[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"corticosteroid-injection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:corticosteroid-injection":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100608995","phase-2-comparison-of-submucosal-dexamethasone-and-methylprednisolone-in-postoperative-sequelae-of-parasymphsis-fractures-100608995",false,"NCT07208799","Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures","Comparison of Effectiveness of Submucosal Dexamethasone and Methylprednisolone in Management of Postoperative Sequelae in Mandibular Parasymphysis Fractures","Inclusion Criteria:\n\n1. Patients aged 18 to 40.\n2. Both Gender.\n3. Fracture less than a week old.\n4. Isolated mandibular parasymphysis fractures.\n\nExclusion Criteria:\n\n* 1\\. Immunocompromised patients (due to increased risk of infection and complications).\n\n  2\\. Patients experiencing acute pain from conditions such as pulpitis, abscesses, or other acute infections (to ensure that acute pain does not confound the study results).\n\n  3\\. Patients reporting hypersensitivity to steroids (to avoid adverse reactions).\n\n  4\\. Patients taking or requiring prophylactic antibiotics or anti-inflammatory drugs before surgery (to prevent confounding effects on study outcomes).\n\n  5\\. Patients with a history of systemic steroid administration for 15 days (as this could affect the study's outcomes).\n\n  6\\. Patients with chronic pain problems or mental disorders (to maintain consistency in response to treatment).\n\n  7\\. Patients with comminuted fractures (to maintain consistency in fracture type).\n\n  8\\. Pregnant or lactating women (to avoid potential risks to the fetus and nursing infant).\n\n  9\\. Smokers who smoke at least 10 cigarettes per day for 2 years (to minimize the impact of smoking on healing and recovery).\n\nria:","ALL","18 Years","40 Years",{"count":20,"type":21},72,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.",[27,28,29,30],"Mandible Fracture","Edema Face","Pain Management","Corticosteroid Injection",[32,33,34,35,36,37],"mandible fracture","edema","pain","submucosal","dexamethasone","methylprednisolone","RECRUITING","2026-04-02",{"date":41,"type":42},"2026-04-06","ACTUAL",{"date":44,"type":42},"2026-01-03",{"date":46,"type":21},"2026-12-01",{"name":48,"class":49},"Nishtar Medical University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":50},"100553873","is-adding-extracorporeal-shock-wave-therapy-to-physiotherapy-and-corticosteroid-injection-beneficial-for-frozen-shoulder-100553873","NCT06491745","Is Adding Extracorporeal Shock Wave Therapy to Physiotherapy and Corticosteroid Injection Beneficial for Frozen Shoulder","Is Adding Extracorporeal Shock Wave Therapy to Physiotherapy and Corticosteroid Injection Beneficial for Frozen Shoulder?","Inclusion Criteria:\n\n1. age between 20 to 80 years old;\n2. shoulder pain for ≥ 1 month;\n3. \\> 30% loss of passive range of motion (ROM) of the affected shoulder in external rotation and\u002For abduction, comparing with the sound side;\n4. pain visual analog scale on maximal passive external rotation or abduction \\> 4;\n5. showing willing to receive ESWT, shoulder joint injection, and attend regular physical therapy programs for 8 weeks.\n\nExclusion Criteria:\n\n1. severe systemic disorders including cancer, stroke, or cardiopulmonary diseases;\n2. uncontrolled DM;\n3. rotator cuff tear or calcification of the affected shoulder;\n4. fracture, dislocation, or arthritis of the shoulder due to rheumatic disorders;\n5. a history of drug allergy to local anesthetics or corticosteroids;\n6. pregnancy;\n7. receiving ESWT, corticosteroid joint or bursa injection of the affected shoulder during the preceding three months","20 Years","80 Years",{"count":61,"type":21},94,[63],"NA","Frozen shoulder, or adhesive capsulitis of the shoulder, is a common clinical problem characterized by pain, loss of both passive and active range of motion (ROM) of glenohumeral joint (GHJ), leads to functional limitation, and reduces quality of life. Primary frozen shoulder occurs without any obvious connection to any other condition, and secondary frozen shoulder is related to some medical problems, such as an injury, inflammatory, immunological, and endocrine conditions, or surgery of the shoulder. The prevalence of frozen shoulder is 2%-5% in general population, usually between 40 to 60 years old, and more in female. Diabetes patients have more chance of developing frozen shoulder than general population and the prevalence was 13.4%.\n\nFrozen shoulder is clinically divided into 3 overlapping phases. The painful freezing phase has a duration of 10 to 36 weeks and is characterized by pain and stiffness around the shoulder, which may worsen at night. The frozen phase is characterized by restricted ROM with a gradual relief of pain, which occurs at 4 to 12 months. The thawing phase with spontaneous improvement in the ROM takes 12 to 42 months. .Although frozen shoulder is a self-limited condition, the recovery may be slow and incomplete.\n\nTreatment of frozen shoulder consists of physiotherapy, oral medication (nonsteroidal anti-inflammatory drugs or corticosteroid), intra-articular corticosteroid injection, hydrodilatation, suprascapular nerve block, mobilization, manipulation under anesthesia, and operative intervention (arthroscopic release or open release). Because of the uncertainty of the efficacy and risk of surgical treatment, nonsurgical treatments are more likely chosen by patients. Among them, intra-articular steroid injection and physical therapy are commonly used nonsurgical treatments and have shown some benefits. .Because the clinical picture of frozen shoulder may be similar to, or combining with chronic subacromial bursitis, especially in the freezing stage, concomitant subacromial\u002Fsubdeltoid (SASD) bursa injection may be needed for treatment of frozen shoulder. In addition, the 3 stages of frozen shoulder often overlap and the clinical symptoms of patients are complex, adjuvant therapy is often needed throughout the course of treatment. Even after physical therapy (PT) and corticosteroid injection, mild to moderate contracture, especially external rotation, abduction, and internal rotation may still be present.\n\nOver the past few years new evidence has emerged on the effectiveness of extracorporeal shock wave therapy (ESWT) in the treatment of many musculoskeletal disorders. Briefly, ESWT has been shown to promote neovasculization, amplify growth factor and protein synthesis, increase of pain inhibiting substance, alteration of pain receptor neurotransmission, and intensification of tissue regeneration. Furthermore, ESWT can produce a cavitation effect between tissues, cause intertissue release, promote the separation of adhesion, and release the adhesive tissue. Because of its analgesic, anti-fibrotic, and anti-inflammatory effect, application of ESWT as main treatment or an adjunct to other interventions has been tried. Knoblock et al found that focused ESWT can reduce pain in painful nodules in Dupuytren's disease; in a randomized controlled trial Chen et al showed focused ESWT was superior to oral corticosteroid for frozen shoulder, although oral corticosteroid is not commonly prescribed for patients with frozen shoulder. Vahdatpour compared ESWT with sham ESWT on treatment of frozen shoulder after 40mg triamcinolone intra-articular injection, and found that ESWT group seemed to have positive effects on treatment, and quicker return to daily life. Another two studies investigating application of radial shock wave to patients with frozen shoulder showed improvement of ROM, even for diabetic patients. A systemic review and meta-analysis also showed ESWT seems beneficial to patients with frozen shoulder and could be used as an adjunct therapy to routine treatments. However, the authors mentioned that the quality of the included randomized controlled trials were hampered by significant heterogeneity regarding long-term analgesia and joint ROM.\n\nBecause the effect of ESWT against frozen shoulder has not been well established, we aim to investigate whether adding ESWT to corticosteroid injection and routine PT beneficial for patients with frozen shoulder? We hypothesize that ESWT would be a positive adjunctive therapy in the treatment of frozen shoulder.",[66,30,67,68,69],"Frozen Shoulder","Physical Therapy","Extracorporeal Shock Wave Therapy","Rehabilitation",[71,72,73,74,75],"Frozen shoulder","corticosteroid injection","physical therapy","extracorporeal shock wave therapy","rehabilitation","2025-12-22",{"date":78,"type":42},"2025-12-30",{"date":80,"type":42},"2024-08-01",{"date":82,"type":21},"2028-12-31",{"name":84,"class":49},"Shin Kong Wu Ho-Su Memorial Hospital",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":59,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":101,"overallStatus":109,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":50},"100602184","one-cause-of-heel-pain-is-plantar-fasciopathy-pf-in-most-cases-a-heel-spur-is-frequently-present-alongside-pf-we-aim-to-evaluate-the-efficacy-of-corticosteroid-injection-and-radiofrequency-ablation-along-with-tissue-elasticity-assessed-by-ultrasound-in-patients-with-chronic-pain-6-months-100602184","NCT07120204","One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).","Evaluation of Radiofrequency Thermocoagulation Versus Corticosteroid Injection in Patients With Chronic Calcaneal Spur Related Plantar Fasciopathy Using Elastography and Foot Function Index","Inclusion Criteria:\n\n1. Patients with chronic (≥ 6 months) plantar fasciopathy\n2. NRS score ≥ 4\n3. Presence of a calcaneal spur detected by ultrasound (USG) or direct radiography\n4. At least one of the following treatments has been administered:\n\n   * Home exercise program\n   * Physiotherapy\n   * Orthosis\u002Fprosthesis\n   * NSAIDs\n   * Night splint\n   * Kinesio taping\n   * Corticosteroid injection\n   * Extracorporeal shock wave therapy (ESWT)\n\nExclusion Criteria:\n\n1. History of calcaneal trauma\u002Ffracture\n2. Previous radiofrequency ablation (RFA) treatment\n3. Patients with seronegative spondyloarthropathy\n4. Inflammatory or degenerative arthropathies\n5. Presence of diabetes\n6. Pregnancy\n7. History of cancer\n8. Peripheral neuropathy or ischemia\n9. Open wound or signs of infection at the procedure site\n10. Evidence of systemic infection\n11. Patients using anticoagulant or antiplatelet agents\n12. Presence of an intracardiac defibrillator or pacemaker\n13. Patients with tarsal tunnel syndrome\n14. Patients who have received ESWT and\u002For corticosteroid injection within the last 3 months\n15. Presence of heel pain due to lumbar radiculopathy",{"count":93,"type":21},50,[63],"Heel pain is common among adults. One cause of heel pain is plantar fasciopathy (PF). In most cases, a heel spur, a bony prominence that extends into the plantar fascia, is frequently present alongside PF. First-line treatments include pain-relieving drugs, home exercises, heel support peds, and physical therapy. However, some patients can't get relief from these therapies, and the pain persists beyond six months. This situation is referred to as refractory chronic PF. Local treatments applied via skin puncture such as anti-inflamtory injection and destruction of nerves carrying pain signals to brain are warranted in these cases. We aim to evaluate the efficacy of corticosteroid injection and radiofrequency ablation, along with tissue elasticity assessed by ultrasound, in patients with chronic pain (≥6 months).\n\nThe goal of this clinical trial is to determine which treatment-corticosteroid injection or radiofrequency thermal thermocoagulation-is more effective for treating plantar fasciopathy in adults. It will also learn about the effects of the treatments on the properties of the heel tissue using ultrasound. The main questions it aims to answer are:\n\nDo corticosteroid injections and radiofrequency thermal thermocoagulation have the same efficacy on pain and functionality for both short- and long-term? Do corticosteroid injections and radiofrequency thermal thermocoagulation similarly affect heel tissue? The researchers will investigate which of the corticosteroid injection and radiofrequency thermocoagulation is more effective for",[97,98,30,99,100],"Plantar Fasciopathy","Chronic Pain","Radiofrequency Ablation","Elasticity Imaging Techniques",[102,103,104,105,106,107,108],"plantar fasciopathy","plantar fasciitis","randomized","radiofrequency thermal coagulation","RF","shear wave","elastography","NOT_YET_RECRUITING","2025-08-06",{"date":112,"type":42},"2025-08-13",{"date":114,"type":21},"2025-08-15",{"date":116,"type":21},"2026-08-15",{"name":118,"class":49},"TC Erciyes University"]