[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"decision-aid\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:decision-aid":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,41,74,108,142,162],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100642269","improving-decision-making-for-missing-upper-front-teeth-100642269",false,"NCT07655193","Improving Decision-Making for Missing Upper Front Teeth","Development of a Patient Decision Aid for the Treatment of Maxillary Lateral Incisor Agenesis","Patient Participant Inclusion Criteria:\n\n* Young people with Maxillary Lateral Incisor Agenesis (MLIA) affecting one or both maxillary lateral incisors\n* Young people aged 11-18 years old (attending with an adult with parental responsibility if \\\u003C16 years old)\n* In active orthodontic (space-closure or space-opening) or restorative treatment for MLIA, or completed active dental treatment less than one year ago\n* Attended a multidisciplinary Hypodontia Clinic for treatment planning where both space-closure and space-opening options were offered\n\nPatient Participant Exclusion Criteria:\n\n* Craniofacial anomalies including cleft lip and\u002For palate\n* Unable to communicate in English where no professional translation service is available\n\nClinician Participant Inclusion Criteria:\n\n* Specialists or consultants in orthodontics, restorative dentistry, paediatric dentistry, and oral surgery who provide care as part of the Hypodontia pathway and work within the multidisciplinary hypodontia clinics\n\nClinician Participant Exclusion Criteria:\n\n* Any clinician not providing care as part of the Hypodontia pathway and working within the multidisciplinary hypodontia clinics",true,"ALL","11 Years","18 Years",{"count":21,"type":22},20,"ESTIMATED","OBSERVATIONAL","Background: The developmental absence of 1-2 upper front teeth is a common condition, affecting 1 in 50 people worldwide, and affects smile aesthetics and quality-of-life. Treatment is often undertaken in teenagers, but the outcomes have lifelong consequences. Treatment options involve either creating space for a false tooth, or closing space and disguising the adjacent tooth as the missing tooth; both options have their own advantages, disadvantages and long-term considerations, and treatment often requires input from multiple dental specialties. Advances in orthodontic techniques mean more patients can be treated with either approach, therefore, the ideal treatment plan becomes more subjective and based upon the patient's preferences.\n\nAim: To develop a Patient Decision Aid (PDA), a decision-making support tool to help young people (and parents\u002Fguardians) with developmentally missing upper front teeth choose the best treatment option for them.\n\nApproach: First, the investigators will gather information from stakeholders involved in the decision-making process to understand their needs. Interviews will be conducted with young people with developmentally missing upper front teeth and their parents\u002Fguardians about their experiences, expectations, and preferences regarding treatment decision-making. Information will also be sought from clinicians involved in this process about their experiences of the decision-making process, via focus groups. These will be carried out across two NHS hospitals with special clinics for missing teeth. Then, the information obtained from both patient and clinician stakeholder groups will help the investigators to develop a PDA, following international guidelines. PDA development will occur alongside ongoing input and feedback from a Development Panel (which will include patients and clinician representatives) to optimise content, acceptability, and accessibility. The final approved PDA will then be trialled in a later pilot study.",[26,27,28],"Hypodontia","Decision Making ,Shared","Decision Aid","NOT_YET_RECRUITING","2026-06-15",{"date":32,"type":33},"2026-06-17","ACTUAL",{"date":35,"type":22},"2026-08-01",{"date":37,"type":22},"2028-08-31",{"name":39,"class":40},"King's College London","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100598505","videos-to-aid-decision-making-for-fibroid-treatment-100598505","NCT07072364","Videos to Aid Decision Making for Fibroid Treatment","The Use of Video Aids Versus Usual Care for Reduction in Decisional Conflict in Fibroid Treatment","Fibroid AUB","Inclusion Criteria:\n\n* Diagnosis of uterine fibroids\n* Scheduled appointment to discuss management of fibroids in an outpatient clinical site associated with the Hospital of the University of Pennsylvania\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>55\n* Uterine or cervical cancer\n* Cervical dysplasia grade 2-3 within the last 12 mo\n* Pregnancy\n* Menopause\n* Decision made prior to the study intake to have a surgical procedure for treatment of fibroids","55 Years",{"count":51,"type":22},154,"INTERVENTIONAL",[54],"NA","Uterine fibroids are a common condition that can cause heavy and\u002For painful menstrual bleeding. There are many treatment options, but they vary in efficacy, side effects, short-term recovery and long-term implications for future fertility. Patients can have difficulty deciding between these options. In this study, the investigators will randomly assign patients seeking treatment for fibroids to receive an educational video on fibroids and their treatment, versus usual care (no video). The investigators will assess their decisional conflict with and without exposure to the video using a validated survey to see if exposure to the educational video helps them make decisions.",[57,28],"Uterine Bleeding",[59,60,61,62],"Abnormal uterine bleeding","Uterine fibroids","Decisional Conflict Scale","Educational videos","RECRUITING","2026-04-29",{"date":66,"type":33},"2026-05-01",{"date":68,"type":33},"2025-03-12",{"date":70,"type":22},"2026-07",{"name":72,"class":40},"University of Pennsylvania",1,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":82,"minAge":19,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":52,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100631175","decision-aid-for-women-newly-diagnosed-with-breast-cancer-100631175","NCT07497256","Decision Aid for Women Newly Diagnosed With Breast Cancer","Effectiveness and Cost-effectiveness of a Multimodal Shared Decision-Making Decision Aid ( BCT Aid) for Women Newly Diagnosed With Breast Cancer","BCT Aid","Inclusion Criteria:\n\n1. Age ≥ 18 years.\n2. Newly diagnosed with breast cancer, with clinical stage 0-II, or stage III eligible for breast-conserving surgery after neoadjuvant chemotherapy.\n3. Clinically eligible for breast-conserving surgery and considering one of the following surgical options: breast-conserving surgery, mastectomy, or mastectomy with reconstruction.\n4. Clinically eligible for adjuvant therapy after surgery.\n5. Able to access the internet via smartphone.\n6. Able to read, speak, and understand Mandarin.\n\nExclusion Criteria:\n\n1. Male breast cancer patients.\n2. Clinically eligible for only one surgical option or not candidates for surgery.\n3. Have a history of other malignancies, except adequately treated cervical carcinoma in situ and basal cell carcinoma of the skin.\n4. Presence of psychiatric disorders, visual or hearing impairments, or cognitive impairment.","FEMALE",{"count":84,"type":22},160,[54],"The goal of this multi-center randomized controlled trial is to determine if the clinical decision aid (BCT Aid) works to help breast cancer patients participate in decision-making and make high-quality decisions, thereby improving the rate of breast-conserving surgery and quality of life. The main questions it aims to answer are:\n\nDoes the BCT Aid significantly increase the rate of breast-conserving surgery compared to usual care? Does the BCT Aid reduce decision conflict and decision regret, while improving shared decision-making and quality of life? Does the BCT Aid demonstrate better cost-effectiveness in terms of health resource utilization? Researchers will compare the BCT Aid to usual care (standard clinical consultation) to evaluate the effectiveness and cost-effectiveness of BCT Aid.\n\nParticipants will:\n\nBe randomly assigned to either the intervention group (receiving the BCT Aid intervention for 6 months) or the control group (usual care).\n\nComplete assessments including decision conflict and shared decision-making at baseline (T0), post-consultation with the surgeon (T1), 6 months (T2, post-intervention), and 12 months (T3, 6 months post-intervention), decision regret at T2 and T3, and quality of life at T0, T2, and T3, with additional EQ-5D-5L measurements at baseline, 3, 6, 9, and 12 months for cost-effectiveness analysis.\n\nHave clinical outcomes (breast-conserving surgery rate) and health resource utilization data collected from medical records.",[88,28,89,90,91],"Breast Cancer","Shared Decision Making","Cost Effectiveness","Quality of Life",[93,94,95,96,97],"breast cancer","decision aid","decision conflict","shared decision making","cost effectiveness","2026-04-26",{"date":100,"type":33},"2026-04-30",{"date":102,"type":22},"2026-04-01",{"date":104,"type":22},"2027-10",{"name":106,"class":40},"Xiamen University",3,{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":82,"minAge":116,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":52,"phases":119,"briefSummary":120,"conditions":121,"keywords":127,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":73},"100634727","decision-aid-for-elective-egg-freezing-100634727","NCT07543445","Decision Aid for Elective Egg Freezing","Knowledge, Decision-making, and Oocyte Cryopreservation Outcomes in Taiwanese Women Considering Elective Egg Freezing: a Randomized Controlled Trial","DAEEF","Inclusion Criteria:\n\n* Women aged 20 years or older.\n* Currently considering elective egg freezing (EEF).\n* Able to communicate and read Chinese fluently.\n* Have access to the internet and a mobile device (smartphone, tablet, or computer) to complete online questionnaires.\n\nExclusion Criteria:\n\n* Individuals who have previously completed oocyte cryopreservation.\n* Women undergoing fertility preservation due to malignancy (i.e., breast cancer).\n* Postmenopausal women.","20 Years",{"count":118,"type":22},120,[54],"The goal of this clinical trial is to evaluate whether a culturally tailored decision aid can improve decision-making and clinical outcomes for Taiwanese women considering elective egg freezing.\n\nThe main questions it aims to answer are:\n\nDoes the decision aid improve women's knowledge about elective egg freezing and help clarify their personal values? Does the decision aid reduce decision regret and psychological distress after making a decision about egg freezing?\n\nResearchers will compare women who use the decision aid with those who receive standard counseling to see if the tool improves knowledge, reduces distress and regret, and leads to better clinical outcomes (such as completing egg freezing or achieving a higher number of frozen oocytes).\n\nParticipants will:\n\n* Complete questionnaires assessing their baseline knowledge, attitudes, and values regarding egg freezing\n* Receive either the decision aid or standard counseling\n* Complete follow-up questionnaires to assess knowledge, distress, and decision regret\n* Have their clinical outcomes recorded, including whether they undergo egg freezing and the number of oocytes retrieved and frozen",[122,123,28,124,89,125,126],"Elective Egg Freezing","Oocyte Cryopreservation","Egg Freezing","Assisted Reproductive Technology","Fertility Preservation",[128,129,130,94,96,131,132],"elective egg freezing","planned oocyte cryopreservation","fertility preservation","assisted reproductive technology","randomized controlled trial","2026-04-15",{"date":135,"type":33},"2026-04-21",{"date":137,"type":22},"2026-04-13",{"date":139,"type":22},"2031-12-31",{"name":141,"class":40},"National Taiwan University Hospital",{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":52,"phases":150,"briefSummary":151,"conditions":152,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":157,"completionDateStruct":158,"leadSponsor":160,"locationsCount":73},"100631788","informing-patients-about-their-surgerys-environmental-impact-an-effective-pathway-to-sustainable-healthcare-100631788","NCT07505238","Informing Patients About Their Surgery's Environmental Impact: an Effective Pathway to Sustainable Healthcare?","Inclusion Criteria:\n\n* Patients who were referred to three participating hospitals located across the Netherlands\n* Patients who received PatientPlus' gallstone decision aid in preparation for their surgical consultation\n\nExclusion Criteria:\n\n* None",{"count":149,"type":22},400,[54],"The healthcare sector contributes significantly to climate change. Reducing the number of patients receiving resource-intensive procedures such as surgery can lower carbon emissions, particularly when two treatments with comparable clinical outcomes are available. Nevertheless, the impact of incorporating environmental considerations into patients' decision-making processes remains underexplored. The investigators examine how including information about the environmental impact of treatment options in a gallstone decision aid affects patients' real-life choice between surgery and the more sustainable alternative of conservative treatment. Moreover, the investigators examine whether factors such as severity of symptoms moderate the relation between sustainability information and patients' treatment choice. An exploratory vignette study informed the hypotheses that will be tested among actual patients with gallstones making actual treatment decisions. The results of this ecologically valid study have implications for both clinical practice and healthcare policy by offering insight into the effectiveness of pathways to include patients in the transition towards sustainable healthcare.",[153,154,28,27],"Sustainability","Gallstone","2026-03-25",{"date":102,"type":33},{"date":102,"type":22},{"date":159,"type":22},"2027-07-01",{"name":161,"class":40},"University of Amsterdam",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":168,"eligibilityCriteria":169,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":170,"enrollmentInfo":171,"targetDuration":4,"studyType":52,"phases":173,"briefSummary":174,"conditions":175,"keywords":183,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":4},"100516284","relief-pathway-in-patients-with-upper-abdominal-pain-100516284","NCT06002516","RELIEF-pathway in Patients With Upper Abdominal Pain","The RELIEF-pathway in Patients With Upper Abdominal Pain; an Open-label Multicenter Randomized Controlled Trial","RELIEF","Inclusion Criteria:\n\n* Patients between 18 and 70 years old.\n* First referral due to upper abdominal pain (UAP) and symptoms due to Functional dyspepsia (ICPC code 87.02), Irritable Bowel syndrome (ICPC 93.0) or uncomplicated symptomatic cholecystolithiasis (ICPC 98.03).\n* Proficient in reading and understanding of the Dutch language.\n* Referred to the outpatient clinic of gastroenterology or surgery.\n* Providing informed consent.\n\nExclusion Criteria:\n\n* If the following alarm symptoms are reported in the referral letter by the GP: weight loss, persistent vomiting, dysphagia, jaundice, hematemesis, melena, haematochezia, or anaemia.\n* Any other direct or indirect signs of cancer or upper GI tract bleeding.\n* Patients with a first or second-degree relative with a history of upper GI tract malignant neoplasm.\n* Patients with a history of complicated cholecystolithiasis.\n* A history of or current malignancy (except SCC or BCC of the skin).\n* Pregnancy;\n* Expected short life span of less than 12 months.\n* Known cirrhosis of the liver\n* Current schizophrenia, memory deficiency, or any other disorder that predispose them to unreliable questionnaire responses;\n* Mentally incompetent;","70 Years",{"count":172,"type":22},471,[54],"Upper abdominal pain (UAP) is a common symptom and frequently the reason to visit the hospital. The prevalence of epigastric pain in the Dutch population is estimated to be as high as 37%. Moreover, Dutch hospitals yearly record \\>100.000 diagnoses related to UAP. In most patients, UAP can be attributed to symptomatic (functional) dyspepsia (FD), Irritable Bowel Syndrome (IBS) or uncomplicated gallstone disease (cholecystolithiasis), with a prevalence in the general population of 20-30%, 20%, and 6-9%, respectively. However, these conditions may have overlapping symptom patterns and generally affect similar populations. which contributes to ineffective (diagnostic) interventions. Patients are generally not aware of the similarity of symptoms and the poor outcome of some treatments.\n\nEducation positively influences patients' self-management and health judgment. In a recent open-label, multicentre trial the effectiveness of web-based patients' education is applied to reduce overuse of upper gastrointestinal endoscopies in patients with dyspepsia. This study illustrated that an web-based education tool safely reduced 40% in upper gastrointestinal endoscopies. Lifestyle interventions (such as change of diet and\u002For physical activity) are widely incorporated in treatment programs for cardio-vascular diseases including diabetes mellitus and obesity. An web-based education tool on upper abdominal pain and other complaints combined with a lifestyle interventions for patients may be an effective treatment option for this large group of patients.\n\nThis study investigates the potential of an individualized web-based education tool as intervention for patients with functional dyspepsia, irritable bowel syndrome and uncomplicated symptomatic cholecystolithiasis with the possibility to visit the Prevention and Lifestyle clinic (RELIEF pathway). The RELIEF pathway aims to reduce unnecessary health care utilization and, secondly, to maintain and improve quality of life by educating patients on lifestyle improvement.",[176,177,178,179,180,181,182,28],"Abdominal Pain","Gallstone; Colic","Dyspepsia","Irritable Bowel Syndrome","Health Care Utilization","Patient Reported Outcomes","Upper Abdominal Pain",[184,185],"Abdominal pain","Health care utilization","2023-08-15",{"date":188,"type":33},"2023-08-21",{"date":190,"type":22},"2024-05-01",{"date":192,"type":22},"2027-05-01",{"name":194,"class":40},"Radboud University Medical Center"]