[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coronary-artery-bypass-graft-surgery-cabg\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coronary-artery-bypass-graft-surgery-cabg":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,80,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100643112","mechanical-power-and-pulmonary-complications-in-cabg-surgery-100643112",false,"NCT07639489","Mechanical Power and Pulmonary Complications in CABG Surgery","Association of Intraoperative Mechanical Power With Postoperative Pulmonary Complications and Prolonged Mechanical Ventilation in Coronary Artery Bypass Graft Surgery","MP-CABG","Inclusion Criteria:\n\n* Age 18 years or older\n* Scheduled for elective, first-time isolated CABG surgery\n* Use of cardiopulmonary bypass (CPB)\n* Intraoperative mechanical ventilation applied under general anesthesia with recordable ventilator data\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency cardiac surgery\n* Off-pump CABG (without CPB)\n* Preoperative requirement for invasive mechanical ventilation\n* Advanced chronic lung disease\n* Incomplete or unreliable intraoperative ventilatory data\n* Intraoperative use of advanced non-standard support (ECMO)","ALL","18 Years",{"count":20,"type":21},110,"ESTIMATED","OBSERVATIONAL","This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative pulmonary complications (PPCs) and prolonged mechanical ventilation in adult patients undergoing elective coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB). Intraoperative ventilatory parameters including tidal volume, respiratory rate, airway pressures, and PEEP will be recorded and used to calculate MP and driving pressure (DP). No additional interventions will be applied beyond standard clinical care.",[25,26,27],"Postoperative Pulmonary Complications","Coronary Artery Bypass Graft Surgery (CABG)","Prolonged Mechanical Ventilation",[29,30],"intraoperative ventilation","lung-protective ventilation","NOT_YET_RECRUITING","2026-06-06",{"date":34,"type":35},"2026-06-10","ACTUAL",{"date":37,"type":21},"2026-06",{"date":39,"type":21},"2026-09",{"name":41,"class":42},"Fusun Gozen","OTHER_GOV",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":43},"100577602","graft-failure-and-consequences-of-coronary-artery-bypass-graft-surgery-100577602","NCT06800430","Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery","Vein Graft Failure and Cardiovascular Consequences of Coronary Artery Bypass Graft Surgery","INCLUSION CRITERIA:\n\nCohort 1: Patients undergoing CABG surgery\n\n* Males and females over 18 years of age\n* Patients undergoing CABG surgery for multivessel coronary artery disease, who receive at least one saphenous vein graft\n\nCohort 2: Patients with symptomatic saphenous vein graft vasculopathy\n\n* Males and females over 18 years of age\n* Patients who underwent CABG surgery ≥ 5 years prior to recruitment for multivessel disease and received 2 or more saphenous vein grafts\n* Referred for invasive coronary angiography due to recurrent symptoms and with a high suspicion of graft vasculopathy\n\nEXCLUSION CRITERIA:\n\n* Patients with a life expectancy of \\\u003C 2 years\n* Renal failure (estimated glomerular filtration rate \\\u003C30 mL\u002Fmin\u002F1.73 m2)\n* Patients on immunosuppressive therapies\n* Females of child-bearing age who are pregnant or breastfeeding,\n* Known allergy or contraindications to iodinated contrast or radiotracer\n* Patients who are unable to tolerate the supine position\n* Patients who are unable to provide informed consent",{"count":52,"type":21},70,"Coronary artery bypass graft (CABG) surgery is the commonest type of heart operation performed. During this, arteries or veins (termed 'grafts') are used to supply blood around blockages within the blood vessels that supply the heart. Unfortunately, these grafts can sometimes fail, and patients can also experience complications like heart attacks and strokes, after surgery. It is known that vein grafts are more likely to narrow over time. Additionally, treating vein graft failure is very challenging, as repeat surgery is riskier and procedures to stent open the veins can also fail. However, it is not fully understood why these complications occur.\n\nIn this study, the investigators will use an imaging technique called a total-body Positron Emission Tomography (PET) scan. This uses special radioactive dyes (radiotracers) to look at what is happening inside vein grafts. With this technique, the investigators will also be able to see what is happening to the heart, brain and wider parts of the body after CABG surgery.\n\nThis study will aim to recruit 70 participants in total (maximum 150). 40 (maximum of 120) of these participants will have recently undergone CABG surgery and received ≥1 vein graft. The remaining 30 will have undergone CABG surgery ≥5 years ago and will have symptoms suggestive of vein graft failure.\n\nThe study will last a total of 36 months and will involve participants undertaking the following assessments:\n\n1. Total-body Positron Emission Tomography and Computed Tomography (PET-CT) scan\n2. Ultrasound scan of the heart (echocardiogram)\n3. A blood test - up to four tablespoons (60 mL) of blood will be taken for immediate testing and the remainder will be stored for future ethically approved studies.",[55,56,57,26],"Coronary Artery Bypass","Graft Failure","Coronary Artery Bypass Graft",[59,60,61,62,63,64,65,66,67,68],"CABG","graft failure","coronary artery bypass","cardiovascular","heart surgery","cardiac surgery","coronary artery bypass graft","cardiovascular disease","heart disease","positron emission tomography","RECRUITING","2026-04-15",{"date":72,"type":35},"2026-04-20",{"date":74,"type":35},"2025-03-28",{"date":76,"type":21},"2027-08-06",{"name":78,"class":79},"University of Edinburgh","OTHER",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":43},"100613218","determining-the-consistency-between-nurses-and-artificial-intelligence-chatgpt-5-in-delivering-scenario-based-discharge-education-to-coronary-artery-bypass-graft-patients-a-methodological-study-100613218","NCT07263724","Determining the Consistency Between Nurses and Artificial Intelligence (ChatGPT-5) in Delivering Scenario-Based Discharge Education to Coronary Artery Bypass Graft Patients: A Methodological Study","CABG-AI-EDU","Inclusion Criteria:\n\n* Patient scenarios representing individuals who have undergone coronary artery bypass graft (CABG) surgery.\n* Scenarios that include demographic, socioeconomic, clinical, and psychosocial information consistent with current literature and clinical guidelines.\n* Scenarios describing patients who underwent median sternotomy and on-pump CABG procedure.\n* Scenarios that include relevant postoperative complications (e.g., delirium, bleeding, wound infection, arrhythmia) and comorbidities (e.g., diabetes, hypertension, COPD).\n* Scenarios that enable both nurse and ChatGPT-5 to prepare discharge education materials under the same standardized framework.\n* Scenarios reviewed and validated by cardiovascular surgery experts and nurse academicians for content validity.\n\nExclusion Criteria:\n\n* Patient scenarios not related to coronary artery bypass graft (CABG) surgery.\n* Scenarios lacking sufficient demographic, clinical, or psychosocial information to prepare individualized discharge education.\n* Scenarios that do not follow the standardized structure of six main domains and twenty-four subtopics.\n* Scenarios with inconsistent or contradictory medical data (e.g., incompatible diagnosis and treatment details).\n* Scenarios not validated by the expert review panel for clinical accuracy and content validity.\n* Scenarios that do not allow comparison between nurse-generated and ChatGPT-5-generated discharge education materials.",true,{"count":89,"type":21},30,"This methodological study aims to determine the level of agreement between nurses and an artificial intelligence system (ChatGPT-4.0) in providing scenario-based discharge education for patients who have undergone coronary artery bypass graft (CABG) surgery. Thirty standardized patient scenarios representing different demographic, clinical, and psychosocial characteristics will be used. For each scenario, both expert nurses and ChatGPT-4.0 will prepare discharge education content based on six main domains and twenty-four subtopics identified from the literature and clinical guidelines. The educational materials will be independently evaluated by two blinded reviewers in terms of content accuracy, completeness, scientific consistency, and clarity of language. Agreement between nurses and AI-generated content will be analyzed using Cohen's Kappa coefficient and Fisher's Exact Test. The findings are expected to provide evidence for the reliability and applicability of AI-assisted discharge education systems in cardiac surgery nursing practice.",[26,92],"Patient Education",[57,94,95],"Discharge Education","Artificial Intelligence","2026-04-01",{"date":98,"type":35},"2026-04-02",{"date":100,"type":21},"2026-07-01",{"date":102,"type":21},"2027-12-01",{"name":104,"class":79},"Hasan Kalyoncu University",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":126,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":43},"100571898","progressive-relaxation-exercises-before-mobilizationeffects-on-pain-anxiety-and-physiologic-parameters-cabg-patients-100571898","NCT06726239","Progressive Relaxation Exercises Before Mobilization:Effects on Pain, Anxiety and Physiologic Parameters CABG Patients","The Effect of Progressive Relaxation Exercises Applied Before Mobilization on Pain, Anxiety and Physiological Parameters in Patients With Coronary Artery Bypass Graft Surgery","Inclusion Criteria:\n\n* Ability to read and write in Turkish,\n* Analgesics given ≥4h before assessment,\n* Conscious and communicative,\n* Elective coronary artery bypass graft surgery planned,\n* Patients undergoing coronary artery bypass graft surgery for the first time were included in the study.\n\nExclusion Criteria:\n\n* Diagnosed with a psychiatric or neurological disorder,\n* Diagnosis of a musculoskeletal condition that could affect mobilization,\n* Patients with hearing and vision loss,\n* Patients participating in another clinical trial during the same period,\n* Patients who developed any complications during the postoperative period were excluded.","35 Years","65 Years",{"count":115,"type":21},68,"INTERVENTIONAL",[118],"NA","This study is planned as a randomized controlled experimental study to determine the effect of progressive relaxation exercises applied before mobilization on pain, anxiety and physiological parameters in patients undergoing coronary artery bypass graft surgery.",[121,122,123,124,26,125],"Pain","Anxiety","Physiological Parameter","Mobilization","PROGRESSIVE MUSCLE RELAXATION EXERCISES",[127,128,122,129,130],"coronary artery bypass graft surgery","pain","progressive relaxation exercise","physiological parameter","2025-06-26",{"date":133,"type":35},"2025-07-01",{"date":135,"type":35},"2024-05-31",{"date":137,"type":21},"2025-06-30",{"name":139,"class":79},"Istanbul University - Cerrahpasa"]