[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"day-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:day-surgery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100565056","clinical-research-on-the-treatment-model-of-ambulatory-surgery-for-colorectal-cancer-100565056",false,"NCT06637215","Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer","Open, Parallel, Randomized Controlled, Non-inferior, Phase III Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer","Inclusion Criteria:\n\n1. Patients voluntarily joined this study and signed an informed consent form；\n2. Age: 18-75 years old；\n3. The patient should have a good general condition and no serious internal medicine comorbidities (ASA classification of the American Anesthesiology Association is Grade I\\~III)；\n4. Complete colonoscopy and colonoscopy biopsy, and the pathology is confirmed to be adenocarcinoma\u002Fhigh-level intraepithelial neoplasia；\n5. Enhanced CT or MRI examination before surgery, indicating that the tumor diameter is ≤5.0 cm；\n6. Preoperative staging: cT1-3NanyM0;\n7. Strictly follow the colorectal day surgery plan, and micro-laparoscopic radical colorectal cancer treatment can be adopted；\n8. There are no contraindications for abdominal wall nerve block anesthesia or non-opiate analgesic drugs;\n9. Does not require conventional anticoagulant therapy or antiplatelet therapy；\n10. Relatives or co-residents should be able to provide 24 hours of full escort within at least 72 hours after the operation, the place of residence is not more than a 30-minute drive from the hospital, and they can understand and follow the phased treatment plan of diet, analgesic drugs, etc. after the operation.\n\nExclusion Criteria:\n\n1. Elderly patients with multiple basic diseases；\n2. Moderate to severe anemia；\n3. Severe hypoproteinemia；\n4. Diabetes that is not well controlled；\n5. Contraindications to laparoscopic surgery；\n6. Cases of emergency surgery due to acute intestinal obstruction, perforation or bleeding；\n7. Patients with distant metastases；\n8. Patients who are unwilling to sign informed consent or follow-up according to the research plan；\n9. People with a history of psychotropic drug abuse and unable to quit or have mental disorders；\n10. Patients who live alone or in psychosocial isolation, patients who cannot understand the postoperative nursing process；\n11. After the operation, the place of residence is far away from the treated hospital or patients with insufficient medical resources and inconvenient transportation；\n12. According to the judgment of the researcher, there are concomitant diseases that seriously endanger the safety of the patient or affect the completion of the patient\\'s research.","ALL","18 Years","75 Years",{"count":20,"type":21},352,"ESTIMATED","INTERVENTIONAL",[24],"NA","To investigate the postoperative complication incidence and long-term efficacy between ambulatory surgery for colorectal cancer and traditional laparoscopic colorectal surgery in patients with colorectal tumor who are generally in good health and have sufficient organ functions。",[27,28],"Colorectal Carcinoma","Day Surgery",[30,31,32],"Colorectal cancer","Day surgery","Laparoscope","RECRUITING","2024-11-24",{"date":36,"type":37},"2024-11-27","ACTUAL",{"date":39,"type":37},"2023-11-01",{"date":41,"type":21},"2029-03-31",{"name":43,"class":44},"First Hospital of China Medical University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":45},"100559622","thoracic-paravertebral-block-in-daytime-laparoscopic-partial-adrenalectomy-100559622","NCT06566521","Thoracic Paravertebral Block in Daytime Laparoscopic Partial Adrenalectomy","Effect of Thoracic Paravertebral Block on Analgesia and the Quality of Recovery Following Daytime Laparoscopic Partial Adrenalectomy","Inclusion Criteria:\n\n* Aged 18 to70 years\n* Body Mass Index (BMI) 18.5 to 30 kg\u002Fm²\n* American Society of Anesthesiologists (ASA) grade I to II classification\n* unilateral non-functional adrenal adenoma with a tumor diameter greater than 20mm\n\nExclusion Criteria:\n\n* Patients with peripheral nervous system disease\n* Patients with spinal deformity or surgery\n* Patients with puncture site infection or coagulation abnormalities\n* Patients with history of postoperative nausea and vomiting or allergy to local anesthetics\n* Patients with unstable mental illness or refusal to participate","70 Years",{"count":55,"type":21},80,[24],"Day surgery refers to the entire diagnostic and therapeutic process completed within 24-48 h, including patient admission, surgery, and discharge. Research by Shariq et al suggested that daytime laparoscopic adrenalectomy was a safe and effective alternative to traditional inpatient treatment. Li et al demonstrated that daytime surgery for laparoscopic partial adrenalectomy could reduce hospital stays, lower medical costs, and optimize healthcare resource utilization.\n\nThe day surgery has put forward higher requirements for the management of perioperative anesthesia, in which the postoperative multimodal analgesia is particularly important.Thoracic paravertebral block (TPVB) is a regional block technique in which local anaesthetics can be injected into paravertebral space to block the ipsilateral sympathetic and somatosensory nerves. TPVB single point injection can achieve sensory block of 3-6 spinal ganglia on one side, with minimal impact on respiratory, gastrointestinal and bladder function. Especially, TPVB does not affect motor nerve, which enable patients to perform painless functional exercise shortly after surgery, promote rapid recovery, and enhance satisfaction and comfort.\n\nA large number of previous studies have shown that TPVB had become increasingly popular for postoperative analgesia after thoracic or breast surgery. However, to our knowledge, few studies to date have investigated the application of TPVB in daytime adrenal surgery. Therefore, we conducted this randomized clinical trial to examine the effect of TPVB on postoperative analgesia and the quality of recovery in patients following daytime laparoscopic partial adrenalectomy.",[59,28],"Laparoscopic Adrenalectomy",[61,62,63,64,65],"laparoscopic partial adrenalectomy","thoracic paravertebral block","daytime mode","analgesia","recovery quality","2024-10-28",{"date":68,"type":37},"2024-10-31",{"date":70,"type":37},"2024-08-23",{"date":72,"type":21},"2024-11-15",{"name":74,"class":44},"Shanxi Bethune Hospital"]