[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"controlled-hypotension-for-nasal-surgeries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:controlled-hypotension-for-nasal-surgeries":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100642447","remifentanil-vs-nicardipine-for-controlled-hypotension-in-elective-nasal-surgery-100642447",false,"NCT07660562","Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery","Comparison of Remifentanil and Nicardipine Infusions for Controlled Hypotension in Elective Nasal Surgery Where Bleeding Control is Critical: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age \\> 18 years\n* ASA physical status I-II\n* Scheduled for elective nasal surgery\n* No known serious cardiovascular, respiratory, renal, or hepatic disease\n* No known allergy to remifentanil or nicardipine\n* No chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents\n* Not pregnant or breastfeeding\n* BMI ≤ 35 kg\u002Fm²\n* No emergency surgical indication\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* ASA III or above\n* Known serious cardiovascular, respiratory, renal, or hepatic disease\n* Known allergy to remifentanil or nicardipine\n* Chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents\n* Pregnancy or breastfeeding\n* Morbid obesity (BMI \\> 35 kg\u002Fm²)\n* Emergency surgery\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},44,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods. The study evaluates hemodynamic stability, surgical field quality (Fromme-Boezaart score), tissue perfusion, intraoperative blood loss, surgeon satisfaction, and perioperative adverse effects.",[26,27,28],"Nasal Surgery","Anesthesia","Controlled Hypotension for Nasal Surgeries","NOT_YET_RECRUITING","2026-06-16",{"date":32,"type":33},"2026-06-22","ACTUAL",{"date":35,"type":20},"2026-06-25",{"date":37,"type":20},"2026-07-15",{"name":39,"class":40},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":70},"100628316","comparison-of-two-sedative-agents-in-terms-of-controlled-hypotension-100628316","NCT07460050","Comparison of Two Sedative Agents in Terms of Controlled Hypotension","COMPARISON OF PROPOFOL INFUSION VS INHALATIONAL AGENT ISOFLURANE IN TERMS OF CONTROLLED HYPOTENSION IN PATIENTS UNDERGOING ENDOSCOPIC SINUS SURGERY","Inclusion Criteria:\n\n* Either male\u002Ffemale Age 18-65 Patients undergoing endoscopic sinus surgery as per the operational definition\n\nExclusion Criteria:\n\n* Patients with cardiovascular disease Patients with pregnancy Patients with coagulopathy Patients on beta blockers or calcium channel blockers",true,"65 Years",{"count":51,"type":20},136,[23],"Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention. So, it provides a better visiblity of surgical filed to the surgeons.This RCT compares propofol infusion vs isoflurane inhalation for inducing controlled hypotension during endoscopic sinus surgery. The goal is to assess which agent better controls blood pressure, improves surgical field visibility, and impacts recovery. It likely measures outcomes like hemodynamics, bleeding, and surgeon satisfaction.",[28],[56,57,58,59],"Controlled hypotention","Propofol infusion","Endoscopic sinus surgery","Isoflurane inhalation","2026-03-04",{"date":62,"type":33},"2026-03-10",{"date":64,"type":20},"2026-03-01",{"date":66,"type":20},"2026-08-01",{"name":68,"class":69},"Hayatabad Medical Complex","OTHER_GOV",1]