[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"curative-treatment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:curative-treatment":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,60],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100597416","weight-management-in-obese-cancer-patients-during-curative-active-treatment-100597416",false,"NCT07058207","Weight Management in Obese Cancer Patients During Curative Active Treatment","Weight Management in Obese Cancer Patients During Curative Active Treatment (CANOBESE Study): A Feasibility Study","CANOBESE","Inclusion Criteria:\n\n* Adult (age 18+) with pathologically confirmed malignant solid tumors, stage II-IV, elected for oncological treatment (chemo, radio, or both) with curative intend.\n* Expected oncological treatment time ≥ 3 months.\n* BMI ≥ 30 kg\u002Fm²\n* Resident in the Barcelona area up to the completion of cancer treatment.\n* ECOG Perfomance Status (PS) 0-1\n* Availability of internet access.\n\nExclusion Criteria:\n\n* Patients with melanoma and brain tumours.\n* Surgery as the only treatment.\n* Tumour localizations with high risk of malnutrition (such as head and neck, upper gastrointestinal tract, or pancreatic cancer):\n* Pregnancy or breastfeeding\n* Another active malignancy\n* Current health or medical condition that affects weight status, e.g., untreated hyper- or hypothyroidism,etc\n* Pre-existing medical condition that precludes adherence to unsupervised exercise, e.g., severe orthopedic conditions, scheduled for a hip or knee replacement, bone metastases, paralysis, dementia, untreated stage 3 hypertension, or unstable angina, heart attack, congestive heart failure or conditions that dictated hospitalization or oxygen within 6-months.\n* Unable to read or understand Spanish or Catalan\n* Enrolled in a weight loss program\n* Active suicidal ideation, anorexia, bulimia, binge eating disorder, current substance abuse or dependence (besides nicotine dependence)\n* Use of pacemaker or another electrical implanted device\n* History of bariatric (or LapBand) surgery, or considering or currently on a wait-list for bariatric or LapBand surgery\n* Patients with any concurrent medical or psychological condition that, in the investigator's opinion, would jeopardize the safety of the patient or compliance with the protocol.","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a feasibility study intervention to fifty cancer patients with obesity and with newly diagnosed stage II-IV solid tumors undergoing curative treatment recruited at the Catalan Institute of Oncology (ICO) in L'Hospitalet, Spain.\n\nThe investigators hypothesize that weight management during cancer treatment could enhance health outcomes for this population. The feasibility of a multimodal weight loss management program will be assesses, including a personalized hypocaloric and high-protein diet combined with a supervised exercise home-program and behavioural support.",[27,28,29,30],"Obesity","Solid Neoplasm","Stage II-IV","Curative Treatment",[27,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46],"Neoplasms","Antineoplasic agents","Chemotherapy","Radiotherapy","Weight Loss","Physical Activity","Feasibility Studies","Patient Compliance","Patient Motivation","Patient Adherence","Patient Dropouts","Treatment-related adverse effects","Biomarkers","nutritional intervention","curative-intent treatment","RECRUITING","2025-07-24",{"date":50,"type":51},"2025-07-28","ACTUAL",{"date":53,"type":51},"2025-07-22",{"date":55,"type":21},"2027-03",{"name":57,"class":58},"Institut d'Investigació Biomèdica de Bellvitge","OTHER",1,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":68,"minAge":18,"maxAge":4,"enrollmentInfo":69,"targetDuration":4,"studyType":22,"phases":71,"briefSummary":72,"conditions":73,"keywords":81,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":59},"100533802","adaptive-radiotherapy-in-patients-with-gynecological-tumors-100533802","NCT06230549","Adaptive Radiotherapy in Patients With Gynecological Tumors","Prospective Randomized Validation of Adaptive Radiotherapy in Patients With Gynecological Tumors and Indication for Radiotherapy","ProART","Inclusion Criteria:\n\nECOG 0-1 confirmation by histophatology MR of the pelvis staging\n\nExclusion Criteria:\n\nRecurrent disease Prior Radiotherapy in pelvic region stage pM1 or cM1","FEMALE",{"count":70,"type":21},30,[24],"Prospective randomized evaluation of adaptive radiotherapy in the definitive radiotherapy of locally advanced gynecologic carcinoma (e.g. cervical carcinoma, endometrial carcinoma, vaginal carcinoma), in the postoperative situation or first series of external beam radiotherapy and in patients in whom radical surgery or HDR brachytherapy as dose boost is not an option.",[74,75,76,30,77,78,79,80],"Gynecological Tumor","Adaptive Radiotherapy","Radiation","Optimization","Adaptive Radiation Therapy","Image Guided Radiotherapy","Cervical Carcinoma",[82,83,84,85,86,87,88,89],"gynecological tumor","adaptive radiotherapy","radiation","curative treatment","optimization","adaptive radiation therapy","image guided radiotherapy","Cervical carcinoma","2024-02-07",{"date":92,"type":51},"2024-02-09",{"date":94,"type":51},"2024-01-15",{"date":96,"type":21},"2026-12-15",{"name":98,"class":58},"University Hospital, Essen"]