[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cystic-fibrosis-with-intestinal-manifestations\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cystic-fibrosis-with-intestinal-manifestations":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100494843","the-effects-of-a-low-glycemic-load-diet-on-dysglycemia-and-body-composition-in-adults-with-cystic-fibrosis-related-diabetes-100494843",false,"NCT05723445","The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes","DINE","Inclusion Criteria:\n\n* 18 years and above\n* Genetically confirmed diagnosis of CF\n* Diagnosis of pancreatic insufficiency, requiring pancreatic enzyme replacement\n* Criteria for CFRD:\n\nA.) Most recent OGTT 2-hour glucose \\>200 mg\u002FdL within the past two years, and\u002For; B.) HbA1c \\>6.5% in the past two years, and\u002For; C.) Current use of insulin\n\nExclusion Criteria:\n\n* FEV1 \\\u003C50% predicted on most recent pulmonary function testing\n* BMI \\\u003C18 kg\u002Fm2\n* Currently receiving enteral nutrition support via GT feeds\n* Pregnancy, plan to become pregnant in the next 3-months, or sexually active without use of contraception\n* Use of IV antibiotics or systemic supraphysiologic glucocorticoids for CF exacerbation within 1 month\n* Started or stopped treatment with a CFTR modulator within 3 months of enrollment\n* Currently adhering to an LGL or other carbohydrate-restricted diet (carbohydrate intake \\\u003C30% of total daily caloric intake)","ALL","18 Years","70 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults with cystic fibrosis-related diabetes (CFRD). We will use continuous glucose monitors (CGM) to assess the LGL diet both in a controlled setting (via a meal delivery company) and in free-living conditions.",[27,28,29],"Cystic Fibrosis","Cystic Fibrosis-related Diabetes","Cystic Fibrosis With Intestinal Manifestations",[31,32,33,34],"Cystic Fibrosis-Related Diabetes","Low Glycemic Load","Continuous Glucose Monitoring","Body Composition","RECRUITING","2025-08-16",{"date":38,"type":39},"2025-08-22","ACTUAL",{"date":41,"type":39},"2023-09-01",{"date":43,"type":21},"2026-07-01",{"name":45,"class":46},"Rhode Island Hospital","OTHER",2]