[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cruciate-ligament-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cruciate-ligament-injury":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100631870","biological-potentials-in-arthroscopic-all-inside-semitendinosus-anterior-cruciate-ligament-reconstruction-100631870",false,"NCT07506304","Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction","A Double-blind, Randomized, Prospective, Single-center Study of Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction","BioACL","Inclusion Criteria:\n\n* Clinically and radiologically confirmed anterior cruciate ligament (ACL) rupture.\n* Age between 18 and 50 years.\n* Intact posterior cruciate ligament and collateral ligaments.\n* Signed informed consent to participate in the study.\n* Patients meeting at least one indication for concomitant lateral tenodesis, including: age under 25 years, positive pivot-shift test, presence of Segond fracture, participation in sports with frequent changes of direction and rotational knee loads, or joint hypermobility (Beighton score ≥ 7).\n\nExclusion Criteria:\n\n* Previous ACL reconstruction of the same knee.\n* Inability to use a graft prepared by quadruple folding of the semitendinosus tendon.\n* Graft diameter \\\u003C 7.5 mm.\n* MRI-confirmed unsuccessful meniscal healing after repair.\n* Acute joint infection or history of joint infection.","ALL","18 Years","50 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","A randomized, double-blind, prospective single-center clinical trial evaluating the effect of biological augmentation in anterior cruciate ligament (ACL) reconstruction. The study compares standard all-inside semitendinosus ACL reconstruction versus biologically enhanced reconstruction incorporating muscle tissue preservation and autologous bone and fibrin augmentation. The primary aim is to assess whether biological augmentation improves graft healing, integration, and clinical outcomes.",[28,29,30],"Cruciate Ligament Reconstruction","Cruciate Ligament Rupture","Cruciate Ligament Injury",[32,33,34,35,36],"Tissue Remodeling","Anterior Cruciate Ligament","Semitendinosus Muscle","Knee","Arthroscopy","NOT_YET_RECRUITING","2026-04-13",{"date":40,"type":41},"2026-04-16","ACTUAL",{"date":43,"type":22},"2026-09-01",{"date":45,"type":22},"2032-12-31",{"name":47,"class":48},"University Hospital Dubrava","OTHER"]