[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"continuous-glucose-monitoring-system\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:continuous-glucose-monitoring-system":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100634798","mediterranean-diet-and-oxidative-stress-in-type-1-diabetes-medox-t1d-100634798",false,"NCT07544368","Mediterranean Diet and Oxidative Stress in Type 1 Diabetes (MEDOX-T1D)","The Relationship Between Adherence to the Mediterranean Diet and Oxidative Stress in Children With Type 1 Diabetes","MEDOX-T1D","Inclusion Criteria:\n\n* Ages 10-18 years\n* BMI between the 5th and 95th percentile (normal to overweight)\n* Diagnosis of Type 1 Diabetes for ≥1.5 years\n* Users of a continuous glucose monitoring (CGM) system\n* No other comorbidities and not taking medications\n* Non-smokers and non-alcohol users (including e-cigarettes)\n* Written informed consent provided by the participant and their parent\u002Fguardian\n\nExclusion Criteria:\n\n* Presence of any acute or chronic disease other than Type 1 Diabetes\n* Current use of any medications\n* BMI ≥ 95th percentile (obese)\n* Presence of an eating disorder\n* Use of tobacco, e-cigarettes, or alcohol","FEMALE","10 Years","18 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","Achieving optimal glycemic control in type 1 diabetes requires a holistic approach that includes individualized medical nutrition therapy in addition to appropriate insulin therapy. When diabetes is poorly managed, metabolic control is impaired. Hyperglycemic events increase oxidative stress in the body and can lead to complications. The aim of this study is to examine the effect of a 12-week Mediterranean diet on oxidative stress markers in children with type 1 diabetes who do not meet the metabolic target (HbA1c \\> 7%) and whose adherence to the Mediterranean diet is \"poor\" and \"needs improvement\".\n\nThe study, planned between March 2026 and March 2027, will be conducted with girls aged 10-18 years with type 1 diabetes who are followed up at the Department of Pediatric Endocrinology, Istanbul Faculty of Medicine, Istanbul University. In the first phase, participants were divided into groups based on their HbA1c levels: those with HbA1c ≤ 7 met the metabolic target (Group A); Those with HbA1c \\> 7 will be divided into two groups: those not meeting the metabolic target (Group B). In the second stage, the intervention group will be determined according to the results of the KIDMED, the pediatric Mediterranean diet adherence scale. Those in Group B who did not meet the metabolic targets and those with \"poor\" and \"need improvement\" KIDMED results will form the intervention group (Group C). Adolescents in Group C will receive a 12-week Mediterranean diet intervention. Information will be collected from participants using questionnaires, scales, and experimental methods. This includes completing the 'Personal Information Form', 'Biochemical Parameters Form', '3-Day Nutrition Questionnaire', 'KIDMED scale', and 'Sensor Data Form'. The obtained data will be analyzed both individually and before-and-after using SPSS 26.\n\nThe findings are expected to show improvement in OS markers in the intervention group. Improvement in glycemic control markers is also predicted. A decrease in HbA1c levels, a reduction in blood sugar fluctuations, and an increase in the duration of staying within the target range are expected.\n\nThis study is expected to contribute to the literature by revealing the effects of the Mediterranean diet on oxidative stress and metabolic control parameters in type 1 diabetes. It is anticipated that the findings will support the potential role of dietary approaches with antioxidant properties not only in glycemic control but also in oxidative stress levels and long-term complication risks.",[28,29,30],"Type 1 Diabetes (Juvenile Onset)","Continuous Glucose Monitoring System","Oxidative Stress",[32,33,30],"Type 1 Diabetes","Mediterranean Diet","NOT_YET_RECRUITING","2026-04-24",{"date":37,"type":38},"2026-04-29","ACTUAL",{"date":40,"type":22},"2026-04",{"date":42,"type":22},"2027-03",{"name":44,"class":45},"Istanbul University","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100585218","creating-linked-inpatient-cgm-for-kids-100585218","NCT06899503","Creating Linked Inpatient CGM for Kids","CLICK: Creating Linked Inpatient CGM for Kids","CLICK","Inclusion Criteria:\n\n* Inpatients with diabetes using a Dexcom G7 CGM\n* Technology\u002Fdata sharing criteria: use of the Dexcom G7 phone app and data sharing with the BCH Dexcom Clarity Database\n* Anticipated discharge date \\>24 hours after study eligibility\n\nExclusion Criteria:\n\n* Use of medications that interfere with CGM accuracy\n* Use of a Dexcom receiver to view data (rather than the typical mobile phone)\n* Enrollment in a competing clinical trial","ALL","2 Weeks","24 Years",{"count":58,"type":22},20,"OBSERVATIONAL","Continuous glucose monitors (CGMs) are currently used in the inpatient setting at many hospitals for the care of patients with diabetes and for clinical research studies. This includes Boston Children's Hospital, however, the CGM data is not accessible to clinical or research teams in real-time. CGMs measure and display a patient's glucose level every 5 minutes and provide alerts for predicted or actual low or high glucose levels. The CGM data is currently only accessible on bedside handheld receivers or a mobile device app, neither of which sync with the hospital EMR or other hospital databases. This observational study tests a companion mobile Android device app that wirelessly receives real-time outputs from the Dexcom G7 CGM app and transmits the data to a centralized hospital database. That database in turn feeds into an internal BCH web dashboard which allows live data viewing and integration into future clinical decision support tools.\n\nThe investigators are testing the hypothesis that the companion mobile app can accurately and efficiently transmit CGM data to a hospital database. Data will be analyzed for accuracy and efficiency by comparing CGM readings captured by the companion app to CGM readings documented in the formal Dexcom database. Accuracy (difference between CGM readings from both sources) and efficiency (number of CGM readings captured) will be assessed. The findings will be generalizable to using the companion app in future research studies.",[62,29],"Diabetes",[62,64,65],"Continuous glucose monitoring system","Android application","2026-04-01",{"date":68,"type":38},"2026-04-03",{"date":70,"type":22},"2027-01",{"date":72,"type":22},"2028-01",{"name":74,"class":45},"Boston Children's Hospital",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":110},"100607147","cgm-adherence-compared-to-finger-stick-glucose-monitoring-in-pregnancies-with-type-2-pregestational-diabetes-100607147","NCT07184775","CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes","Maternal Continuous Glucose Monitoring Surveillance Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes","PRECIOUS","Inclusion Criteria:\n\n* singleton pregnancies\n* fetuses without anomalies\n* diagnosis of Type 2 diabetes\n* initiation of prenatal care at \\\u003C20 weeks gestation\n\nExclusion Criteria:\n\n* diagnosis of Type 1 diabetes\n* allergy to insulin\n* inability to wear a continuous glucose monitor",{"count":85,"type":22},70,[25],"The purpose of this study is to compare patient adherence to blood sugar monitoring during pregnancy using two different measurement methods in pregnancies complicated by pregestational type 2 diabetes (T2DM). Pregnant patients with T2DM are at risk of having larger babies, babies with low sugar levels in the first 24 hours of life, higher rates of cesarean delivery, stillbirth (death of baby inside the womb), and hypertensive or high blood pressure disorders of pregnancy, such as preeclampsia. Prior studies have shown that treating high blood sugars in pregnancy with medications can reduce these risks. To determine the amount of medication needed, recording of blood sugar levels is necessary. This trial aims to determine whether continuous blood sugar monitors have improved patient recording of blood sugar levels over finger stick blood sugar measurements.\n\nPatients involved in the study will be assigned to either:\n\n1. Fingerstick glucose monitoring (FSG)\n2. Continuous glucose monitoring (CGM)\n\nPatients will be randomize in a 1:1 ratio.\n\nFSG Group: blood sugar is tested four times daily - once fasting and two hours after every meal (post-prandial). Blood will be tested using a glucometer, and values will be recorded in a blood sugar log from the time of enrollment to the time of delivery.\n\nCGM Group: A CGM sensor will be placed on the patient's arm for blood sugar collection every 3-5 minutes. This data is sent to a phone application from the time of enrollment to the time of delivery. These sensors will need to be replaced every 14 days.\n\nPercent adherence will be recorded from the time you were randomized to a study group until delivery.",[89,90,29],"Type 2 Diabetes Mellitus (T2DM)","Pregnancy",[92,62,93,94,95,96,97,98,99],"Type 2 Diabetes","continuous glucose monitor","CGM","adherence","pregnancy","maternal health","prenatal care","glucose monitoring","RECRUITING","2025-10-12",{"date":103,"type":38},"2025-10-14",{"date":105,"type":38},"2025-10-01",{"date":107,"type":22},"2026-03-01",{"name":109,"class":45},"Thomas Jefferson University",2]