[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"contingency-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:contingency-management":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,71,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100600948","substance-use-in-pregnant-people---optimizing-retention-in-treatment-100600948",false,"NCT07104123","Substance Use in Pregnant People - Optimizing Retention in Treatment","Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management","SUPPORT-MOM","Inclusion Criteria:\n\nConfirmed viable intrauterine pregnancy at any gestational age, or within three years postpartum\n\nSUD as defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders or clinician documentation\n\nExclusion Criteria:\n\nDecline follow-up care at study site\n\nRequire immediate hospitalization for unstable medical or psychiatric conditions making them clinically unsuitable to participate in a research study","FEMALE","18 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instability, transportation barriers, and limited childcare access, further exacerbate disparities in treatment retention.\n\nThis pilot study, conducted in two specialized prenatal care clinics, evaluates the feasibility and acceptability of two integrated strategies to promote sustained engagement in recovery-oriented services during the perinatal and postpartum periods. Aim 1 implements a standardized social needs screening and referral protocol to connect patients with community-based supports. Aim 2 pilots a contingency management intervention to incentivize recovery-supportive behaviors.\n\nFindings will inform the design of a larger multi-site randomized controlled trial to evaluate the impact of these interventions on treatment retention, overdose prevention, and maternal-infant health outcomes.",[27,28,29,30],"Substance Use Disorder (SUD)","Pregnancy","Postpartum","Contingency Management","RECRUITING","2026-06-17",{"date":34,"type":35},"2026-06-22","ACTUAL",{"date":37,"type":35},"2026-02-02",{"date":39,"type":21},"2027-09",{"name":41,"class":42},"Washington University School of Medicine","OTHER",2,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100630235","maternal-outcomes-mood-alcohol-use-and-depressive-symptoms-100630235","NCT07485036","Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms","Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms (MOMS-AD Pilot Study)","MOMS-AD","Inclusion Criteria:\n\n* Biologically female\n* Age ≥18 years\n* Within 12 months postpartum\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Serious medical or psychiatric conditions requiring hospitalization\n* Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychiatric disorder\n* Current use of psychoactive drugs, medication to treat problematic alcohol use, or depression\n* Participation in past 6 months in problematic alcohol use or substance use treatment\n* Unable to provide consent",{"count":53,"type":21},30,[24],"This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms. The main questions it seeks to answer are:\n\n1. How do new mothers fare with depressive symptoms and alcohol use in the first 12 months after giving birth?\n2. Will a CM-PST intervention reduce depressive symptoms and alcohol use frequency among new mothers?\n3. Is a CM-PST intervention practical for new mothers?\n\nThe researchers will recruit approximately 30 new mothers and randomly select half to attend a 6-week CM-PST intervention. They will compare those who received the intervention versus those who did not to see if there are any differences in their depressive symptoms and alcohol usage.\n\nParticipants will:\n\n* Complete 4 remote intervention sessions over 6 weeks\n* Conduct at-home urine drug tests 2x per week during the 6-week intervention\n* Answer online surveys about their mental health and alcohol use",[57,58,30,59],"Postpartum Depression (PPD)","Alcohol Use","Problem Solving Therapy","NOT_YET_RECRUITING","2026-05-05",{"date":63,"type":35},"2026-05-11",{"date":65,"type":21},"2026-06-01",{"date":67,"type":21},"2027-11-30",{"name":69,"class":42},"University of Illinois at Chicago",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":18,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":70},"100552784","j-rise-relevant-implementation-strategies-to-eliminate-the-social-and-structural-barriers-to-hiv-services-among-justice-involved-black-men-who-have-sex-with-men-and-other-key-populations-100552784","NCT06477588","J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations","J-RISE","Inclusion Criteria:\n\n1. be at least 18 years of age;\n2. currently reside or intend to reside in one of the study communities (i.e., Cook County, Baton Rouge, and the New Orleans area);\n3. be able to provide informed consent in English and complete the study in English. In addition, potential participants must:\n4. be currently incarcerated in jail or prison and report an expected release within 90 days, or under community supervision or drug court, or report a recent incarceration within the last three years, or in the last 12 months has had an interaction with law enforcement that did not lead to an arrest or jail or prison time, AND has not already been linked and\u002For retained in HIV or PrEP care in the community;\n5. report needing employment-related services; and\n6. have a confirmed HIV positive or negative status (within 90 days of enrollment) and if HIV negative meets one of CDC's PrEP indications (i.e., sexually active, needle sharing, previous STI history in the last 24 months) or plans to have sex in the next 12 months or wants more information about PrEP.\n\nExclusion Criteria:\n\n1. unwilling\u002Funable to provide informed consent,\n2. does not live or intend to live in one of the study locations,\n3. unable to confirm HIV status,\n4. unable to conduct the study in English, and\n5. currently enrolled in another intervention to support HIV care, PrEP care, and economic stability.",true,"ALL",{"count":81,"type":21},350,[24],"The goal of this clinical trial is to compare two interventions - Health Navigation and Health Navigation Plus among individuals who have been impacted by the criminal legal system.\n\nThe main question it aims to answer is:\n\n• Compared with the Health Navigation group, are participants in the Health Navigation Plus group more likely to a) access HIV care, treatment, and prevention services and employment services and b) access employment services and be employed in community?\n\nParticipants on the study will be:\n\n* Randomly assigned (like a flip of a coin) to participate in either Health Navigation or Health Navigation Plus. Participants will have an equal chance of being placed in either group.\n* Complete three surveys over the course of 13 months\n* Participants in the Health Navigation group will have two in person meetings and seven check-ins with the health navigator over 6 months\n* Participants in the Health Navigation Plus group will have two in person meetings and seven check-ins with the health navigator over 6 months, two in person and 10 check ins with the employment navigator over 12 months and up to $200 to support employment and career development needs and receive up to $140 to support health goals. Samples of blood, urine and swabs may be collected to meet the health goals.",[85,30,86,87,88,89],"HIV","Justice Involved Populations","Status Neutral Interventions","Mental Health","Substance Use",[85,91,92,93,94,95,96,97],"Contingency management","Justice involved populations","Status neutral interventions","mental health","substance use","employment","PrEP","2026-04-17",{"date":100,"type":35},"2026-04-21",{"date":102,"type":35},"2024-08-13",{"date":104,"type":21},"2028-06-30",{"name":106,"class":42},"University of Chicago",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":79,"minAge":18,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":119,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":70},"100587654","why-wait-initiating-contingency-management-in-traumatically-injured-patients-during-hospitalization-100587654","NCT06931197","Why Wait? Initiating Contingency Management in Traumatically Injured Patients During Hospitalization","Inclusion Criteria:\n\n* Admitted trauma patients\n* Age greater than 18 years old\n* Urine drug screen positive for methamphetamines during the current hospitalization\n* Report at least weekly methamphetamine use\n* First methamphetamine use greater than 6 months prior to injury\n* Report at least 4 Diagnostic and Statistical Manual of Mental Disorders 5th Edition, Amphetamine-Type Substance Use Disorder symptoms (at least moderate disease)\n* Glasgow Coma Scale ≥13 upon arrival to the emergency department\n* Ability to understand and participate in study procedures\n* Ability to communicate in English\n* Expected discharge date within 45 days on the day of screening \u002F recruitment\n\nExclusion Criteria:\n\n* Active psychosis (reporting auditory or visual hallucinations)\n* Under ongoing cardiorespiratory monitoring\n* Evidence of moderate or severe traumatic brain injury\n* Patients who are known to be pregnant\n* Prisoners\n* Individuals incarcerated at the time of their hospitalization\n* Individuals lacking capacity to provide, or are otherwise unable or unwilling to provide written informed consent",{"count":114,"type":21},20,[24],"This clinical trial is to implement contingency management (CM) as an intervention tool to address methamphetamine use and will be initiated during inpatient acute hospitalization in trauma injured patients.\n\nThe goals are:\n\n* Gather effectiveness data on a CM program for participants in Hawaii who use methamphetamine during hospitalization and following discharge due to trauma injury\n* To assess participant perspectives on engaging with a CM program based at a Level 1 Trauma Center. Researches will assess both patient-reported and biologically-confirmed medium-term program effectiveness and conduct qualitative interviews with participants post-program.\n* To assess the rate of leaving against medical advice (AMA) and treatment completion in acute hospital setting in participants.\n* To assess the optimal timing of CM initiation for traumatically injured hospitalized patients by comparing patient outcomes (i.e. duration of CM participation and rates of CM program completion and providing negative urine samples) to NCT06532370 where CM was initiated after discharge from the hospital.\n\nFor total of 12 weeks, participants will:\n\n* Be visited on Mondays\u002FThursdays or Tuesdays\u002FFridays by the research team to complete urine analysis during the hospitalization\n* Visit a follow up clinic up to 2 times per week on Mondays\u002FThursdays or Tuesdays\u002FFridays to complete urinalysis following discharge from the hospital\n* Complete Treatment Effectiveness Assessments at 6 and 12 weeks\n* Engage in qualitative interview at the end of the CM program",[30,118],"Methamphetamine Use Disorder",[91,118,120,121],"Contingency management during acute hospitalization","Contingency management in Trauma Injured Patients","2025-12-09",{"date":124,"type":35},"2025-12-17",{"date":126,"type":21},"2026-01-01",{"date":128,"type":21},"2026-07-31",{"name":130,"class":42},"Queen's Medical Center"]