[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"copd-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:copd-patients":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":35,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100620748","the-revive-pivotal-study-100620748",false,"NCT07361653","The REVIVE Pivotal Study","A Prospective, Global, Multicenter, Randomized, Double Blind, Sham Controlled Study to EValuate the Safety and effectIVEness of the Ryme Medical Targeted Lung Denervation (TLD) Catheter in Patients With Moderate and Severe Symptomatic Chronic Obstructive Pulmonary Disease (COPD) - The REVIVE Pivotal Study","REVIVE","Inclusion Criteria:\n\n* Symptomatic chronic obstructive pulmonary disease\n* History of COPD exacerbation(s)\n* Stable medical therapy\n* Candidate for bronchoscopy\n\nExclusion Criteria:\n\n* Prior lung intervention with device in place\n* Using tobacco products, e-cigarettes, vape or other inhaled non-pharmacological substance\n* Clinically significant serious or unstable medical conditions (e.g., heart disease requiring treatment, uncontrolled diabetes)\n* Pregnant, nursing, or intent to become pregnant during study duration","ALL","40 Years","80 Years",{"count":21,"type":22},300,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this study is to test whether a new treatment called the Ryme Medical Targeted Lung Denervation (TLD) Catheter is safe and effective for people with moderate to severe chronic obstructive pulmonary disease (COPD).\n\nThe main questions it aims to answer are:\n\n1. Does the TLD Catheter improve symptoms in people with COPD?\n2. Is the TLD Catheter safe ?\n\nResearchers will compare the group receiving the TLD treatment to the group receiving a sham procedure to see if the treatment improves quality of life.\n\nParticipants will:\n\n1. Be randomly assigned to receive either the TLD treatment or a sham procedure.\n2. Undergo the assigned procedure in a hospital setting.\n3. Attend follow-up visits for health checks and breathing tests.",[28,29,30,31,32,33,34],"COPD (Chronic Obstructive Pulmonary Disease)","COPD Exacerbations","COPD Patients","COPD Acute Exacerbation","COPD","Lung Disease Airways","Lung Disease, Chronic Obstructive",[32,36,37],"Targeted Lung Denervation","Chronic Obstructive Pulmonary Disease","NOT_YET_RECRUITING","2026-04-29",{"date":41,"type":42},"2026-05-05","ACTUAL",{"date":44,"type":22},"2026-06",{"date":46,"type":22},"2029-12",{"name":48,"class":49},"Ryme Medical, Inc.","INDUSTRY",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":76},"100552931","effects-of-pilate-versus-aerobic-exercises-on-dyspnea--functional-capacity-and-anxiety-status-in-patients-with-copd-100552931","NCT06479499","Effects of Pilate Versus Aerobic Exercises on Dyspnea , Functional Capacity and Anxiety Status in Patients With COPD","Inclusion Criteria:\n\n* The both male and female participants will be included in the study.\n* The age of included participants will be 45-65 years old.\n* Diagnosed COPD patients of stage 2-3 according to gold criteria (moderate)\n* When the patients started the exercise program, they were stable, and none of them showed any clinical signs of neuromuscular or cardiovascular conditions that would prevent them from exercising.\n* The selected participants are getting medical therapy with pulmonary medications.\n* Those participants who will sign a written informed consent form will be included in the study.\n\nExclusion Criteria:\n\n* Participants who had recent abdominal and chest surgeries will be excluded.\n* Patients having history of cardiac arrhythmias or potential ECG alterations,\n* Patients who are unable to follow commands.\n* Participants presented with severe neuro-musculoskeletal abnormalities.\n* The chosen individuals were smokers or former smokers with a medical history of COPD; none of them exhibited any physiological or clinical signs of bronchial asthma.\n* No involvement in a consistent workout regimen for a minimum of six months before the study's start.\n* Those participants who are doing Yoga.","45 Years","65 Years",{"count":59,"type":22},32,[25],"This study aims to compare the effects of Pilates, with its emphasis on proper breathing and muscle activation, and aerobic exercises, known for improving cardiovascular fitness, on dyspnea, anxiety, and functional capacity in COPD patients.",[30],[64],"Aerobic exercises","RECRUITING","2024-06-24",{"date":68,"type":42},"2024-06-28",{"date":70,"type":42},"2023-11-23",{"date":72,"type":22},"2024-06-18",{"name":74,"class":75},"Riphah International University","OTHER",1]