[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"critically-ill-patients-admitted-to-the-icu-for-acute-respitatory-failure-regardless-the-aetilogy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:critically-ill-patients-admitted-to-the-icu-for-acute-respitatory-failure-regardless-the-aetilogy":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100568193","use-of-simplified-lung-ultrasound-score-for-predicting-icu-outcomes-in-patients-with-acute-respiratory-failure-100568193",false,"NCT06678035","Use of Simplified Lung Ultrasound Score for Predicting ICU Outcomes in Patients With Acute Respiratory Failure","Inclusion Criteria:\n\n* Age is or more than 18 years old.\n* Admission to ICU in the first24 hours at time of recruitment to the study.\n* Patients in respiratory failure \\[PaO2 is less then 60 % mmHg\\]\n\nExclusion Criteria:\n\n* Co- existing chronic lung disease, pathology of which is known display abnormalities on US examination (interstitial lung diseases, bronchiectasis).\n* Large pneumothorax or massive pleural effusion causing significant collapse and precluding proper visualization of underlying lung.\n* Conditions that may interfere with lung ultrasound quality or probe contact such as marked obesity, severe chest wall deformities, burns or wounds.","ALL","18 Days",{"count":18,"type":19},72,"ESTIMATED","OBSERVATIONAL","This study aims to\n\nPrimary Aims:\n\nVerify the predictability of the PLIS at admission in predicting major clinical outcomes including:\n\n* ICU mortality (or discharge) and time to death (or discharge)\n* Escalation of ventilatory support antibiotic therapy or supportive medications (inotropes, steroids, sedation, neuromuscular blockers).\n\nSecondary Aims:\n\n* Determine the correlation between initial PLIS and the degree of disease severity (as evaluated per SOFA and APACHE II scores)\n* Determine the correlation between initial PLIS and partial pressure of oxygen in arterial blood (PaO2) to Fraction of inspired oxygen (FiO2): PaO2\u002FFiO2\n* Explore the potential association between the type of ventilatory support, ventilatory settings and PLIS at different time points.\n* Verify whether the site of consolidation (anterior vs. posterior lung zones) can reliably predict mortality in in ALI patients.\n* Determine the correlation between the PLIS score and the degree of ALI as quantified by CT of the chest (whenever a CT study is available) at the time of admission.",[23,24,25],"Pneumnia","Chest Infection","Critically-ill Patients Admitted to the ICU for Acute Respitatory Failure, Regardless the Aetilogy",[27,28,29],"LUS","Acute respiratory failure","Critically-ill patients","NOT_YET_RECRUITING","2024-11-05",{"date":33,"type":34},"2024-11-07","ACTUAL",{"date":36,"type":19},"2024-11-20",{"date":38,"type":19},"2025-10-01",{"name":40,"class":41},"Assiut University","OTHER"]