[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coronary-artery-disease-non-left-main\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coronary-artery-disease-non-left-main":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100579286","the-european-bifurcation-club-randomized-trial-of-stepwise-provisional-stenting-versus-drug-coated-balloon-therapy-for-non-left-main-true-coronary-bifurcations-100579286",false,"NCT06822322","The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations","The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations - EBC DCB Study","EBC DCB","Inclusion Criteria:\n\n* True non-left main bifurcation disease with both MV and SB involvement (i.e Medina 1\u002F1\u002F1, 1\u002F0\u002F1, 0\u002F1\u002F1)\n* Bifurcation lesion responsible for an acute or chronic coronary syndrome with at least one of the following:\n\n  * ≥70% angiographic MV and SB diameter stenosis\n  * Positive non-invasive testing for ischaemia\n  * Positive coronary physiology for ischaemia\n* Significant SB as described by diameter stenosis ≥50% and all of the following:\n\n  * SB length ≥73mm\n  * SB diameter ≥2.5mm\n  * Absence of another SB emerging distally from the MV\n  * Non-dominant circumflex artery, if SB is a diagonal branch.\n\nExclusion criteria\n\n* Patients \\\u003C18 years old\n* STEMI \\\u003C48 hours\n* Cardiogenic shock\n* Chronic total occlusion involving target bifurcation vessels\n* In-stent restenosis\n* Patient life expectancy \\\u003C12 months\n* \\>2 other coronary lesions (target or non-target) planned for treatment\n* SYNTAX score \\>32\n* Platelet count ≤50x109\u002Fmm3\n* Left ventricular ejection fraction ≤20%\n* Participation in another investigational drug or device study\n* Patient unable to give informed consent","ALL","18 Years",{"count":20,"type":21},750,"ESTIMATED","INTERVENTIONAL",[24],"NA","Clinical outcomes are worse in patients with coronary artery bifurcation lesions, even if commonly encountered in clinical practice. The use of drug coated balloons within bifurcation lesions offers the acute advantage of a more straightforward procedure, without recrossing and deformation of a stent. Thus, the primary objective of this study is to determine if Drug Coated Balloon treatment of non-left main true coronary artery bifurcation lesions is non-inferior (similar) to a provisional strategy with Drug Eluted Stent deployment.",[27,28],"Coronary Artery Disease (non-left Main)","Coronary Bifurcation Lesion",[30,31,32],"non-left coronary bifurcation","drug coated balloon","drug eluted stent","NOT_YET_RECRUITING","2025-02-13",{"date":36,"type":37},"2025-02-14","ACTUAL",{"date":39,"type":21},"2025-05",{"date":41,"type":21},"2035-08",{"name":43,"class":44},"Ceric Sàrl","INDUSTRY"]