[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"corneal-melting-in-boston-keratoprosthesis-type-i\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:corneal-melting-in-boston-keratoprosthesis-type-i":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100288987","corneal-collagen-crosslinking-to-increase-the-resistance-of-the-support-graft-of-the-kpro-type-i-against-corneal-melting-100288987",false,"NCT03041883","Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting","Corneal Collagen Crosslinking to Increase the Resistance of the Graft Used as a Support for the Boston Keratoprosthesis Type I Against Corneal Melting","CXL-KPro","Inclusion Criteria:\n\n* Candidate for KPro type I\n* Capacity to give written consent\n* Ability to be followed for the duration of the study\n\nExclusion Criteria:\n\n* Participation in another interventional study\n* Failure to wear a therapeutic contact lens due to abnormalities of the eyelids.\n* Inability to give written consent\n\nContraindications to the KPro type I:\n\n* Severe dryness with keratinization of the ocular surface\n* Intraocular tumor\n* Terminal glaucoma\n* Inoperable retinal detachment\n* Phthisis bulbi","ALL","18 Years","80 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this study is to demonstrate the safety and efficacy of the corneal collagen crosslinking with riboflavin and ultraviolet A in aim to increase the resistance of the graft used as a support for the Boston keratoprosthesis (KPro) type I against corneal melting (keratolysis or sterile necrosis).",[28],"Corneal Melting in Boston Keratoprosthesis Type I","RECRUITING","2026-04-24",{"date":32,"type":33},"2026-04-28","ACTUAL",{"date":35,"type":33},"2017-01-04",{"date":37,"type":22},"2028-01",{"name":39,"class":40},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER"]