[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"critical-care-medicine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:critical-care-medicine":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100632214","up-study---decipher-persistent-critical-illness-through-in-deep-clinical-phenotyping-100632214",false,"NCT07510776","UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.","UPSt_UCI","Inclusion Criteria:\n\n* Adult patients aged 18 years or older;\n* ICU length of stay equal to or greater than 5 days.\n\nExclusion Criteria:\n\n* Patients with an ICU stay \\\u003C 5 days;\n* Patients discharged from the ICU early due to lack of ward availability, rather than clinical recovery;\n* Patients who do not survive the early phase of critical illness (i.e., early ICU deaths).","ALL","18 Years",{"count":19,"type":20},7000,"ESTIMATED","OBSERVATIONAL","Persistent Critical Illness (PCI) is a condition that affects some patients who remain in the Intensive Care Unit (ICU) for a long time, usually more than 10-14 days. It is estimated to occur in 5-20% of critically ill patients. A recent Portuguese study found that more than 14% of ICU patients stayed longer than 14 days. PCI is often associated with ongoing need for life support, such as mechanical ventilation or medications to maintain blood pressure. However, patients may also experience severe muscle weakness, repeated infections, or other complications, which makes this group very diverse.\n\nOne of the main risk factors for prolonged ICU stay is sepsis, a severe infection that affects the whole body. Other factors-such as prior health conditions, use of corticosteroids, sedation practices, early versus late mobilization, fluid and antibiotic management, and delirium treatment-may also influence the development and course of PCI.\n\nThis study aims to identify different clinical patterns (\"clusters\") among critically ill patients who remain in the ICU for more than 10 days. Patients will be followed until hospital discharge, and up to one year if data are available. Understanding these different patterns will help develop more personalized and effective care strategies for each patient profile.\n\nThe study is a multicenter retrospective cohort including adult patients (≥18 years) admitted to participating ICUs for more than 5 days between 2021 and 2023. Data collected will include demographic, clinical, and laboratory information, details of organ support (such as mechanical ventilation or vasopressors), medications, nutrition, and rehabilitation practices.\n\nStatistical and machine learning methods will be used to identify groups of patients with similar clinical trajectories and to assess how these groups are related to outcomes such as survival, recovery of organ function, or long-term disability.\n\nExpected results are the identification of distinct clinical clusters of PCI that combine clinical and laboratory data, and the development of tailored management strategies to improve recovery and outcomes for patients with PCI.",[24,25,26,27,28],"Critical Illness","Recovery Outcomes","Critical Care, Intensive Care","Critical Care","Critical Care Medicine",[30,31,24],"Persistant Critical Illness","Critical care","RECRUITING","2026-04-08",{"date":35,"type":36},"2026-04-13","ACTUAL",{"date":38,"type":36},"2025-01-13",{"date":40,"type":20},"2027-12-31",{"name":42,"class":43},"Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa","NETWORK",7,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":56,"studyType":21,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":76},"100598343","pediatric-intensive-care-transport-registry-100598343","NCT07070258","Pediatric Intensive Care Transport Registry","PIT Registry","Inclusion Criteria:\n\n* Critically ill children aged at least 27 days and a corrected gestational age of over 41 weeks AND\n* Maximum age of 17 years AND\n* Interhospital transport AND\n* Critical care transport by a dedicated critical care transport team using an intensive care ambulance (Type C vehicle) or an air ambulance OR\n* The transport was accompanied by a specialist in intensive care or emergency medicine. OR\n* The in-hospital destination of the transport is a critical care area, such as an intensive care unit, a trauma room, a resuscitation area, an operating theatre, an emergency imaging procedure or an emergency intervention.","27 Days","17 Years",{"count":55,"type":20},1000,"1 Day","The aim is to establish a nationwide registry for pediatric intensive care transports in Germany. The project aims to describe and analyse the need for, and current practice of, specialised transports. These data could then be used for future demand planning.",[28,59,60],"Transportation of Patients","Pediatrics",[62,63,64,65],"intensive care transport","critical care transport","pediatrics","registry","2025-07-16",{"date":68,"type":36},"2025-07-20",{"date":70,"type":36},"2024-11-25",{"date":72,"type":20},"2029-12-31",{"name":74,"class":75},"Philipps University Marburg","OTHER",2,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":109},"100581954","evaluating-the-clinical-effectiveness-of-endotracheal-tube-position-anomaly-alerting-system-100581954","NCT06857019","Evaluating the Clinical Effectiveness of \"Endotracheal Tube Position Anomaly Alerting System\"","ETPAAS-1","Inclusion Criteria:\n\n* Patients admitted to the intensive care unit\n* At least 18 years old\n\nExclusion Criteria:\n\n* Patients disagree to participate in the study",{"count":85,"type":20},200,"INTERVENTIONAL",[88],"NA","The goal of this clinical trial is to determine whether the Endotracheal Tube Position Anomaly Alerting System (ETPAAS) effectively reduces the duration of endotracheal tube malposition in patients admitted to the intensive care unit (ICU). Additionally, the study will assess the clinical impact, usability, and user satisfaction of ETPAAS.\n\nThe main questions it aims to answer are:\n\n* Does ETPAAS reduce the duration of endotracheal tube malposition?\n* What are healthcare workers' perspectives on the usability and satisfaction of ETPAAS?\n\nParticipants will receive standard care, with or without ETPAAS, in the intensive care unit.\n\nResearchers will evaluate the duration of endotracheal tube malposition. Healthcare workers will complete a questionnaire assessing the usability and satisfaction of ETPAAS.",[28,91,92,93],"Mechanical Ventilation","Radiographic Image Interpretation, Computer-Assisted","Alarms",[95,96,97,98],"Chest X-ray","Chest radiograph","Endotracheal tube","Intubation, Intratracheal","NOT_YET_RECRUITING","2025-02-26",{"date":102,"type":36},"2025-03-04",{"date":104,"type":20},"2025-02-24",{"date":106,"type":20},"2025-12-31",{"name":108,"class":75},"Kaohsiung Medical University Chung-Ho Memorial Hospital",1]