[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"congenital-melanocytic-nevi\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:congenital-melanocytic-nevi":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100562611","understanding-the-transition-from-normal-melanocytes-to-nevus-to-melanoma-100562611",false,"NCT06605417","Understanding the Transition from Normal Melanocytes to Nevus to Melanoma","Understanding the Transition from Normal Melanocytes to Nevus to Melanoma (NevustoMel)","NevustoMel","Inclusion criteria:\n\n* Congenital nevus with estimated size of 20 cm\n* Be over 18 years of age\n\nExclusion criteria:\n\n* No available biological material\n* Not having signed the informed consent","ALL",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L\u002FGCMN. The secondary objectives are:\n\n* To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients.\n* To improve the early diagnosis and treatments for intermediate conditions such as L\u002FGCMN through evidence-based interpretation of personal risk from endogenous or exogenous sources.\n* To test pre-clinical strategies to best model and improve patient response.",[24,25,26],"Congenital Melanocytic Nevi","Melanoma, Skin","Nevi and Melanomas",[28,29,30,31,32,33,34,35],"Congenital melanocytic nevi","Melanoma","Liquid biopsy","cfDNA","Methylomics","L\u002FGCMN","RNAseq","Molecular profiles","RECRUITING","2025-02-25",{"date":39,"type":40},"2025-02-27","ACTUAL",{"date":42,"type":40},"2024-01-01",{"date":44,"type":20},"2026-11-30",{"name":46,"class":47},"Fundacion Clinic per a la Recerca Biomédica","OTHER",2]