[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"complicationpostoperative\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:complicationpostoperative":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,39,67,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100594175","variability-and-post-op-aes-does-preoperative-cardiopulmonary-variability-assessment-identify-risk-of-postoperative-adverse-events-following-thoracic-surgery-100594175",false,"NCT07016022","Variability and Post-op AEs: Does Preoperative CardioPulmonary Variability Assessment Identify Risk of Postoperative Adverse Events Following Thoracic Surgery","CPVA","Inclusion Criteria:\n\n* Adult patient (≥18 years of age)\n* Patients undergoing major thoracic resection for lung, esophageal or gastric cancer or mediastinal tumour (at least lobectomy, pneumonectomy, esophagectomy, gastrectomy, or mediastinal tumour resection)\n\nExclusion Criteria:\n\n* Urgent\u002Femergent cases\n* Patients with pre-existing atrial fibrillation or arrhythmia (persistent\u002Fparoxysmal)\n* Patients that are pacemaker dependent\n* Patients unable to participate in preoperative testing protocol (CardioPulmonary Variability Assessment)\n* Patients that are pregnant","ALL","18 Years",{"count":19,"type":20},130,"ESTIMATED","OBSERVATIONAL","Major thoracic surgery is high risk as it carries a significant risk of postoperative Adverse Events (AEs), where patients experience complications and do not recover as expected. These AEs can increase the risk of mortality, hospital length of stay, as well as healthcare costs. The investigators' aim is to improve surgical safety by pioneering a marked advance in preoperative prediction of postoperative AEs that will enable individualized targeted perioperative pathways to prevent postoperative AEs. Given that illness and stress are associated with a loss in physiologic variability (e.g. heart and respiration rate), the investigators will use heart and lung variability assessments to improve prediction of postoperative AEs. Therefore, this study aims to assess the feasibility of implementing a preoperative CardioPulmonary variability assessment; determine if preoperative CardioPulmonary variability is associated with postoperative AEs; and determine if this variability assessment is superior and complementary to existing measures of risk and frailty.",[24,25],"Thoracic Cancer","Complication,Postoperative","RECRUITING","2026-04-27",{"date":29,"type":30},"2026-05-01","ACTUAL",{"date":32,"type":30},"2025-07-01",{"date":34,"type":20},"2026-07-01",{"name":36,"class":37},"Ottawa Hospital Research Institute","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":47,"enrollmentInfo":48,"targetDuration":50,"studyType":21,"phases":4,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":38},"100601510","chinese-ostomy-collaboration-group-cocg-clinical-study--siti-classification-100601510","NCT07111429","Chinese Ostomy Collaboration Group (COCG) Clinical Study -SITI Classification","Evaluation of a Modified Clavien-Dindo Classification (COCG) of Stoma Complication in Cancer Patients: a Prospective, Registry-based, Non-randomized Trial (COCG-01 Trial) on Behalf of Chinese Ostomy Collaboration Group","COCG-SITI","Inclusion Criteria:\n\n* Patients with stoma after colorectal cancer resection.\n\nExclusion Criteria:\n\n* Patients who don't want to be studied","80 Years",{"count":49,"type":20},5000,"3 Years","Colorectal cancer is an important cancer worldwide, and its incidence is increasing year by year. A large proportion of patients may require diverting stoma or even permanent stoma after surgery. Some of these patients will have a variety of stoma-related complications, which seriously affect the quality of life of patients. At present, the mainstream postoperative complication classification is the traditional CD classification, which is suitable for the classification of most postoperative complications. However, due to the unique anatomical characteristics of patients with stoma, the current CD classification system may not be suitable for the classification of patients with stoma-related complications. Therefore, we plan to establish a registry database of colorectal cancer patients with stoma, explore the attribution and incidence of stoma-related complications, and propose a new improved classification system, the SITI classification, on the existing CD classification, for verification and promotion.",[25,53],"Stoma",[55,56],"stoma complications","SITI-CD Classification","NOT_YET_RECRUITING","2025-08-01",{"date":60,"type":30},"2025-08-08",{"date":62,"type":20},"2025-08-15",{"date":64,"type":20},"2025-12-15",{"name":66,"class":37},"Peking University Cancer Hospital & Institute",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":16,"minAge":17,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":101},"100555312","antibiotic-prophylaxis-in-metabolic-bariatric-surgery-100555312","NCT06510452","Antibiotic Prophylaxis in Metabolic Bariatric Surgery","Efficacy of Antibiotic Prophylaxis in Metabolic Bariatric Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n° Patients must be older than 18 and meet the eligibility criteria for MBS as outlined by the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) and the Dutch Federation of Medical Specialists for the surgical treatment of obesity.\n\nExclusion Criteria:\n\n* Patients undergoing immunotherapy or corticosteroid treatment for Crohn's disease or rheumatoid arthritis.\n* Patients with a history of endocarditis require prophylactic antibiotics.\n* Patients with known severe allergies to antibiotics.\n* Patients with active infections or recently treated with antibiotics (within the last 30 days).\n* Patients with compromised immune systems, including those with HIV\u002FAIDS or undergoing chemotherapy.\n* Patients with chronic liver or kidney disease.\n* Patients with uncontrolled diabetes (HbA1c \\> 9%).\n* Patients with a history of previous metabolic bariatric surgery.\n* Pregnant or breastfeeding women.\n* Patients with any other medical condition that, in the opinion of the investigator, would compromise the patient's safety or the study's integrity.",true,"70 Years",{"count":77,"type":20},3352,"INTERVENTIONAL",[80],"NA","SUMMARY Rationale: Prophylactic antibiotics in laparoscopic surgeries, including Metabolic Bariatric Surgery (MBS), are routinely provided to reduce postoperative infections, especially at wound incision sites. However, since incisional wound infections in laparoscopic MBS are rare and morbidity is very low, the benefit of antibiotic prophylaxis is questionable.\n\nObjective: Evaluate the non-inferiority of omitting antibiotic prophylaxis in MBS. Compare postoperative outcomes between Group A (no antibiotics) and Group B (standard antibiotic care) to determine if omission increases complications, particularly wound infections.\n\nStudy Design: Randomized controlled trial (RCT), double-blind.\n\nStudy Population: Patients with obesity eligible for MBS.\n\nIntervention:\n\n* Group A (No Antibiotic Prophylaxis): Undergo MBS without antibiotics to test safety regarding postoperative complications, focusing on surgical site infections (SSIs).\n* Group B (Standard Antibiotic Prophylaxis): Receive standard one-time antibiotics before incision.\n\nMain Study Parameters\u002FEndpoints: Compare the incidence of incisional and organ\u002Fspace SSIs within six weeks post-surgery between Group A and Group B to determine if omitting antibiotics affects infection rates.",[83,84,85,86,25],"Antibiotic Reaction","Wound Infection Superficial","Wound Infection Deep","Bariatric Surgery Candidate",[88,89,90],"anti-biotics","non-inferiority","surgical side infection","2024-07-29",{"date":93,"type":30},"2024-07-31",{"date":95,"type":20},"2024-10-01",{"date":97,"type":20},"2026-04-01",{"name":99,"class":100},"General Committee of Teaching Hospitals and Institutes, Egypt","OTHER_GOV",2,{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":74,"sex":16,"minAge":17,"maxAge":75,"enrollmentInfo":109,"targetDuration":4,"studyType":78,"phases":111,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":38},"100555449","heparin-alone-vs-heparin-aspirin-combo-in-free-flap-survival-100555449","NCT06512233","Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival","Dual Therapy Dilemma: Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival","Inclusion Criteria:\n\n* Patients undergoing free flap surgery\n* Age between 18 and 70 years\n\nExclusion Criteria:\n\n* Known hypersensitivity to heparin or aspirin\n* History of bleeding disorders\n* Concurrent use of other anticoagulant or antiplatelet medications\n* Severe renal or hepatic impairment\n* Preoperative use of aspirin that could not be stopped five days before surgery due to a higher risk of cardiac-related complications.",{"count":110,"type":20},126,[80],"This randomized clinical trial aims to compare the effectiveness of heparin alone versus combination therapy of Heparin- Aspirin in improving free flap survival in patients undergoing reconstructive surgery. Participants will be randomly assigned to receive either heparin or a combination therapy, and the primary outcome measure will be the survival rate of the free flap at various time points post-surgery",[25],[115,116,117,118,119],"Ischemia","Thrombosis","Vascular Complications","Surgical Wound Healing","Reconstructive Surgery Complications","2024-07-19",{"date":122,"type":30},"2024-07-23",{"date":124,"type":20},"2025-01",{"date":126,"type":20},"2025-12",{"name":128,"class":37},"Aga Khan University"]