[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"congenital-anomalies\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:congenital-anomalies":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100605784","result-of-karyotyping-in-pediatric-patients-with-congenital-anomalies-and-developmental-delay-100605784",false,"NCT07167017","Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay","Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay at Assiut University Children Hospital","Inclusion Criteria:\n\nAll patients aged between 1 month to 12 years old who are presented with morphologic congenital anomalies associated with developmental delay either global DD or isolated developmental domain (cognitive, motor, speech and language or social) who are tested for chromosomal abnormalities\n\nExclusion Criteria:\n\nAny patient aged between 1 month and 12 years old who is presented with Developmental Delay and congenital anomalies who didn't undergo karyotyping or other genetic testing.","ALL","1 Month","12 Years",{"count":20,"type":21},75,"ESTIMATED","OBSERVATIONAL","The goal of this observational cross-sectional study is to study the results of karyotyping analysis for children presented with congenital anomalies and developmental delay aged 1 month to 12 years, the need for further genetic tastings and identification of parents who are carrier of balanced chromosomal translocations. The main question it aims to answer:\n\nWhat the is the incidence of congenital anomalies tested by karyotyping and the type of chromosomal abnormalities causing the clinical features.\n\nResearcher will take detailed clinical history, physical examination and developmental assessment for children and interpret karyotyping results.\n\nFor participants data will be collected regarding:\n\n1. History will be taken including demographic data of child age, parental age, consanguinity and relevant family history and developmental history.\n2. Clinical examination for any fascial dysmorphism, congenital heart disease, skeletal deformities, renal anomalies or any associated features.\n3. Clinical assessment of developmental milestones.\n4. Investigations done including laboratory tests, ultrasound scan, x-rays, CT scan, echocardiography or any other investigation.\n5. Karyotyping results detected if aneuploidy or structural abnormality including chromosomal deletions, duplications, translocations or inversions.\n6. Other genetics tests done including Comparative microarray, FISH (Fluorescence in Situ Hybridization), and WES (Whole Exome Sequencing).\n7. If parental karyotyping for suspected translocations was done.",[25,26],"Congenital Anomalies","Development Delay",[28,29,30],"karyotyping","congenital anomalies","developmental delay","NOT_YET_RECRUITING","2025-09-03",{"date":34,"type":35},"2025-09-11","ACTUAL",{"date":37,"type":21},"2025-11-01",{"date":39,"type":21},"2026-12",{"name":41,"class":42},"Assiut University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":16,"minAge":50,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100597889","ai-powered-neonatal-risk-assessment-for-improved-perinatal-outcomes-100597889","NCT07064356","AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes","Inclusion Criteria:\n\n* Historical, de-identified neonatal records including ultrasound images, MRI scans, and clinical documentation available for analysis.\n\nExclusion Criteria:\n\n* Cases with incomplete or missing critical data elements required for AI model analysis.",true,"1 Year",{"count":52,"type":21},50000,"This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans. The objective is to empower clinicians and provide clear, compassionate support for families navigating complex prenatal diagnoses.",[25,55,56,57],"Neonatal Complications","Perinatal Outcomes","Perinatal Outcomes of the Mother and Fetus",[59,60,61,62,63],"Artificial Intelligence","Predictive Diagnostics","Machine Learning","Fetal Medicine","Neonatal Risk Assessment","2025-07-03",{"date":66,"type":35},"2025-07-14",{"date":68,"type":21},"2025-07",{"date":70,"type":21},"2026-06",{"name":72,"class":73},"FetalFirst Limited","INDUSTRY",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":82,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100579176","quality-of-information-provided-during-antenatal-consultations-100579176","NCT06820892","Quality of Information Provided During Antenatal Consultations","Evaluation of the Concordance Between the Information Delivered in Antenatal Diagnosis Consultation and Parents Experience After the Birth of Their Infant","EVIDANCE","Inclusion Criteria:\n\n* Patients were observed at the multidisciplinary prenatal diagnosis centre.\n* Patients who had attended at least one antenatal consultation with a pediatric neonatologist\n* Patients who gave birth between January 2020 and December 2022 and whose newborn was hospitalized in the neonatology department\n\nExclusion Criteria:\n\n* a child who died in hospital or had a condition with a high risk of death in the first few years of life\n* non-French speaking mothers\n* Mothers who were minors at the time of the study","FEMALE","18 Years",{"count":85,"type":21},113,"The objective of this questionnaire study is to evaluate the concordance between the information provided to parents during antenatal consultations and their subsequent experiences following childbirth.",[25,88,89],"Prematurity","Antenatal Consultation",[91,92,93],"Antenatal","Antenatal consultation","information","RECRUITING","2025-02-10",{"date":97,"type":35},"2025-02-11",{"date":99,"type":35},"2024-08-02",{"date":101,"type":21},"2025-03-15",{"name":103,"class":42},"Hospices Civils de Lyon",1]