical Activity","Sedentary Behaviors","Sleep Duration",[35,36,37],"Time restricted eating","Sleep quality","24-Hour activity cycle","RECRUITING","2026-04-02",{"date":41,"type":42},"2026-04-09","ACTUAL",{"date":44,"type":42},"2026-02-01",{"date":46,"type":23},"2027-04",{"name":48,"class":49},"University of Georgia","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":19,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":24,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":50},"100616662","clinical-microbiological-and-compliance-outcomes-of-ai-based-toothbrushes-in-plaque-induced-gingivitis-100616662","NCT07308522","Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis","Clinical ,Microbiological and Compliance Outcomes of AI-based vs Standard Electric and Manual Toothbrushes in Adults With Plaque-Induced Gingivitis: A 6-Week Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants should be systemically healthy\n* 18 years old, with the presence of ≥ 20 teeth\n* Diagnosed with generalized plaque-induced gingivitis having \\>30% bleeding sites, with probing depths ≤3 mm and intact periodontium\n* Participants with at least secondary school education, who are able to read and understand basic English to follow the app-based toothbrush instructions\n\nExclusion Criteria:\n\n* Participants who using antibiotics or anti-inflammatory medication throughout the investigation or during the previous 3 months prior to the study.\n* Drug-induced gingival enlargement (phenytoin, cyclosporine, calciumchannel blockers).\n* Individuals with periodontitis and healthy periodontium.\n* Mouth breathers .\n* Individuals with severe dental crowding or malalignment that prevents proper toothbrushing.\n* Individuals with heavy calculus.\n* Individuals who smoke or alcoholism.\n* Pregnant, breastfeeding women or those using contraceptive tablets.\n* Individuals with orthodontic devices or removable dentures","ALL","35 Years",{"count":61,"type":23},33,[26],"Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.",[65,66,30],"Plaque Induced Gingivitis","Toothbrushing","NOT_YET_RECRUITING","2025-12-13",{"date":70,"type":42},"2025-12-29",{"date":72,"type":23},"2026-01-01",{"date":74,"type":23},"2026-06-30",{"name":76,"class":49},"University of Baghdad",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":24,"phases":88,"briefSummary":89,"conditions":90,"keywords":101,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":50},"100609100","pre-habilitation-within-eras-protocol-for-gynecologic-oncology-surgery-the-preeras-study-100609100","NCT07210164","Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study","Prehabilitation With Exercise and Immunonutrition (Ocoxin®) in the Perioperative Management of Gynecologic Malignancies Under ERAS Protocol.","Pre_ERAS","Inclusion Criteria:\n\n* Type of gynecological malignancy: endometrial cancer, ovarian cancer, cervical cancer, treated with laparotomy after the decision of the gynecological-oncology unit (positive opinion of the Multidisciplinary Tumor Board - MDT)\n* Patient age: 18 to 85 years\n* General condition of the patient: ASA score I-III\n* Consent to implement the accelerated recovery protocol - Enhanced recovery after surgery (ERAS)\n* Sufficient understanding of the Greek language\n* Provision of signed, after thorough information, consent to participate in the study\n\nExclusion Criteria:\n\n* Women with performance status: ECOG \\>2 and ASA score \\>III\n* Women who have not been informed and have given written consent","85 Years",{"count":87,"type":23},100,[26],"ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a quicker recovery. In gynecologic cancer surgeries, ERAS has been shown to help patients do better, have fewer problems, and leave the hospital sooner.\n\nA prehabilitation program, in combination with ERAS protocols, aims to optimize patients' physical and psychological condition prior to surgery for gynecological cancers. Interventions may include tailored exercise, nutritional support, respiratory training, and psychological preparation. By enhancing baseline fitness and resilience, prehabilitation improves the body's ability to tolerate surgical stress, reduces complications, and facilitates a faster, smoother recovery within the ERAS framework.",[91,30,92,93,94,95,96,97,98,99,100],"ERAS","Quality of Life (QOL)","Excercise","Immunonutrition","Post Operative Pain","Laparotomy Patients","Surgical Complication","Gynaecological Malignancies","Gynaecologic Cancer","Gynaecological Oncology",[102,91,103,94],"Prehabilitation","Gynecologic Cancers","2025-09-29",{"date":106,"type":42},"2025-10-07",{"date":108,"type":23},"2025-12-01",{"date":110,"type":23},"2029-12-30",{"name":112,"class":49},"Aristotle University Of Thessaloniki",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":58,"minAge":19,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":24,"phases":123,"briefSummary":124,"conditions":125,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":140},"100576153","combining-light-therapy-and-cpap-in-depression-100576153","NCT06781593","Combining Light Therapy and CPAP in Depression","Effects of Light Therapy on Compliance With Continuous Positive Airway Pressure in a Population of Depressed Patients Newly Fitted With Devices for Obstructive Sleep Apnea","LUCIOPRESS","Inclusion Criteria:\n\n* Adults consulting at the MICHEL JOUVET unit, CH Le Vinatier, Bron\n* Adults with a diagnosis of major depressive episode (DSM-V) and with a MADRS score ≥ 15\n* Adults with a diagnosis of OSAS on ventilatory polygraphy or polysomnography (AASM 2017 criteria) requiring CPAP.\n\nExclusion Criteria:\n\n* Refusal to participate.\n* Pregnant and breast-feeding women\n* Under guardianship or curatorship.\n* Unstable psychiatric or physical pathology (e.g., hypomania, high suicidal risk) considered incompatible with the study by the investigators.\n* Other psychiatric, neurologic or somatic conditions\n* Contraindication to light therapy: retinopathy, retinitis pigmentosa, diabetic retinopathy, macular degeneration, glaucoma, recent eye surgery (less than 3 months).\n\npatient wishing to choose a provider other than the protocol provider.\n\n* Patient wishing to choose a device other than SEFAM's S-BOX or a mask other than the nasal mask at the time of introduction.\n* Nasal obstruction.\n* Refusal to use actimetry, refusal to use light therapy, refusal to use CPAP.",{"count":122,"type":23},130,[26],"In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.",[126,127,128,30,129,130],"Major Depression","Sleep Architecture","Obstructive Sleep Apnea","Continuous Positive Airway Pressure (CPAP)","Light Therapy","2025-04-24",{"date":133,"type":42},"2025-04-29",{"date":135,"type":42},"2025-01-17",{"date":137,"type":23},"2027-10-30",{"name":139,"class":49},"Hôpital le Vinatier",2]