[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coronary-artery-bypass-graft-cabg\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coronary-artery-bypass-graft-cabg":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,51,76,112,138,167,194,223,248,269,292],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100054302","photobiomodulation-in-coronary-artery-bypass-grafting-with-no-touch-vs-conventional-saphenous-vein-harvesting-100054302",false,"NCT07699679","Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.","Impact of Photobiomodulation in Coronary Artery Bypass Surgery: Comparison Between No-Touch and Conventional Saphenous Vein Harvesting Techniques on Clinical Outcomes, Functional Capacity, and Wound Healing: A Randomized Clinical Trial","PHOTON","Inclusion Criteria:\n\n* Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG)\n* Use of the saphenous vein as a graft for myocardial revascularization\n* Ability to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Emergency coronary artery bypass surgery\n* Previous surgery in the lower limb that prevents saphenous vein harvesting\n* Active infection at the surgical site or lower limb\n* Severe peripheral arterial disease in the lower limbs\n* Hemodynamic instability preventing study protocol procedures\n* Participation in another interventional clinical trial that may interfere with the outcomes of this study\n* Patients unable to perform postoperative functional capacity assessments\n* Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy.","ALL","18 Years","75 Years",{"count":21,"type":22},292,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with placebo, conventional harvesting with photobiomodulation, no-touch harvesting with placebo, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.",[28,29,30],"Coronary Artery Disease","Coronary Artery Bypass Graft (CABG)","Surgical Wound Healing",[32,33,34,35,36,37],"Photobiomodulation","Low-Level Laser Therapy","Coronary Artery Bypass Grafting","Saphenous Vein Harvesting","No-Touch Technique","Wound Healing","NOT_YET_RECRUITING","2026-07-08",{"date":41,"type":42},"2026-07-13","ACTUAL",{"date":44,"type":22},"2026-08",{"date":46,"type":22},"2028-03",{"name":48,"class":49},"Federal University of São Paulo","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100642744","early-phase-1-chest-tube-delivered-bupivacaine-to-decrease-postoperative-pain-after-cardiac-surgery-100642744","NCT07643506","Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery","A Randomized Double-Blind Placebo Controlled Trial for Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery: the FREEZE-B Trial","FREEZE-B","Inclusion Criteria:\n\n* Age 18 years or older at the time of consent\n* Scheduled to undergo elective or semi-elective coronary artery bypass graft (CABG) surgery via midline sternotomy\n* Procedure involves the use of a mammary artery graft\n* Capable of providing informed written consent prior to surgery\n* Able to communicate pain scores using a numeric rating scale (NRS)\n\nThese criteria ensure the study population is the clinically relevant group most likely to benefit from the intervention and that participants can provide valid consent and meaningful pain assessments.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to bupivacaine or any amide-type local anesthetic\n* Emergency or urgent cardiac surgery where obtaining consent prior to the procedure is not feasible\n* Inability to communicate pain using numeric rating scale due to cognitive impairment, language barrier, or altered level of consciousness\n* Participation in another interventional clinical trial that may confound pain outcome\n\nThese exclusion criteria are designed to protect participant safety, ensure the validity and interpretability of study outcomes (pain scoring ability), and maintain scientific rigor.",{"count":60,"type":22},60,[62],"EARLY_PHASE1","Background:\n\nAfter heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs. These tubes are often very painful and can limit breathing, coughing, and movement, which necessitates usage of painkiller medication (opioids and non-steroidal anti-inflammatory drugs (NSAIDs)) that have negative side effects and can prolong hospital recovery. Despite this common problem, routine care lacks simple, add-on strategies that directly numb pain at the chest tube sites rather than relying solely on whole-body painkiller medicine.\n\nPurpose:\n\nTo determine whether injecting a long-acting numbing medicine (bupivacaine 0.5%) through chest tubes safely reduces pain and lowers opioid and NSAID use compared with placebo.\n\nObjective:\n\nWith ethics approval, data access, and study procedures already in place before May, the specific objective for this studentship is to collect and analyze data to evaluate the short-term effect of bupivacaine versus placebo on:\n\n* Mean pain scores from initial recovery to chest tube removal\n* Total mean opioid and NSAID use\n\nMethods:\n\nThis single-centre, 1:1 block randomized, double-blind, placebo-controlled trial will enroll 60 adults undergoing coronary artery bypass (procedure to bypass blocked blood vessels supplying heart muscle using healthy blood vessels) at the Foothills Medical Centre. Patients receive either 10 mL bupivacaine 0.5% or normal saline (saltwater placebo) through chest tubes by heart surgeons whenever pain hits ≥3\u002F10 using the Numeric Rating Scale (0 = no pain; 10 = most intense pain), from initial recovery to chest tube removal. Standard pain care will continue for all patients. The study team will record pain scores, opioid and NSAID doses, and any side effects for each group. Interval pain reduction will be measured 30, 60, 120 and 240 minutes post injection. Mean pain reduction and total painkiller use will be compared between the two groups.",[29,65,66],"Chest Tubes","Post Operative Pain Control","2026-06-08",{"date":69,"type":42},"2026-06-11",{"date":71,"type":22},"2026-06-15",{"date":73,"type":22},"2028-06-30",{"name":75,"class":49},"University of Calgary",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":50},"100637800","multimodal-fascial-plane-block-for-postoperative-analgesia-in-isolated-cabg-surgery-100637800","NCT07587320","Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery","Effect of Induction-Time Multimodal Fascial Plane Block on Postoperative Analgesia and Opioid Consumption in Patients Undergoing Isolated Coronary Artery Bypass Grafting: A Prospective Randomized Controlled Trial","BLOCKCABG","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting\n* ASA physical status II-IV\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known coagulopathy or contraindication to regional anesthesia\n* Use of anticoagulant therapy precluding regional block\n* Known allergy to local anesthetics\n* Local infection at planned block sites\n* Chronic opioid use or chronic pain syndrome\n* Emergency surgery\n* Redo sternotomy\n* Severe neurological disorder affecting pain assessment","80 Years",{"count":86,"type":22},56,[25],"Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery.\n\nThis prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting.\n\nPatients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.",[29,90,91],"Postoperative Pain","Sternotomy",[93,94,95,96,97,98,99,100,101],"Parasternal Block","Serratus Anterior Plane Block","Adductor Canal Block","Opioid Consumption","Multimodal Analgesia","Randomized Controlled Trial","Cardiac Surgery","Fascial Plane Block","Coronary Artery Bypass Graft","RECRUITING","2026-05-12",{"date":105,"type":42},"2026-05-14",{"date":107,"type":42},"2026-01-01",{"date":109,"type":22},"2026-09",{"name":111,"class":49},"Saglik Bilimleri Universitesi",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":122,"briefSummary":123,"conditions":124,"keywords":125,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":134,"locationsCount":137},"100616211","aortic-no-touch-vs-partial-aortic-clamping-in-off-pump-cabg-100616211","NCT07302659","Aortic No-Touch vs Partial Aortic Clamping in Off-Pump CABG","Surgical Techniques to Prevent Perioperative Neurologic Complications in Patients Undergoing Coronary Artery Bypass Grafting","PROTECT-CABG","Inclusion Criteria:\n\n* Adult patients (\\>18 years old) with multivessel coronary artery disease who are scheduled to undergo isolated off-pump coronary artery bypass grafting and who provide informed consent to participate in this study.\n\nExclusion Criteria:\n\n* Indications for cardiopulmonary bypass surgery (or no contraindications to on-pump surgery);\n* Great saphenous vein is unsuitable for use as a graft conduit;\n* Subclavian artery stenosis or occlusion, or any contraindication to the use of the internal mammary artery as a graft conduit;\n* History of previous cardiac surgery;\n* Emergency surgery;\n* Inability to apply an aortic clamp due to severe ascending aortic calcification;\n* Expected inability to tolerate MRI or contraindications to MRI (e.g., known intolerance to MRI, an implanted permanent pacemaker, or an anticipated need for permanent pacemaker implantation);\n* Inability to complete neurocognitive assessment due to language barriers or visual\u002Fhearing impairment.",{"count":121,"type":22},380,[25],"To explore surgical strategies that reduce perioperative neurologic complications in cardiovascular surgery, with the aim of improving perioperative outcomes and quality of life while reducing the socioeconomic burden. Specifically:\n\nThis multicenter, randomized controlled clinical trial will evaluate the benefits of a novel aortic no-touch technique in reducing perioperative silent brain infarction(SBI) among patients undergoing surgical treatment for coronary artery disease. The findings are expected to provide a safe and effective myocardial revascularization strategy for individuals at high risk of cerebral ischemia.",[29],[126,127],"coronary artery bypass graft","Silent Brain Infarction","2026-04-09",{"date":130,"type":42},"2026-04-14",{"date":132,"type":42},"2026-03-10",{"date":73,"type":22},{"name":135,"class":136},"China National Center for Cardiovascular Diseases","OTHER_GOV",4,{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":145,"sex":17,"minAge":146,"maxAge":84,"enrollmentInfo":147,"targetDuration":4,"studyType":149,"phases":4,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":50},"100578691","hyperpolarized-13c-pyruvate-mri-and-fdg-pet-in-a-single-exam-for-the-prognosis-of-ischemic-cardiomyopathy-100578691","NCT06814587","Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy","FDG PET-HP MRI","Study Population Description The study population will consist of 12 to 15 human subjects divided into two main groups. The first group includes 6 healthy individuals with a normal left ventricular ejection fraction (LVEF \\> 0.50). The second group comprises 9 patients with advanced ischemic cardiomyopathy (ICM) and a low LVEF (\\\u003C 0.40) who are scheduled for standard-of-care Coronary Artery Bypass Graft (CABG) surgery. The study team will aim to recruit a mixed-sex, age-matched population with equal numbers for all metabolic imaging studies.\n\nIschemic Cardiomyopathy (ICM) Patient Cohort\n\nInclusion Criteria:\n\nMale or Female, age 18-80 years. Patient scheduled for Coronary Artery Bypass Surgery as standard of care therapy per clinical guidelines.\n\nPresence of 1 or more stenotic coronary artery vessels. Left Ventricular Ejection Fraction (LVEF) ≤ 40%, or clinical indication for myocardial viability assessment.\n\nAble to tolerate FDG PET\u002FMRI protocol and preparation (e.g., fasting state, glucose regulation).\n\nMedication use within 24 hours of the scan is allowed and will be reported. Negative pregnancy test for females of childbearing age (on the day of scanning).\n\nNo known contraindications to 3T MRI, SPECT MPI, or FDG PET.\n\nExclusion Criteria:\n\nMale or female, age \\\u003C 18 or \\> 80 years of age. Patients not scheduled for CABG or those without confirmed coronary artery disease (CAD).\n\nHistory of prior myocardial infarction with transmural scar \\> 50% (based on prior imaging or clinical history).\n\nPatient not eligible for 3T MRI (Any condition or device precluding safe MRI e.g., pacemakers, defibrillators, metal implants), SPECT (significant arrhythmias or hemodynamic instability), or FDG-PET (e.g., severely impaired glucose metabolism).\n\nPositive pregnancy test or females currently breastfeeding (on the day of scanning).\n\nSevere renal impairment (GFR \\\u003C 30 mL\u002Fmin) or contraindication to FDG PET tracer.\n\nHistory of uncontrolled diabetes mellitus (HbA1c \\> 9%) or inability to achieve stable glucose levels for FDG PET preparation.\n\nHealthy Volunteer Cohort\n\nInclusion Criteria:\n\nMale or Female, age 18-80 years. No history of coronary artery disease or diabetes. Eligible for 3T MRI, SPECT, and FDG-PET. Negative pregnancy test for females of childbearing age (on the day of scanning).\n\nExclusion Criteria:\n\nHistory of coronary artery disease, diabetes, or other medical conditions deemed exclusionary by the study team.\n\nPositive pregnancy test or females currently breastfeeding (on the day of scanning).\n\nContraindications to MRI (e.g., metallic implants, claustrophobia), SPECT MPI, or FDG-PET.",true,"20 Years",{"count":148,"type":22},15,"OBSERVATIONAL","This prospective, non-blinded, single-center, translational research study aims to validate a multimodal advanced imaging exam for cardiac viability. The protocol utilizes three distinct imaging modalities: Single Photon Emission Computed Tomography Myocardial Perfusion Imaging (SPECT MPI), 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), and Hyperpolarized Carbon-13 (HP-13C) Pyruvate Magnetic Resonance Imaging (MRI). Under this protocol, the SPECT MPI and FDG-PET exams will be used in combination to comprehensively assess myocardial viability. Concurrently, the HP-13C Pyruvate MRI will be utilized to provide additional insights into myocardial metabolism. The study will evaluate healthy volunteers to establish baseline parameters and patients with ischemic cardiomyopathy (ICM) before and after surgical revascularization.",[28,29],[28,153,154,155,156,157],"Hyperpolarized 13C Pyruvate-MRI","FDG-PET","PET-MRI","SPECT-MPI","Myocardial Viability","2026-02-24",{"date":160,"type":42},"2026-02-27",{"date":162,"type":42},"2024-07-01",{"date":164,"type":22},"2026-06-30",{"name":166,"class":49},"University of Texas Southwestern Medical Center",{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":174,"targetDuration":4,"studyType":23,"phases":176,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":50},"100602240","effects-of-emotional-freedom-techniques-on-pain-cardiac-anxiety-and-sleep-quality-in-coronary-artery-bypass-grafting-100602240","NCT07120932","Effects of Emotional Freedom Techniques on Pain, Cardiac Anxiety, and Sleep Quality in Coronary Artery Bypass Grafting","Effects of Emotional Freedom Techniques (EFT) on Pain, Cardiac Anxiety and Sleep Quality in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial","Inclusion Criteria: Patients who are:\n\n* 18 years of age or older,\n* 3 days postoperatively after coronary artery bypass graft surgery,\n* literate,\n* conscious and able to communicate will be included.\n\nExclusion Criteria:\n\n* Patients with speech, hearing, or visual impairments\n* Patients who do not believe in the effectiveness of the procedure due to prejudice will not be included.",{"count":175,"type":22},66,[25],"Objective: To determine the effect of Emotional Freedom Techniques (EFT) on pain, cardiac anxiety and sleep quality in patients undergoing Coronary Artery Bypass Graft (CABG) surgery.\n\nMaterials and Methods: The study will be conducted between 2025 and 2026 as a pretest-posttest, parallel design (1:1) randomized controlled trial. The study population will consist of patients undergoing coronary artery bypass grafting (CABG) at the Kütahya City Hospital Cardiovascular Surgery Department. The sample size was determined to be 66 patients, with 33 patients each in the experimental and control groups.\n\nMeasurement tools include a Personal Information Form, Visual Analog Scale (VAS), Cardiac Anxiety Scale, and Richard Campbell Sleep Scale. Data will be collected through one-on-one patient interviews.\n\nThe researcher has successfully completed a 3.5-hour EFT training program at the Boğaziçi Education Institute. EFT will be administered to the patients by the researcher.\n\nPatients undergoing coronary artery bypass graft surgery at the Cardiovascular Surgery Clinic who volunteer to participate in the study and meet the inclusion criteria will complete the Informed Consent Form, Personal Information Form, Visual Analogue Scale (VAS), Cardiac Anxiety Scale, and Richard-Campbell Sleep Scale. Patients will then be assigned to the experimental or control groups by a person other than the researcher based on the randomization list. Patients in the experimental group will receive EFT in addition to standard cardiovascular surgery clinic procedures, while patients in the control group will receive standard cardiovascular surgery clinic procedures. Data analysis will be conducted using SPSS. The study will be conducted in accordance with the principles of the Declaration of Helsinki.\n\nFindings: The findings of the research will be written after the data to be obtained after the implementation of the research and data collection will be analyzed in the SPSS program.\n\nConclusion: The results of the research will be written by determining the findings after analyzing the data to be obtained after the implementation of the research and data collection in the SPSS program.",[29,179],"Effects of Emotional Freedom Techniques (EFT)",[181,179,182,183,184],"Coronary Artery Bypass Graft Surgery","Pain Management","Anxiety","Sleep","2026-02-19",{"date":187,"type":42},"2026-02-20",{"date":189,"type":22},"2026-04-15",{"date":191,"type":22},"2026-08-15",{"name":193,"class":49},"Hatice Balcı",{"id":195,"slug":196,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":200,"eligibilityCriteria":201,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":84,"enrollmentInfo":202,"targetDuration":4,"studyType":23,"phases":204,"briefSummary":205,"conditions":206,"keywords":209,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":221,"locationsCount":50},"100601933","multisensory-and-cognitive-interventions-in-the-icu-effects-on-health-and-recovery-100601933","NCT07116941","Multisensory and Cognitive Interventions in the ICU: Effects on Health and Recovery","Effects of Multisensory and Cognitive Interventions Applied in the Intensive Care Unit on Physiological, Psychological and Functional Outcomes","MICU-CARE","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Underwent coronary artery bypass grafting (CABG) or other open-heart surgery\n* Admitted to the ICU postoperatively and eligible for early mobilization\n* Hemodynamically stable (within normal blood pressure and heart rate ranges, without inotropic support)\n* Alert and able to communicate\n\nExclusion Criteria:\n\n* Diagnosis of ICU delirium or altered mental status\n* Severe hemodynamic instability\n* Presence of neurological disease or significant cognitive impairment\n* Significant sensory deficits (e.g., severe hearing or vision loss)\n* Known allergy or psychological sensitivity to auditory or olfactory stimuli (e.g., aromatherapy or music)",{"count":203,"type":22},125,[25],"The goal of this clinical trial is to examine the effects of sensory and cognitive stimulation on physiological, psychological, and functional recovery in adult patients after cardiac surgery who are treated in the intensive care unit (ICU). The main questions it aims to answer are:\n\n* Does sensory and\u002For cognitive stimulation reduce anxiety and improve hemodynamic stability in ICU patients?\n* Does it enhance physical function and independence during early rehabilitation in the ICU?\n\nResearchers will compare four groups:\n\n1. Standard care (control),\n2. Cognitive stimulation,\n3. Auditory stimulation (music),\n4. Multisensory stimulation (touch + smell)\n\nto assess which intervention is most effective in improving recovery parameters.\n\nParticipants will:\n\n* Be randomly assigned to one of four groups during early mobilization in the ICU\n* Receive a 30-minute intervention session depending on group assignment\n* Be evaluated for heart rate, blood pressure, oxygen saturation, anxiety (VAS), physical function (PFIT, FIM), and satisfaction before and after the session",[29,207,208],"Cardiac Surgery Subjects","Postoperative Care",[210,211,99,212,183,213,214],"Early Mobilization","Intensive Care Unit","Multisensory Intervention","Non-pharmacological Intervention","Rehabilitation in ICU","2026-02-10",{"date":217,"type":42},"2026-02-12",{"date":219,"type":42},"2025-08-01",{"date":164,"type":22},{"name":222,"class":49},"Abant Izzet Baysal University",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":229,"eligibilityCriteria":230,"healthyVolunteers":11,"sex":231,"minAge":232,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":23,"phases":236,"briefSummary":237,"conditions":238,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":50},"100621232","incentive-spirometry-versus-inspiratory-muscle-training-after-coronary-artery-bypass-grafting-100621232","NCT07367945","Incentive Spirometry Versus Inspiratory Muscle Training After Coronary Artery Bypass Grafting","Effect of Incentive Spirometry Versus Inspiratory Muscle Training on Arterial Blood Gases After Coronary Artery Bypass Grafting","IS\u002F IMT","Inclusion Criteria:\n\n* 45 male patients will be included in this study.\n* Patients with age from 50 to 60 years old (undergoing coronary artery bypass graft surgery) through median sternotomy.\n* Their body mass index from 25 to 29.9 kg\u002Fm2\n* Patients will be alert and able to follow instruction.\n\nExclusion Criteria:\n\n* Who are expected not to be able to conduct or comply with IS and IMT.\n* Patients with cognitive or neurological deficits.\n* Patients with coexisting acute or chronic respiratory disorders.\n* Patients unable to understand or show the proper use of the incentive spirometer and Inspiratory muscle training .\n* Patients who cannot be instructed or supervised to assure appropriate use of the device patients in whom cooperation is absent or patients unable to understand or demonstrate proper use of the devices (inspiratory muscle training and incentive spirometry).\n* Patients who are confused or delirious.\n* Patients undergoing any other surgery along with CABG.\n* Patients undergoing emergency CABG surgery.\n* Chronic obstructive pulmonary disease (COPD), asthma, restrictive lung disease, preoperative major chest infection e.g. pulmonary tuberculosis, chest deformities such as pectus carinatum, pectus excavatum, thoracolumbar scoliosis, diaphragmatic hernias diagnosed on history.","MALE","50 Years","60 Years",{"count":235,"type":22},45,[25],"This study will be conducted to compare between incentive spirometry verses inspiratory muscle training preoperatively on (ABG) after coronary artery bypass graft surgery.\n\nIs there any significant difference of preoperative incentive spirometry verses inspiratory muscle training on Arterial blood gases (ABG) after coronary artery bypass graft surgery?\n\nParticipants will:\n\nGroup A (incentive spirometry group ) Group B (Inspiratory muscle trainer group ) for 5 days before operative Group C (control group) and group a , b will have routinely postoperative",[29],"2026-01-20",{"date":241,"type":42},"2026-01-26",{"date":243,"type":22},"2026-02-01",{"date":245,"type":22},"2027-03-01",{"name":247,"class":49},"Cairo University",{"id":249,"slug":250,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":254,"eligibilityCriteria":255,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":256,"targetDuration":258,"studyType":149,"phases":4,"briefSummary":259,"conditions":260,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":265,"leadSponsor":267,"locationsCount":4},"100617296","saudi-cabg-audit-and-registry-100617296","NCT07316777","Saudi CABG Audit and Registry","Protocol for Development and Implementation of the Saudi CABG Audit and Registry: A Prospective National Clinical Registry","SCAR","Inclusion Criteria:\n\n* Adult patients aged 18 years or older\n* Undergoing isolated CABG\n* Undergoing CABG with concomitant procedures (e.g., valve repair or replacement)\n* Undergoing on-pump, off-pump, minimally invasive, or robotic CABG\n* Procedures performed electively, urgently, or emergently\n\nExclusion Criteria:\n\n* Redo CABG when the primary operative record is not available\n* Patients younger than 18 years",{"count":257,"type":22},3000,"12 Months","The Saudi CABG Audit and Registry (SCAR) is a prospective, multicenter national clinical quality registry designed to systematically collect perioperative and long-term outcome data for all patients undergoing coronary artery bypass grafting (CABG) in Saudi Arabia. The registry will begin with a pilot phase in selected tertiary cardiac centers and will progressively expand to national coverage. SCAR captures detailed information on patient demographics, cardiac status, operative techniques, postoperative outcomes, and 1-year follow-up, including patient-reported quality-of-life measures (EQ-5D and SF-36). The aim is to establish a standardized national platform for benchmarking, quality improvement, and real-world evidence generation to support clinical decision-making and health policy development in cardiac surgery. Data are collected prospectively through secure electronic systems, anonymized before central storage, and analyzed using standardized definitions aligned with international registries such as STS and E-CABG.",[29],"2025-12-18",{"date":263,"type":42},"2026-01-05",{"date":107,"type":22},{"date":266,"type":22},"2027-12-31",{"name":268,"class":49},"King Faisal Specialist Hospital & Research Center",{"id":270,"slug":271,"hasResults":11,"nctId":272,"briefTitle":273,"officialTitle":273,"acronym":274,"eligibilityCriteria":275,"healthyVolunteers":11,"sex":17,"minAge":233,"maxAge":4,"enrollmentInfo":276,"targetDuration":4,"studyType":23,"phases":277,"briefSummary":278,"conditions":279,"keywords":280,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":283,"lastUpdatePostDateStruct":284,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":290,"locationsCount":4},"100603593","investigation-of-the-effect-of-prehabilitation-practice-on-patient-outcomes-in-frail-patients-planned-for-elective-coronary-artery-bypass-graft-100603593","NCT07138534","Investigation of the Effect of Prehabilitation Practice on Patient Outcomes in Frail Patients Planned for Elective Coronary Artery Bypass Graft","ERAS","Inclusion Criteria:\n\n* frail patient\n\nExclusion Criteria:\n\n* frail patient",{"count":60,"type":22},[25],"The basic concept of prehabilitation is to increase the functional capacity of the individual to withstand an expected injury. It embodies the idea of being proactive against the common reactive approach of rehabilitation. While the initial prehabilitation model was limited to physical training, it has now evolved into a multimodal entity that includes nutritional optimisation, psychosocial preparation and smoking cessation in addition to exercise programmes. In the last decade, there has been an increasing effort to coincide prehabilitation with surgery, as surgery is rightly perceived as a stressor for human structural and physiological functions.",[29],[281,282],"frail patients","coronary artery bypass","2025-08-21",{"date":285,"type":42},"2025-08-24",{"date":287,"type":22},"2025-09-01",{"date":289,"type":22},"2025-12-30",{"name":291,"class":49},"Bahçeşehir University",{"id":293,"slug":294,"hasResults":11,"nctId":295,"briefTitle":296,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":17,"minAge":298,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":23,"phases":301,"briefSummary":302,"conditions":303,"keywords":304,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":311,"completionDateStruct":313,"leadSponsor":315,"locationsCount":317},"100595622","investigation-of-the-effects-of-respiratory-muscle-training-combined-with-otago-exercises-in-elderly-patients-undergoing-coronary-artery-bypass-graft-surgery-100595622","NCT07034846","Investigation of the Effects of Respiratory Muscle Training Combined With Otago Exercises in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery","Inclusion Criteria:\n\n* 65 years and older undergoing coronary artery bypass graft surgery\n* Hospital discharge realized (post operative ≥ 2 weeks)\n* No contraindications for exercise training\n* Not concurrently participating in another exercise training program\n* Have the means to enter a home-based rehabilitation program\n* Patients who agree to participate voluntarily will be included in the study program.\n\nExclusion Criteria:\n\n* Cardiovascular instability (aortic dissection, unstable angina pectoris, acute decompensated heart failure, acute pericarditis or myocarditis, severe cardiac arrhythmia, ventricular aneurysm)\n* Uncontrolled hypertension and diabetes mellitus\n* Diagnosed with chronic lung disease\n* Cognitive impairment that prevents them from communicating with the physiotherapist\n* Failure to maintain the exercise training program\n* Patients with severe orthopedic or neurological disorders will not be included.","65 Years",{"count":300,"type":22},28,[25],"A review of the literature suggests that high-intensity intermittent inspiratory muscle training (IMT) combined with the Otago exercise program may provide positive effects on early post-discharge recovery of patients aged 65 years and older undergoing coronary artery bypass graft (CABG) surgery. No studies have yet examined the effects of high-intensity intermittent IMT combined with the Otago exercise program on patients undergoing CABG surgery. This study is the first to evaluate the effects of high-intensity intermittent IMT combined with the Otago exercise program on pulmonary function, functional capacity, muscle strength, functional mobility, balance, anxiety and depression levels, frailty, and quality of life in elderly patients undergoing CABG surgery.",[29],[305,306,307],"Exercise","Inspiratory muscle training","Otago Exercises","2025-06-15",{"date":310,"type":42},"2025-06-24",{"date":312,"type":22},"2025-07-01",{"date":314,"type":22},"2026-07-01",{"name":316,"class":49},"Istanbul University - Cerrahpasa",3]