[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"critical-care-nursing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:critical-care-nursing":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100607056","impact-of-infusion-line-change-frequency-on-infectious-complications-related-to-central-venous-catheters-in-the-icu---a-randomized-controlled-trial-100607056",false,"NCT07183592","Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial","Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the Intensive Care Unit ICU","TANDOORI","Inclusion criteria\n\n* Adult patient\n* Any ICU patient with a central venous catheter (inserted by venipuncture) in place for less than 72 hours and with an expected dwell time of at least 7 days\n* Patient affiliated with or covered by a social security system\n* Patient who has given verbal consent or written consent from a third party or in the event that the patient is unable to give consent.\n\nExclusion Criteria\n\n* Patient with a documented bloodstream infection at the time of inclusion\n* Patient whose central venous catheter has been in place for more than 72 hours\n* Patient with suspected catheter-related infection\n* Patient whose study catheter was inserted using a guidewire exchange\n* Patient previously enrolled in the study during the same ICU stay\n* Patient whose condition, according to the clinician, does not allow safe placement of a central venous catheter, such as:\n\n  * Allergy to catheter material\n  * Confirmed deep vein thrombosis at the time of insertion\n  * Inflammatory skin disorder at the insertion site\n* Patient admitted for extensive burns\n* Inadequate understanding of the French language\n* Pregnant, breastfeeding, or postpartum woman\n* Person deprived of liberty by judicial or administrative decision\n* Person receiving involuntary psychiatric care\n* Person under legal guardianship or other legal protection measure","ALL","18 Years",{"count":20,"type":21},2830,"ESTIMATED","INTERVENTIONAL",[24],"NA","In the intensive care unit, patients' care and secure drugs administration require a central venous catheter. These invasive devices can lead to complications, particularly infections. Most preventive recommendations focus on catheter insertion, line handling, and dressings. Few recommendations adress catheter dwell time, which is certainly the main source of infection. Part of the prevention strategy is the regular and systematic replacement of infusion sets , as they may become contaminated during use, mainly through the hands of healthcare professionals. Prolonged use increases the risk of infection. Infusion lines changes involve disconnecting the old sets, discarding infusion devices containing drug residues, and replacing them with new sterile devices.\n\nCurrent international guidelines recommend replacing these sets every 4 days, and the Center for Disease Control and Prevention recommends not exceeding 7 days. Replacing these devices requires the time of qualified nurses, numerous sterile medical devices, and medications. In addition to the intended effect on infection prevention, the procedure has impacts on workload and costs.\n\nThe objective of the study is to demonstrate that changing infusion set every 7 days does not increase the rate of central venous catheters related infections compared with changing infusion set every 4 days.",[27,28,29,30,31],"Intensive Care (ICU)","Central Venous Catheter Related Infections","Critical Care Nursing","Catheter-associated Bloodstream Infections (CLABSI)","Nursing Workload","RECRUITING","2026-05-12",{"date":35,"type":36},"2026-05-13","ACTUAL",{"date":33,"type":36},{"date":39,"type":21},"2028-12",{"name":41,"class":42},"University Hospital, Angers","OTHER_GOV",27,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":72},"100573210","speech-to-speech-voice-cloning-care-svcc-to-improve-icu-acquired-anxiety-for-critically-ill-patients-100573210","NCT06743321","Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients","A Prospective Study of the Effectiveness of Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients","Inclusion Criteria:\n\n* Expected mechanical ventilation time \\> 24 hours;\n* Expected ICU stay \\> 72 hours;\n* Language: Chinese;\n* Richmond Agitation-Sedation Scale (RAAS) score ≥ -2 points;\n* Hemodynamic stability.\n\nExclusion Criteria:\n\n* Severe hearing impairment or worse (Grade 3 or higher according to WHO's Grades of hearing impairment);\n* Disorders of consciousness or comprehension;\n* Mental or psychological disorders that are being treated with medication;\n* Head trauma or surgery resulting in an inability to wear earphones.",{"count":52,"type":21},234,[24],"The goal of this clinical trial is to learn the effect of Speech-to-speech Voice-Cloning Care (SVCC) on improving ICU-acquired anxiety for critically ill patients. The main question it aims to answer is:\n\n* Can the use of participants' loved ones' voices by nurses in communication while providing care lead to better mental health and clinical outcomes?\n\nResearchers will see if the implementation of SVCC can reduce anxiety and depression and improve clinical outcomes.\n\nParticipants will:\n\n* Receive the SVCC intervention until the endotracheal tube (ETT) is removed.\n* Keep a diary of delirium, the duration of mechanical ventilation, and ICU stays.",[29],[57,58,29,59,60],"ICU-acquired anxiety","Voice-cloning","Family-centered care","Artificial intelligence","NOT_YET_RECRUITING","2026-03-23",{"date":64,"type":36},"2026-03-25",{"date":66,"type":21},"2026-08-01",{"date":68,"type":21},"2027-12-31",{"name":70,"class":71},"Peking Union Medical College Hospital","OTHER",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":72},"100565453","the-effect-of-breathing-exercise-applied-to-intensive-care-nurses-on-fatigue-and-perceived-stress-100565453","NCT06642376","The Effect of Breathing Exercise Applied to Intensive Care Nurses on Fatigue and Perceived Stress","The Effect of Breathing Exercise Applied to Intensive Care Nurses on Fatigue and Perceived Stress: A Randomized Controlled Study","Inclusion Criteria:\n\n* Working in intensive care for at least 6 months\n* Volunteering to participate in the research\n* Not practicing any complementary therapies during the study, such as breathing exercises, acupuncture, massage therapy, relaxation techniques and yoga, which may be effective on perceived stress and fatigue\n\nExclusion Criteria:\n\n* Having a problem that prevents nasal breathing and prevents breathing exercises\n* Being pregnant\n* Experiencing physical and mental health problems that prevent communication",true,{"count":82,"type":21},60,[24],"The aim of this randomized controlled trial was to investigate the effect of breathing exercise on fatigue and stress in intensive care nurses.\n\nHypotheses of the study; H11: The level of perceived stress in nurses practicing breathing exercise is lower than the nurses in the control group.\n\nH12: The level of fatigue is lower in nurses practicing breathing exercise compared to nurses in the control group.\n\nData will be collected in the intervention and control groups with a pre-test data collection form before the intervention. Patients in the intervention group will be given breathing exercises, while patients in the control group will not receive any intervention. In the second week, interim follow-up data will be collected with the data collection form. At the end of the study; data will be collected from the intervention and control groups with post-test data collection forms.",[86,29],"Breathing Exercises",[88,89,90],"Stress","Nurse","Intensive care","2024-12-04",{"date":93,"type":36},"2024-12-05",{"date":95,"type":36},"2024-10-21",{"date":97,"type":21},"2025-01-15",{"name":99,"class":71},"Kahramanmaraş İstiklal University"]