[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"crowding-tooth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:crowding-tooth":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100608716","gingival-phenotype-and-dental-crowding-in-pediatric-patients-100608716",false,"NCT07205172","Gingival Phenotype and Dental Crowding in Pediatric Patients","Gingival Phenotype and Dental Crowding in Pediatric Patients, a Pilot Study","BIOTIPO_PEDO","Inclusion Criteria:\n\n* Pediatric patients attending the Pediatric Dentistry and\u002For Orthodontics clinic (consultation and\u002For outpatient appointment).\n* Parents and\u002For legal guardians have signed the informed consent for participation in the study.\n* Age between 5 and 16 years.\n* Clinical dentition criteria by group:\n\nGroup 1 (Primary Dentition): Presence in the mandibular arch of deciduous teeth from canine to canine. Group 2 (Early Mixed Dentition): Presence in the mandibular arch of at least two permanent mandibular incisors, fully erupted (incisal edge at occlusal level) or partially erupted (≥50% of the crown), with no clinical attachment loss, and healthy gingiva or mild gingivitis (Gingival Index, GI ≤ 1). Group 3 (Late Mixed Dentition): Presence in the mandibular arch of all four permanent mandibular incisors fully erupted (incisal edge at occlusal level), with no clinical attachment loss, and healthy gingiva or mild gingivitis (GI ≤\n\n1). Group 4 (Permanent Dentition): Presence in the mandibular arch of all four permanent mandibular incisors fully erupted (incisal edge at occlusal level), with no clinical attachment loss, and healthy gingiva or mild gingivitis (GI ≤ 1).\n\nExclusion Criteria:\n\nPatient-related:\n\n* Parents and\u002For legal guardians have not signed the informed consent.\n* Patients who are not sufficiently cooperative to allow a routine dental examination.\n* Non-cooperative patients, including those with special needs.\n* Children with systemic diseases or undergoing medication that affects gingival tissues.\n* Patients who have already undergone orthodontic treatment or are currently undergoing orthodontic treatment.\n\nTooth-related:\n\n* Presence of dental agenesis or dental anomalies.\n* Dental sites with mucogingival problems.",true,"ALL","5 Years","16 Years",{"count":22,"type":23},180,"ESTIMATED","OBSERVATIONAL","The periodontal phenotype influences treatment outcomes across dental specialties, as tissues of different thickness respond differently to chemical, bacterial, and mechanical insults. In pediatric patients, understanding the gingival phenotype is particularly relevant: a thin phenotype may predispose to dehiscence, fenestration, and gingival recession-especially at the mandibular incisors-when tooth movement exceeds the biological limits of the bony housing.\n\nDuring the mixed dentition phase, significant changes in soft and hard tissues affect tooth position and periodontal stability, making early phenotype assessment essential. Interceptive orthodontics can reduce the long-term risk of mucogingival defects; early identification of a thin biotype allows for preventive strategies, including soft tissue grafting before critical orthodontic movements.\n\nNo studies have examined the association between dental crowding severity and periodontal phenotype in children. Adult data remain inconsistent: Kaya et al. found no correlation between phenotype and skeletal malocclusion, while Kong et al. reported a site-specific association between thin biotype and skeletal Class I\u002FIII at the mandibular central incisor. No predictive model exists for periodontal risk related to severe crowding in childhood.\n\nThis study aims to assess the periodontal phenotype in pediatric patients across different stages of dental transition and to investigate a possible association between a thin periodontal biotype and severe dental crowding.",[27,28],"Crowding, Tooth","Gingival Diseases","RECRUITING","2026-05-21",{"date":32,"type":33},"2026-05-26","ACTUAL",{"date":35,"type":33},"2025-12-16",{"date":37,"type":23},"2027-04",{"name":39,"class":40},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":41},"100555753","efficacy-and-effectiveness-of-two-types-of-aligners-based-on-stratification-by-type-of-movement-100555753","NCT06516185","Efficacy and Effectiveness of Two Types of Aligners Based on Stratification by Type of Movement","Randomized Clinical Trial on the Efficacy and Effectiveness of Two Types of Aligners Based on Stratification by Type of Movement.","Inclusion Criteria:\n\n* Patients with malocclusion and invididual dental malpositions requiring orthodontic treatment\n* Adequate oral and periodontal health, with absence of periodontal disease, periapical infection or untreated caries.\n* No history of previous orthodontic treatment.\n* Complete permanent dentition (excluding third molars, their presence or absence being irrelevant).\n\nExclusion Criteria:\n\n* Altered bone metabolism (including use of antiresorptive, steroid or immunosuppressive drugs).\n* Pregnant women.",{"count":50,"type":23},114,"INTERVENTIONAL",[53],"NA","The purpose of this study is to evaluate the biomechanical behaviour of direct-printed and thermoformed aligners in different tooth movements, creating a biomechanical planning protocol based on a stratification of tooth movements according to the degree of predictability.",[27,56,57,58],"Tipped Tooth or Teeth","Rotation of Tooth","Malocclusion, Angle's Class",[60,61,62,63,64],"clear aligner therapy","direct-printed aligner","predictability","shape memory","stratification","2024-12-11",{"date":67,"type":33},"2024-12-12",{"date":69,"type":33},"2024-10-22",{"date":71,"type":23},"2026-06",{"name":73,"class":40},"Universidad Complutense de Madrid"]