[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cruciate-ligament-reconstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cruciate-ligament-reconstruction":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100631870","biological-potentials-in-arthroscopic-all-inside-semitendinosus-anterior-cruciate-ligament-reconstruction-100631870",false,"NCT07506304","Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction","A Double-blind, Randomized, Prospective, Single-center Study of Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction","BioACL","Inclusion Criteria:\n\n* Clinically and radiologically confirmed anterior cruciate ligament (ACL) rupture.\n* Age between 18 and 50 years.\n* Intact posterior cruciate ligament and collateral ligaments.\n* Signed informed consent to participate in the study.\n* Patients meeting at least one indication for concomitant lateral tenodesis, including: age under 25 years, positive pivot-shift test, presence of Segond fracture, participation in sports with frequent changes of direction and rotational knee loads, or joint hypermobility (Beighton score ≥ 7).\n\nExclusion Criteria:\n\n* Previous ACL reconstruction of the same knee.\n* Inability to use a graft prepared by quadruple folding of the semitendinosus tendon.\n* Graft diameter \\\u003C 7.5 mm.\n* MRI-confirmed unsuccessful meniscal healing after repair.\n* Acute joint infection or history of joint infection.","ALL","18 Years","50 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","A randomized, double-blind, prospective single-center clinical trial evaluating the effect of biological augmentation in anterior cruciate ligament (ACL) reconstruction. The study compares standard all-inside semitendinosus ACL reconstruction versus biologically enhanced reconstruction incorporating muscle tissue preservation and autologous bone and fibrin augmentation. The primary aim is to assess whether biological augmentation improves graft healing, integration, and clinical outcomes.",[28,29,30],"Cruciate Ligament Reconstruction","Cruciate Ligament Rupture","Cruciate Ligament Injury",[32,33,34,35,36],"Tissue Remodeling","Anterior Cruciate Ligament","Semitendinosus Muscle","Knee","Arthroscopy","NOT_YET_RECRUITING","2026-04-13",{"date":40,"type":41},"2026-04-16","ACTUAL",{"date":43,"type":22},"2026-09-01",{"date":45,"type":22},"2032-12-31",{"name":47,"class":48},"University Hospital Dubrava","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100624008","comparison-of-tendon-and-muscle-tendon-semitendinosus-grafts-after-acl-reconstruction-100624008","NCT07404046","Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction","Comparison of Bone Ingrowth and Intra-articular Remodeling of Autologous Tendon and Muscle-tendon Semitendinosus Graft After Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery","CandyStripe",{"count":57,"type":22},40,[25],"Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft. Subjects and methods: It is a single-blind prospective randomized study that would include at least 40 patients with an anterior cruciate ligament rupture. Patients would be randomly divided into two groups of minimally 20 patients each. Patients in the first study group would undergo ACL reconstruction with a muscle-tendon graft, while patients in the control group would be treated with the standard method of ACL reconstruction with a tendon graft.\n\nExpected contribution to the field: The assumption is that the obtained results could enable a better understanding of the contribution of remaining muscle fibers on the tendon in anterior cruciate ligament reconstruction operations to the tendon to bone ingrowth and intra-articular remodeling of the graft of operated patients.",[28],[36,32,33,34,35],"RECRUITING","2026-02-07",{"date":65,"type":41},"2026-02-11",{"date":67,"type":22},"2026-02",{"date":69,"type":22},"2027-09",{"name":47,"class":48},1]