[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cough-severity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cough-severity":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,52,88],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100515299","validation-of-the-c-mo-system---cough-monitoring-100515299",false,"NCT05989698","Validation of the C-mo System - Cough Monitoring","C-mo_01","Inclusion Criteria:\n\n* Patients aged 2 years or older;\n* Patients with symptoms\u002Fcomplaints of cough;\n* Signed Informed Consent (age ≥ 18 years), signed Informed Consent from the parents\u002Flegal representative and the patient (16 and 17 years), or signed Informed Assent and Consent (5 years ≤ age ≤ 15 years).\n\nExclusion Criteria:\n\n* Presence of musculoskeletal (e.g., severe scoliosis), neurological (e.g., post stroke), cardiac (e.g., unstable angina), cognitive (e.g., dementia) changes, or other significant conditions that hinder the participants from collaborating in the collection of data.\n* Damaged\u002Fweakened skin at the C-mo wearable device's placement area (epigastric region).\n* Absence of Informed Consent and\u002For Assent, as applicable.","ALL","2 Years",{"count":19,"type":20},300,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical study is to validate C-mo System's ability to automatically detect and characterise cough, in patients over 2 years old with cough as a key or refractory symptom.\n\nThe main questions it aims to answer are:\n\n1. Can C-mo System detect cough events? (automatic cough detection)\n2. Can C-mo System characterise cough events? (calculation of cough intensity, identification of cough type and presence of wheeze in detected coughs)\n\nParticipants will be asked to:\n\n* Wear the C-mo Wearable device for 24 hours (1 day);\n* Complete a diary with relevant activities throughout the monitoring period;\n* Fill-out questionnaires related to coughing frequency and intensity, usability of the device, and impact of cough on quality of life.",[26,27,28,29,30,31,32,33],"Cough","Asthma","Chronic Obstructive Pulmonary Disease","Gastro Esophageal Reflux","Idiopathic Pulmonary Fibrosis","Cough Frequency","Cough Severity","Coughing",[35,36,37,38],"Cough monitoring","Cough detection","Cough assessment","C-mo","RECRUITING","2026-04-02",{"date":42,"type":43},"2026-04-08","ACTUAL",{"date":45,"type":43},"2023-12-11",{"date":47,"type":20},"2026-09",{"name":49,"class":50},"Cough Monitoring Medical Solutions","INDUSTRY",8,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":21,"phases":64,"briefSummary":65,"conditions":66,"keywords":71,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":87},"100619209","effect-of-cuff-pressure-assessment-methods-on-postoperative-complications-in-breast-surgery-100619209","NCT07341646","Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery","The Effect of Endotracheal Tube Cuff Pressure Assessment Methods on Postoperative Complications in Patients Undergoing Elective Breast Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Female patients aged 18 to 65 years.\n* Patients classified as American Society of Anesthesiologists (ASA) physical status I, II, or III.\n* Patients scheduled for elective breast surgery requiring general anesthesia and endotracheal intubation.\n* Patients who provide voluntary written informed consent to participate.\n\nExclusion Criteria:\n\n* Patients with a history of Chronic Obstructive Pulmonary Disease (COPD) or an asthma attack within the last 6 months.\n* Presence of preoperative sore throat, hoarseness, or cough.\n* Patients with predicted difficult intubation or those who are difficult to intubate.\n* Patients with communication difficulties that prevent accurate assessment of symptoms.\n* Patients whose surgery duration exceeds 3 hours.\n* Patients older than 65 years.","FEMALE","18 Years","65 Years",{"count":63,"type":20},90,[23],"Endotracheal intubation is a standard procedure used to secure the airway during general anesthesia. A key component of the breathing tube is the \"cuff,\" a balloon-like device that is inflated to seal the airway and prevent aspiration. However, if the pressure within this cuff is too high, it can restrict blood flow to the tracheal lining, leading to complications such as postoperative sore throat, hoarseness, and difficulty swallowing (dysphagia).\n\nCurrently, there are various methods to monitor and adjust this pressure. In many clinical practices, the pressure is adjusted subjectively or checked only once at the beginning of the surgery. These methods may allow pressure to exceed safe limits (typically 20-30 cmH₂O) or fluctuate during the procedure, potentially causing tissue irritation. This randomized controlled trial aims to compare three different methods of assessing and maintaining endotracheal tube cuff pressure to determine which is most effective at reducing postoperative complications. The study focuses on women undergoing elective breast surgery, a group chosen because the surgery typically lasts 1-3 hours and does not involve major changes in head and neck position, allowing for a clear assessment of the cuff pressure methods.\n\nParticipants will be randomly assigned to one of three groups:\n\n* Continuous Monitoring Group: Cuff pressure is monitored continuously using a pressure indicator and maintained within the 20-30 cmH₂O range throughout the surgery.\n* Manometer Group: Cuff pressure is measured and set to 20-30 cmH₂O using a manual manometer once, immediately after intubation.\n* Control Group (Minimal Occlusive Volume): The cuff is inflated with the minimum amount of air required to prevent an air leak, without using a pressure gauge.\n\nResearchers will assess patients for sore throat, cough, hoarseness, and swallowing difficulties at 0, 1, 12, and 24 hours after surgery to identify the safest and most comfortable method for airway management.",[67,68,69,70,32],"Airway Complications","Postoperative Sore Throat","Hoarseness","Dysphagia",[72,73,74,68,67,75],"Continuous Cuff Pressure Monitoring","Manometer","Endotracheal Tube Cuff Pressure","Intubation Safety","NOT_YET_RECRUITING","2026-01-14",{"date":79,"type":43},"2026-01-15",{"date":81,"type":20},"2026-03-01",{"date":83,"type":20},"2027-06-01",{"name":85,"class":86},"Izmir Katip Celebi University","OTHER",1,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":4,"enrollmentInfo":95,"targetDuration":97,"studyType":98,"phases":4,"briefSummary":99,"conditions":100,"keywords":104,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":87},"100583583","cough-and-hemorrhoids-100583583","NCT06878209","Cough and Hemorrhoids","Is Cough a Predisposing Factor for Hemorrhoids? A Prospective, Analytical Study","Inclusion Criteria:\n\n1. Being 18 years of age or older\n2. Speaking and understanding Turkish\n3. To be mentally and cognitively capable of understanding the questions asked\n4. To agree to participate in the research\n5. individuals diagnosed with hemorrhoidal disease\n\nExclusion Criteria:\n\n1. Those with existing proctologic disease other than hemorrhoidal disease and pelvic floor disease\n2. Patients with previous surgery for hemorrhoidal disease\n3. Patients with hemorrhoidal disease caused by portal hypertension\n4. Patients during pregnancy and diagnosed with postpartum hemorrhoidal disease\n5. those with benign prostatic hyperplasia or neurogenic bladder that may cause increased intra-abdominal pressure",{"count":96,"type":20},134,"1 Day","OBSERVATIONAL","The aim of the study is to investigate the relationship between hemorrhoids and cough by assessing the symptoms, duration, and severity of cough in patients who will present to the general surgery outpatient clinic of Muğla Education and Research Hospital (MERH) with symptoms such as bleeding, pain, itching, fecal leakage, prolapse, and mucus discharge. These patients will be diagnosed with hemorrhoidal disease through rectal examination to detect anal pathology and will be graded according to mucosal prolapse. Our study will aim to determine whether cough is a predisposing factor for hemorrhoids by evaluating the presence, duration, and frequency of cough symptoms in patients with hemorrhoids. The study will be designed as a cross-sectional, analytical, and descriptive study. Between March 2025 and June 2025, patients with newly diagnosed hemorrhoids who will present to the MEAH General Surgery Outpatient Clinic will undergo physical examinations and will be assessed for cough symptoms. Evaluations will include height and weight measurements, the Leicester Cough Questionnaire, the Cough Visual Analog Scale (VAS) questionnaire, duration of cough (categorized as acute if shorter than 4 weeks, or chronic if longer than 4 weeks), timing of cough (day, night, or all day), comorbidities (such as COPD, asthma, chronic bronchitis, interstitial lung disease, idiopathic pulmonary fibrosis, and others), and smoking history (active, former, or never smoked). The primary endpoint will be to compare the relationship between the severity of hemorrhoids and the duration and frequency of cough in patients with both conditions. The secondary endpoint will be to compare the grade of hemorrhoids with comorbid chest diseases in these patients. The tertiary endpoint will be to compare the degree of hemorrhoids with the smoking history of patients who have both hemorrhoids and cough.",[101,26,102,31,32,103],"Hemorrhoid","Cough Duration","Hemorrhoids, Internal",[105],"cough, hemorrhoid","2025-05-08",{"date":108,"type":43},"2025-05-11",{"date":110,"type":43},"2025-03-14",{"date":112,"type":20},"2025-10-14",{"name":114,"class":86},"Muğla Sıtkı Koçman University"]