[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"crc-screening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:crc-screening":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100637188","evaluation-of-gixams-efficacy-predicting-the-presence-of-advanced-and-non-advanced-colorectal-neoplasia-in-a-fit-negative-population-100637188",false,"NCT07623902","Evaluation of Gixam's Efficacy Predicting the Presence of Advanced and Non-advanced Colorectal Neoplasia in a FIT Negative Population","Inclusion Criteria:\n\n1. Participants aged ≥45 - ≤84 years.\n2. Able to provide a signed informed consent.\n3. Considered by a physician or healthcare provider as being of 'average risk' for CRC.\n4. Scheduled for a screening colonoscopy at investigation site.\n\nExclusion Criteria:\n\n1. Undergoing colonoscopy for investigation of symptoms.\n2. Has undergone colonoscopy within preceding nine (9) years except for a failed colonoscopy due to poor bowel preparation. Failed colonoscopy must have been within the past year and without therapeutic intervention.\n3. Positive FIT or Fecal Occult Blood Test (FOBT) result within the preceding eleven (11) months.\n4. Has completed Cologuard, Sheild, ColoSense or Epi proColon testing within the preceding three (3) years.\n5. History of colorectal cancer.\n6. Family history of colorectal cancer, defined as having one or more first- degree relatives (parent, sibling, or child) with CRC at any age.\n7. Participant has a diagnosis or medical \u002F family history of any of the following conditions, including:\n\n   * Familial adenomatous polyposis (also referred to as \"FAP\", including attenuated FAP and Gardner's syndrome)\n   * Hereditary non-polyposis CRC syndrome (also referred to as \"HNPCC\" or \"Lynch Syndrome\")\n   * Other hereditary cancer syndromes including but not limited to Peutz-Jeghers Syndrome, MYH-Associated Polyposis (MAP), Turcot's (or Crail's) Syndrome, Cowden's Syndrome, Juvenile Polyposis, Neurofibromatosis, or Familial Hyperplastic Polyposis.\n8. Participant has a diagnosis or personal history of inflammatory bowel disease (IBD) including chronic ulcerative colitis and\u002For Crohn's disease.\n9. Participants with a disability to extend their tongue.\n10. Participants with tongue tremor.\n11. Participants with tongue piercing.\n12. Participants that had a dental visit in the 7 days prior to the Gixam test.\n13. Participants that have taken antibiotics or anti-fungal medications in the 14 days prior to the Gixam test.\n14. Participants that have taken anti-inflammatories or probiotics in the 14 days prior to the Gixam test.\n15. Participant is pregnant.\n16. Participant has any condition that in the opinion of the Investigator should preclude participation in the study.","ALL","45 Years","84 Years",{"count":19,"type":20},1436,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn if the Gixam device effectively identifies persons with pre-cancer or cancer in the colon and rectum in adults aged 45-84 that are of average risk to develop colorectal cancer and have received a negative result on a Fecal Immunochemical Test (FIT). The main questions it aims to answer are:\n\n1. Is the Gixam Device effective in identifying persons with pre-cancer or cancer in the colon and rectum that have received a negative FIT result?\n2. Is the use of the Gixam device safe?\n\nGixam test result will be compared to the findings of a standard of care screening colonoscopy.\n\nStudy participants will:\n\n1. Undergo the Gixam test\n2. Take a FIT at home and ship to a laboratory.\n3. Undergo a standard of care screening colonoscopy.",[26,27],"CRC Screening","Microbiome","RECRUITING","2026-05-28",{"date":31,"type":32},"2026-06-03","ACTUAL",{"date":34,"type":32},"2026-05-18",{"date":36,"type":20},"2026-12-31",{"name":38,"class":39},"Jubaan Ltd.","INDUSTRY",5,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":71},"100612540","feasibility-of-a-multi-channel-intervention-to-promote-colorectal-cancer-screening-among-american-indians-in-oklahoma-100612540","NCT07254910","Feasibility of a Multi-Channel Intervention to Promote Colorectal Cancer Screening Among American Indians in Oklahoma","YVONNE","Inclusion Criteria:\n\n* Age 45-75 Live within IHS Clinton Service Unit catchment area Fluent in English and read at or above 6th grade level Self report as American Indian or have CDIB\n\nExclusion Criteria:\n\n* Self report up to date with CRC screening FIT within 1 year","75 Years",{"count":50,"type":20},150,[23],"The Accelerating Colorectal Cancer Screening and follow-up through Implementation Science (ACCSIS) Program addresses major regional CRC screening disparities among AI in Oklahoma. The investigators are engaged in a participatory and collaborative effort with Tribal Nations, Area Indian Health Boards, and Indian Health Service (IHS) healthcare facilities. The overall objective of this proposal is to leverage these relationships and examine the feasibility of co-developing and disseminating a v-TCHE as part of a multi-channel communication intervention. To achieve this objective, the investigators have partnered with IHS Clinton Service Unit, which serves members of the Cheyenne and Arapaho Tribes. The intervention will be disseminated across two channels: (1) Social Media (i.e., accessed via online study adverts) and (2) Clinic (i.e., direct messaging to patients via a study link in a SMS text). Across both channels, the investigators will examine reach of the intervention and its potential efficacy via a randomized controlled trial. Once participants click on the study link they will be randomized 1:1 to one of two intervention conditions: (1) watch a Narrative Testimonial Video of a real-life Tribal community health educator (control) or (2) an interaction with a v-TCHE. Participants will then complete a post-intervention survey, in which they can click to order a FIT kit afterwards.",[26,54],"CRC (Colorectal Cancer)",[56,57,58,59,60],"colorectal screening","virtual clinician","multi-channel communication","tribal outreach","Tribal Nations","2026-04-22",{"date":63,"type":32},"2026-04-23",{"date":65,"type":20},"2026-05-30",{"date":67,"type":20},"2026-09-30",{"name":69,"class":70},"University of Oklahoma","OTHER",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":48,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":71},"100601851","improving-rates-of-diagnostic-colonoscopy-in-native-americans-100601851","NCT07115875","Improving Rates of Diagnostic Colonoscopy in Native Americans","Improving Rates of Diagnostic Colonoscopy in Native Americans Through a Culturally Sensitive Digital Outreach Intervention","YVONNE-DX","Inclusion Criteria:\n\n* Age 45-75\n* Live in Oklahoma\n* Fluent in English\n* Have access to email\n* Identify as Native American or have a Certificate of Degree of Indian Blood\n\nExclusion Criteria:\n\n\\-",{"count":81,"type":20},164,[23],"Colorectal cancer (CRC) is the second-leading cause of cancer death in both men and women in the United States. Compared to national averages, Native Americans (NA) endure a disproportionate burden of CRC incidence and CRC-specific mortality. The long-term goal of this collaboration is to enhance health equity through the reduction of CRC disparities in morbidity, mortality, stage-at-diagnosis, and survival among NA. To do so, the primary focus of these efforts has been to improve processes that increase uptake of home stool screening. The overall objective is to leverage these relationships and infrastructure to now focus on improving rates of timely diagnostic colonoscopy follow up after an abnormal home stool screening.",[26,54],[86,87,88],"Mobile Health Technology","Telehealth","Digital Outreach","NOT_YET_RECRUITING","2025-09-24",{"date":92,"type":32},"2025-09-30",{"date":94,"type":20},"2025-12",{"date":96,"type":20},"2026-12",{"name":69,"class":70}]