[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"compression-neuropathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:compression-neuropathy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100635483","vibratory-anesthesia-on-pain-following-corticosteroid-injections-100635483",false,"NCT07553273","Vibratory Anesthesia on Pain Following Corticosteroid Injections","The Effect of Vibratory Anesthesia on Patient Pain Perception in Corticosteroid Injections of the Upper Extremity","Inclusion Criteria:\n\n* Any patient of the Principal Investigator who has clinically diagnosed bilateral arthritis, tendinopathy, arthropathy, or compression neuropathy of the hand, wrist, or elbow where treatment with corticosteroid injection is indicated.\n* Participants who voluntarily consent to participate in the study and sign consent forms.\n* Participants who complete all numeric pain rating scales\n* Patients aged ≥ 18 years old\n\nExclusion Criteria:\n\n* Participants who opt out of the study or withdraw consent\n* Participants who are determined to be without capacity to consent to study participation or injection procedure by principal investigator\n* Participants with inability to complete numeric pain rating scales\n* Participants with known allergies to triamcinolone acetonide, lidocaine, or bupivicaine\n* Participants without clinically diagnosed bilateral arthritis, tendinopathy, arthropathy, or compression neuropathy of the hand, wrist, or elbow.\n* Participants where treatment with corticosteroid injection is not indicated bilaterally.\n* Patients ≤ 18 years old","ALL","18 Years",{"count":19,"type":20},165,"ESTIMATED","INTERVENTIONAL",[23],"NA","This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics. Each individual's perception of pain upon receiving a CSI with two out of three modes of anesthesia (control\u002Fno anesthesia, vibrational anesthesia, vapo-coolant anesthesia) will be utilized to compare these variables and determine the method that is associated with the least pain.",[26,27,28,29,30],"Bilateral Arthritis of Wrist","Tendinopathy","Arthropathy","Compression Neuropathy","Bilateral Arthritis of Hands",[32,33,34],"Pain in Hand","Pain in Elbow","Pain in Wrist","RECRUITING","2026-04-27",{"date":38,"type":39},"2026-05-04","ACTUAL",{"date":41,"type":20},"2026-04",{"date":43,"type":20},"2027-04",{"name":45,"class":46},"The University of Texas Medical Branch, Galveston","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":59,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100538744","phase-2-4ap-for-carpal-tunnel-syndrome-cts-100538744","NCT06294821","4AP for Carpal Tunnel Syndrome (CTS)","4-Aminopyridine to Delay Carpal Tunnel Release or Resolve Carpal Tunnel Syndrome","CTS","Inclusion Criteria:\n\n* Patients diagnosed with non-traumatic carpal tunnel syndrome without any other confounding diagnosis (e.g. cubital tunnel syndrome, cervical nerve compression)\n* Standard of care EDX testing within 6 months of study enrollment\n* Cognitive ability to report sensory and motor deficit during examination.\n* Able to complete twice daily dosing of 4-AP for the entire 6 week treatment period.\n* Adults subject aged 18-90\n* Ability to give written informed consent.\n* Capable of safely undergoing electrodiagnostic testing (EDX).\n* Availability for all study visits.\n\nExclusion Criteria:\n\n* Inability to complete twice daily dosing during 6 week treatment period.\n* History of multiple sclerosis, stroke or any other diagnosed neurological disorder\n* History of hypersensitivity to AMPYRA® or 4-aminopyridine\n* Current use of aminopyridine medications, including other compounded 4-AP\n* Suspected renal impairment based on the Choyke questionnaire.","90 Years",{"count":58,"type":20},160,[60],"PHASE2","The investigators have found recent promising data supporting the use of a currently FDA approved drug, 4-aminopyridine, in the treatment of nerve injury including compression neuropathy. The purpose of this research is determine whether 4-aminopyridine can treat carpal tunnel syndrome or delay the need for formal surgical release in patients with known carpal tunnel syndrome who would otherwise undergo surgery.",[29,63],"Carpal Tunnel Syndrome",[65,66,67,68,54,69,70],"4 aminopyridine","carpal tunnel syndrome","CTR","4AP","Carpal tunnel release","compression neuropathy","NOT_YET_RECRUITING","2026-01-22",{"date":74,"type":39},"2026-01-26",{"date":76,"type":20},"2026-11",{"date":78,"type":20},"2028-07",{"name":80,"class":46},"John Elfar"]