[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"death-anxiety\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:death-anxiety":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,49,97,127,153,175,199],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100633346","die-logue-program-for-community-dwelling-adults-a-randomized-controlled-trial-100633346",false,"NCT07525492","Die-logue Program for Community Dwelling Adults: A Randomized Controlled Trial","Effects of a Die-logue Program in Enhancing Community Dwelling Adults's Death Attitudes, Coping With Death and Readiness for Advance Care Planning: A Two-phase Study","Inclusion Criteria:\n\n* Between the ages of 40 to 60 years\n* Able to comprehend the English language\n* Have not completed any form of advance directives\n* Able and willing to participate in the Die-logue programme and surveys\n\nExclusion Criteria:\n\n* Individuals diagnosed with any life limiting diseases\n* Individuals with self-reported history of mental health disorders or neurological disorders",true,"ALL","40 Years","60 Years",{"count":21,"type":22},148,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to evaluate whether the Die-logue program can improve attitudes toward death, coping with death, and readiness for advance care planning (ACP) among community-dwelling middle-aged adults aged 40-60 years who have not completed any advance directives and not diagnosed with any life limiting diseases.\n\nThis study aims to address the following research questions:\n\n* Does the Die-logue program improve community-dwelling middle-aged adults' attitudes towards death, ability to cope with death, readiness and uptake for Advanced Care Planning (ACP).\n* What are community-dwelling middle-aged adults' perceptions of advance care planning, death and dying, and their experiences of participation in the Die-logue program.\n\nResearchers will compare participants who receive the Die-logue program (death conversation and online ACP education) with participants who receive only the online ACP education to see if informal death conversations improve attitudes toward death, coping with death, and readiness for ACP.\n\nParticipants will:\n\n* Complete online questionnaires measuring attitudes toward death, coping with death, and readiness for advance care planning.\n* Participate in a facilitator-led group discussion session about perceptions of death, coping with death, and readiness for ACP (intervention group only).\n* Complete an asynchronous online ACP education session consisting of short recorded videos and an online discussion forum (both intervention and control group).\n* Complete follow-up surveys, including a 6-month follow-up assessing whether they have undertaken advance care planning.",[28,29,30,31],"Death Attitude (Implicit\u002FExplicit)","Death Anxiety","End of Life Care","Advanced Care Planning (ACP)",[33,29,34,35],"Death Conversation","Advance Care Planning","Death Attitude","NOT_YET_RECRUITING","2026-04-06",{"date":39,"type":40},"2026-04-13","ACTUAL",{"date":42,"type":22},"2026-04-01",{"date":44,"type":22},"2027-12-31",{"name":46,"class":47},"National University of Singapore","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":76,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":4},"100629619","non-invasive-detection-and-preservation-of-neurocognitive-signals-in-the-peri-death-period-using-brain-computer-interface-and-artificial-intelligence-100629619","NCT07477028","Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence","Feasibility of Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence: A Prospective Observational Study (NeuroCogPresv)","NeuroCogPresv","Inclusion Criteria:\n\n1. Adults ≥18 years with terminal illness or severe acute trauma\n2. Do-not-resuscitate (DNR\u002FDNI) order in place\n3. Surrogate decision-maker available and willing to provide informed consent\n4. Expected survival ≤7 days (physician estimate)\n\nExclusion Criteria:\n\n1. Brain death already declared \\> 24 hours prior to enrollment\n2. Contraindication to EEG\u002FBCI headset placement (e.g., severe scalp injury)\n3. Patient lacks a legally authorized representative","18 Years",{"count":59,"type":22},20,"OBSERVATIONAL","Background: Recent electroencephalography (EEG) data indicate that the transition from clinical death to cellular death is marked by highly organized neurophysiological events, including significant surges in gamma-band power, cross-frequency coupling, and distinct spreading depolarization waves. This prospective, observational feasibility study utilizes rapid-deployment, high-density, noninvasive BCI hardware paired with proprietary AI analytics to detect, classify, and securely archive these terminal neurocognitive signals.\n\nObjectives: (1) Quantify transient gamma-band activity and cross-frequency connectivity post-clinical death; (2) Validate the efficacy of machine learning models for real-time signal classification in high-noise clinical environments; (3) Establish a highly secure, encrypted bio-informational archive of peri-life EEG data.\n\nDesign: Prospective, open-label, multicenter, observational cohort (n\\>20).",[63,64,65,66,29,67,68,69,70,71,72,73,74,75],"Terminal Illness","End-of-Life Care","Death","Brain Death","Consciousness","Electroencephalography","Gamma Oscillations","Near-Death Phenomena","Cognitive","Cognition","Memory","EEG","Severe Acute Trauma",[77,78,79,65,69,72,67,80,81,82,73,83,84,85,86],"AI","BCI","Brain Computer Interface","Pefi-death","Brain death","Reservation","Life","Life experience","Transfer","Convergence","2026-03-12",{"date":89,"type":40},"2026-03-17",{"date":91,"type":22},"2026-09-01",{"date":93,"type":22},"2035-09-30",{"name":95,"class":96},"Noah Tech, Corp.","INDUSTRY",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":23,"phases":107,"briefSummary":108,"conditions":109,"keywords":112,"overallStatus":117,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":48},"100608432","death-anxiety-depression-and-anxiety-an-experimental-study-100608432","NCT07201480","Death Anxiety, Depression and Anxiety: An Experimental Study","Death Anxiety: Implications for Depression and Anxiety - An Experimental Study","Inclusion Criteria:\n\n* Age over 18 years.\n* Living in Cluj-Napoca (or otherwise willing and able to participate in the lab task)\n\nExclusion Criteria:\n\n* Personality disorder diagnosis\n* Psychotic disorder diagnosis\n* Suicidal ideation","65 Years",{"count":106,"type":22},128,[25],"The goal of this experimental study is to investigate the transdiagnostic role of death anxiety in depression and anxiety symptoms in participants from the general population.\n\nThe main questions it aims to answer are:\n\n1. Does the mortality salience task induce death anxiety?\n2. Does the experimental group present an increase in depression and anxiety symptoms following the mortality salience task?\n\nThe investigators will compare the experimental condition to a control condition to see if the death anxiety induction is responsible for the expected increase in depression and anxiety symptoms.\n\nThe mortality salience prompt will be asking participants to elaborate on their thoughts and feelings surrounding death and dying, including what they think happens during death. The dental pain prompt will ask participants to do the same, only in regards to the thought of having dental pain.\n\nExperimental group: participants will undergo a pen-and-paper writing task where they will be asked to answer two questions:\n\n1. \"Please briefly describe the emotions that the thought of your own death arouses in you.\"\n2. \"Jot down, as specifically as you can, what you think will happen to you physically as you die and once you are physically dead.\"\n\nControl group:\n\n1. \"Please briefly describe the emotions that the thought of dental pain arouses in you.\"\n2. \"Jot down, as specifically as you can, what you think happens to you physically as you experience dental pain and once you have physically experienced dental pain.\"",[29,110,111],"Depression","Anxiety",[113,114,115,116],"death anxiety","depression","anxiety","transdiagnostic","RECRUITING","2025-09-23",{"date":120,"type":40},"2025-10-01",{"date":122,"type":40},"2025-03-01",{"date":124,"type":22},"2026-01",{"name":126,"class":47},"Babes-Bolyai University",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":104,"enrollmentInfo":135,"targetDuration":4,"studyType":23,"phases":137,"briefSummary":138,"conditions":139,"keywords":140,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":48},"100583421","effectiveness-of-an-online-religiously-integrated-cognitive-behavioral-therapy-based-intervention-on-death-anxiety-100583421","NCT06876103","Effectiveness of an Online Religiously-integrated Cognitive Behavioral Therapy-based Intervention on Death Anxiety","Investigating the Effectiveness of an Online Religiously-integrated Cognitive Behavioral Therapy-based Intervention on Death Anxiety","RCBT-DA","Inclusion Criteria:\n\n* Aged 18-65\n* A score of \\> 26 on the Turkish Death Anxiety Scale\n* Diagnosed with one of the anxiety disorders\n* Believing in life after death\n\nExclusion Criteria:\n\n* Diagnosed with schizophrenia, schizophreniform disorder, schizoaffective disorder, and delusional disorder\n* Being in an active manic episode\n* Possessing a mental disorder that interferes with completing measures or understanding the exercises conducted during sessions\n* Extreme symptoms of depression (score of \\> 20 on the Patient Health Questionnaire (PHQ-9), and \\>1 on the item assessing suicidality)\n* Currently receiving therapy.",{"count":136,"type":22},44,[25],"There has been growing awareness of the importance of death anxiety (DA) in pathological anxiety. DA is defined as a persistent and unreasonable fear of death and thoughts, fears, and emotions associated with the end of life. DA has been suggested as a core fear that underpins the emergence and perseverance of numerous anxiety disorders. However, previous DA-based treatment studies focus on the elderly, the patients, or health professionals who care for the terminally ill. Therefore, there is a need to examine the effect of psychological interventions on DA and current disorder symptoms in a clinical sample through randomized controlled trials. The current study aims to develop a novel Religiously Integrated Cognitive Behavioral Therapy (RCBT)-based intervention on DA in individuals diagnosed with an anxiety disorder and to compare the effectiveness of RCBT-based intervention with classical CBT-based intervention.",[29],[113,141,142,143],"religiously integrated cognitive behavioral therapy","classical cognitive behavioral therapy","randomized control study","2025-05-28",{"date":146,"type":40},"2025-06-03",{"date":148,"type":22},"2025-06-01",{"date":150,"type":22},"2025-12-01",{"name":152,"class":47},"Ibn Haldun University",{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":16,"sex":17,"minAge":161,"maxAge":4,"enrollmentInfo":162,"targetDuration":4,"studyType":23,"phases":164,"briefSummary":165,"conditions":166,"keywords":4,"overallStatus":117,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":48},"100592299","the-effect-of-situation-puzzle-games-on-nursing-students-death-anxiety-and-meaning-in-life-100592299","NCT06991621","The Effect of Situation Puzzle Games on Nursing Students' Death Anxiety and Meaning in Life","Mechanisms and Design Framework Study of Gamified Education in Professional Identity Formation for Medical Undergraduates","SPGI","Inclusion Criteria:\n\n* Third-year full-time undergraduate nursing students\n* Completed clinical observation training but not yet entered clinical internship phase\n* Aged ≥18 years\n* Provide informed consent and voluntarily participate in the study\n\nExclusion Criteria:\n\n* Participated in similar death education interventions within the past 3 months\n* Diagnosed with severe mental or psychological disorders\n* Currently on a leave of absence (academic or personal)","18 Months",{"count":163,"type":22},70,[25],"Goal of this interventional study\n\nThe purpose of this research is to investigate the effects of a scenario-based puzzle educational game on death anxiety and meaning in life among nursing students. It aims to answer the following key questions:\n\nCan the scenario-based puzzle educational game enhance nursing students' sense of meaning in life?\n\nCan the scenario-based puzzle educational game reduce death anxiety in nursing students?\n\nWhat are nursing students' experiences and perceptions of this educational game?\n\nStudy design Researchers will compare the intervention group (participating in the game) with a control group (receiving death education manuals) to evaluate the effectiveness of the game-based intervention.\n\nParticipants will:\n\nBe recruited through campus posters\n\nBe randomly assigned to either the intervention or control group and complete baseline questionnaires\n\nIn the control group: Receive death education manuals twice weekly for 3 weeks\n\nIn the intervention group: Participate in group sessions (5 students per group) to play the scenario-based puzzle game twice weekly for 3 weeks\n\nComplete follow-up questionnaires and participate in qualitative interviews regarding their experiences with manual-based education or the game intervention after the 3-week intervention period",[29],"2025-05-18",{"date":144,"type":40},{"date":170,"type":40},"2025-04-21",{"date":172,"type":22},"2025-08-21",{"name":174,"class":47},"China Medical University, China",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":23,"phases":183,"briefSummary":184,"conditions":185,"keywords":187,"overallStatus":117,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":48},"100589659","the-effect-of-mindfulness-based-death-psychoeducation-program-on-death-awareness-and-death-anxiety-levels-in-nurses-100589659","NCT06957288","The Effect of Mindfulness-Based Death Psychoeducation Program on Death Awareness and Death Anxiety Levels in Nurses","Inclusion Criteria:\n\n* Working as a nurse in Palliative Care services, emergency services and intensive care units\n\nExclusion Criteria:\n\n* Working as a nurse outside of Palliative Care services, emergency services and intensive care units",{"count":182,"type":22},30,[25],"Nurses are the primary caregivers for individuals who experience difficult situations (disease, loss, etc.) or are in the terminal phase. This may cause nurses to be exposed to the same experiences secondarily. Coming face to face with death can be a traumatic experience for individuals. Whether death is a traumatic experience for nurses may vary depending on individual differences and environmental conditions. Factors affecting nurses in this sense include the unit they work in, death anxiety, death awareness, workload, and sociodemographic characteristics. Studies conducted with nurses indicate that nurses' death anxiety varies depending on the unit and other factors, and that nurses need training for death awareness and the right approach to individuals. A study conducted on death education and grief counseling determined that individuals' participation in death education does not always help them cope with death and grief, but that individuals can be significantly helped in the face of death and loss if individual differences in coping with grief are focused on and helping skills are developed.\n\nIt is thought that the awareness-based death-themed psychoeducation program to be applied to nurses in line with their educational needs will increase nurses' death awareness and reduce their death anxiety levels. The nurses working at Kastamonu Education and Research Hospital will constitute the universe of the study. The research will be conducted with nurses in a pre-test-post-test, experimental and control group experimental design. A power analysis will be conducted to determine the number of people to be included in the sample.\n\nIt will be calculated with G\\*Power 3.1 program. In the sample calculation, effect size (d=1.1), 5% margin of error (α=0.05) and power (1-β=0.95) were taken into account and 30 people were needed in the groups, 15 experimental and 15 control. However, considering the data loss, the sample size for each group was increased by 20% and it was planned to include 18 people in each group, a total of 36 people in the sample. In addition to descriptive statistical methods (Mean, Standard deviation) in the evaluation of the data, correlation test will be used to evaluate the relationship between the mean scores before and after the education in the comparison of quantitative data. Wilcoxon Associated Sample Test will be used to make comparisons before and after the education. ''Nurses Descriptive Information Form'', ''Multidimensional Death Awareness Scale'' and ''Thorson Powell Death Anxiety Scale'' will be used in the collection of data. A mindfulness-based psychoeducation program will be applied to the experimental group. The aim of the psychoeducation is to reduce the death anxiety of the nurses and to increase their awareness of death by providing them with information about the death experience they are secondarily exposed to (1- Death process and death anxiety, 2- Effects of the death process on the individual and family, 3- Coping with the death process, 4- Effects of the death process on caregiving nurses, 5- Awareness of death, 6- Nursing care and emotional competence during the death process). Therefore, it will be evaluated whether the applied psychoeducation program reduces the intended death anxiety and creates awareness about death. This study will be conducted to examine the effect of a 6-week, 12-session mindfulness-based group psychoeducation program given to nurses on death anxiety and death awareness levels.",[29,186],"Death Occurring in Intensive Care Units",[29,188,189],"death awareness","Nurse","2025-04-26",{"date":192,"type":40},"2025-05-04",{"date":194,"type":22},"2025-05-10",{"date":196,"type":22},"2025-07-10",{"name":198,"class":47},"Kastamonu University",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":104,"enrollmentInfo":206,"targetDuration":4,"studyType":23,"phases":208,"briefSummary":209,"conditions":210,"keywords":211,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":218,"leadSponsor":220,"locationsCount":4},"100578415","from-fear-to-purpose-act-protocol-implications-of-death-anxiety-in-depression-and-anxiety-symptoms-100578415","NCT06810999","From Fear to Purpose ACT Protocol. Implications of Death Anxiety in Depression and Anxiety Symptoms.","From Fear to Purpose ACT Protocol: Testing Indirect, Transdiagnostic Implications of Death Anxiety Over Depression and Anxiety. A Randomized Placebo Controlled Trial.","Inclusion Criteria:\n\n* Moderate-high levels of death anxiety (score \\> or = 55) AND\n* Subclinical levels of depression (score \\> or = 9) AND\u002FOR\n* Subclinical levels of anxiety (score \\> or = 9)\n\nExclusion Criteria:\n\n* Minors\n* Suicidal ideation\n* Current psychological\u002Fpsychiatric diagnosis (except depression or anxiety diagnosis)\n* Active psychological\u002Fpsychiatric treatment",{"count":207,"type":22},175,[25],"The main purpose of this placebo controlled trial is to test the efficacy of a one-session From Fear to Purpose ACT intervention in reducing self-reported death anxiety levels. Another objective of this study is to investigate whether reductions in death anxiety levels are associated with reductions in depression and anxiety levels, thus testing if death anxiety is a transdiagnostic factor involved in psychopathology.",[29,110,111],[113,114,115,116,212,213],"indirect intervention","rct","2025-04-16",{"date":216,"type":40},"2025-04-18",{"date":148,"type":22},{"date":219,"type":22},"2025-12-30",{"name":126,"class":47}]