[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"consciousness-loss-of\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:consciousness-loss-of":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100546894","analysis-of-deep-brain-nuclei-lfp-and-cortical-eeg-signals-during-the-recovery-from-general-anesthesia-100546894",false,"NCT06400901","Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia","Electrophysiology Based Brain Network Study on Deep Brain Nuclei LFP and Cortical EEG During the Recovery From General Anesthesia","Inclusion Criteria:\n\n* 18-75 years old\n* ASA (American Society of Anesthesiologists) classification I-III\n* Those who meet the indications for DBS surgery\n* Right-handed with normal listening and speaking abilities\n* The patient signs the informed consent form and cooperates with the researchers\n\nExclusion Criteria:\n\n* Patients with cognitive impairment \\[Montreal Cognitive Assessment (MoCA) score less than 26 points\\];\n* Patients with severe depression \\[Beck Depression Inventory (BDI-II) score greater than or equal to 25 points\\];\n* Patients with important organs dysfunction, such as heart, lungs, liver, and kidneys; or patients with unstable vital signs;\n* Patients who are expected to enter the ICU after surgery;\n* Patients who are alcoholic, alcohol dependent or drug dependent;\n* Patients who have received general anesthesia one month before surgery, patients who are known to be allergic to general anesthetics;\n* The DBS surgery exceeds 4 hours;\n* Patients who are pregnant.","ALL","18 Years","75 Years",{"count":20,"type":21},42,"ESTIMATED","OBSERVATIONAL","The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp electroencephalogram (EEG) of the frontal cortex were recorded from patients undergoing deep brain stimulation (DBS) surgery during the recovery from general anesthesia, in order to explore the changes and relevance of deep brain nuclei firing and cortex activity during the recovery of consciousness from general anesthesia .",[25,26,27,28],"Deep Brain Stimulation Surgery","Electrophysiology","General Anesthesia","Consciousness, Loss of",[30,31,32,33],"cortex EEG","deep brain nuclei","local field potentiation","propofol","RECRUITING","2024-05-09",{"date":37,"type":38},"2024-05-13","ACTUAL",{"date":40,"type":21},"2024-05-15",{"date":42,"type":21},"2026-10-15",{"name":44,"class":45},"Ruijin Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":56,"conditions":57,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":46},"100543949","incidence-of-episodes-of-disconnected-consciousness-among-emergency-patients-admitted-in-the-resuscitation-room-100543949","NCT06362525","Incidence of Episodes of (Dis)Connected Consciousness Among Emergency Patients Admitted in the Resuscitation Room","Inclusion Criteria:\n\n* patients admitted in the resuscitation room of our university hospital\n* French speaking\n\nExclusion Criteria:\n\n* Refusal\n* Chronic disorder of consciousness\n* Deafness\n* Blindness\n* Dementia\n* Hemineglect\n* Aphasia",true,{"count":55,"type":21},100,"This observational study aims to describe the incidence of episodes of disconnected consciousness (including near-death experience (NDE)) and episodes of connected consciousness in patients admitted to the resuscitation room, who survived a critical condition and who meet at least one of these criteria during their stay in the resuscitation room: (1) deep sedation, (2) intubation, (3) cardiopulmonary resuscitation, or (4) (non-drug-induced) Glasgow Coma Scale score = 3. We also investigate the potential (neuro)physiological markers and biomarkers. In order to help determine the potential risk factors of such episodes, cognitive factors such as dissociative propensity are also investigated. Unexpected visual and auditory stimuli will be displayed. In addition, we assess the evolution of memory, as well as short- and long-term consequences on quality of life, anxiety, and attitudes towards care.\n\nMemory of patients who did not meet the above-mentioned criteria are also investigated. A group of 15 healthy participants will be invited to test the stimuli display.\n\nFinally, (neuro)physiological parameters of a subsample of dying patients are also investigated.",[58,59,28,60,61],"Critical Illness","Near-Death Experience","Quality of Life","Emergencies",[63],"Dream","2024-04-08",{"date":66,"type":38},"2024-04-12",{"date":68,"type":38},"2023-10-09",{"date":70,"type":21},"2027-09-30",{"name":72,"class":45},"University of Liege"]