[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"decision-making\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:decision-making":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,22,0,[8,60,105,169,202,233,258,283,305,335,357,385,425,449,479,505,527,560,587,617,639,675],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100053649","phosphatidylserine-taurine-and-caffeine-for-cognitive-fatigue-in-professional-football-players-100053649",false,"NCT07696052","Phosphatidylserine, Taurine, and Caffeine for Cognitive Fatigue in Professional Football Players","Neurocognitive Fatigue Resistance, Visual Search Efficiency, and Tactical Decision-Making After Phosphatidylserine-Containing Taurine-Caffeine Supplementation in Professional Male Football Players","TCPS-Foot","Inclusion Criteria:\n\n* Male professional outfield football players aged 18 to 37 years.\n* First-team players or selected U19 players aged 18 years or older who are regularly integrated into first-team training.\n* Regular participation in club training.\n* At least 5 years of systematic football training experience.\n* Free from injury or illness limiting full participation in training and testing.\n* Normal or corrected-to-normal vision.\n* Ability to complete the laboratory and field-based testing procedures.\n* Written informed consent provided before participation.\n\nExclusion Criteria:\n\n* Goalkeepers.\n* Current injury or illness limiting full participation in testing.\n* Neurological disease.\n* Recent concussion or head trauma.\n* Uncorrected visual impairment.\n* Use of phosphatidylserine, nootropic agents, or strong stimulants during the previous 4 weeks.\n* Non-standard caffeine intake on testing days.\n* Failure to comply with pre-test standardization procedures.\n* Failed eye-tracker calibration.\n* Loss of more than 30% of gaze data during the football-specific decision-making task.\n* Withdrawal of consent.",true,"MALE","18 Years","37 Years",{"count":22,"type":23},62,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized, double-blind, placebo-controlled, parallel-group trial will evaluate the effects of 14 days of taurine-caffeine supplementation with or without phosphatidylserine on neurocognitive fatigue resistance, visual search efficiency, and football-specific tactical decision-making in professional male football players. Sixty-two male outfield football players from two professional clubs will be randomized to placebo, taurine plus caffeine, or taurine plus caffeine plus phosphatidylserine. Laboratory and field-based outcomes will be assessed at baseline and after the supplementation period.",[29,30,31,32,33],"Mental Fatigue","Cognitive Performance","Athletic Performance","Soccer Performance","Decision Making",[35,36,37,38,39,40,41,42,43,44,45,46],"Phosphatidylserine","Taurine","Caffeine","Football Players","Soccer","Neurocognitive Load","Visual Search","Eye Tracking","Tactical Decision-Making","Stroop Flanker Task","Reactive Passing Decision Test","Sports Nutrition","NOT_YET_RECRUITING","2026-07-09",{"date":50,"type":51},"2026-07-13","ACTUAL",{"date":53,"type":23},"2026-07",{"date":55,"type":23},"2026-08",{"name":57,"class":58},"Vizja University in Warsaw","OTHER",2,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":17,"sex":66,"minAge":19,"maxAge":4,"enrollmentInfo":67,"targetDuration":4,"studyType":24,"phases":69,"briefSummary":70,"conditions":71,"keywords":83,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100635793","supporting-just-in-time-consent-for-prenatal-screening-the-inform-study-100635793","NCT07557303","Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study","Inclusion Criteria:\n\n* Currently pregnant and receiving care at a participating collaborative site - University of North Carolina, Chapel Hill; Zuckerberg Chan San Francisco General Hospital; University of Florida Health, Jacksonville.\n* 18 years of age and older\n* Able to read, speak, and understand English or Spanish\n* Has not previously been offered prenatal genetic screening for the current pregnancy\n* 24 weeks (6 months) gestational age or less\n\nExclusion Criteria:\n\n* Not pregnant, not a patient at a partner clinical site\n* Younger than 18 years of age\n* Not being able to read, speak, and understand English or Spanish\n* Has previously been offered prenatal genetic screening for the current pregnancy\n* Greater than 24 weeks gestational age (6 months)","FEMALE",{"count":68,"type":23},1400,[26],"This clinical trial is about prenatal genetic screening. It will test an intervention to help people make decisions about screening. The intervention is a short set of information cards about screening. This intervention is for pregnant participants. They will use the intervention on their mobile phone before they see their doctor.\n\nThe study has one main question:\n\n* Do participants who use the intervention feel more confident when they make a decision about screening?\n\nResearchers will compare participants who use the intervention to participants who do not. All participants will have their usual care when they visit their doctor.\n\nWhat will participants do?\n\n* Participants must be pregnant. They will sign up for the study before their first doctor's visit for their pregnancy. This is the visit where their doctor usually talks with them about screening.\n* Some participants will use the intervention before their first doctor's visit. Other participants will not use it.\n* All participants will talk with a researcher on the phone after their first doctor's visit.\n* Participants who use the intervention will answer a short survey on their phone.\n* A few participants who use the intervention will talk with a researcher a second time on the phone.",[72,73,74,75,76,77,78,79,80,33,81,82],"Delivery of Health Care","Genetic Testing","Humans","Pregnancy","Noninvasive Prenatal Testing","Informed Consent","Internet-Based Intervention","Self Efficacy","Pregnant People","Health Education","Patient Education as Topic\u002FMethod",[84,85,86,87,88,89,90,91,92,93,94],"Non-invasive prenatal screening (NIPS)","Non-Invasive Prenatal Testing (NIPT)","Cell-free DNA (cfDNA)","Prenatal genetic screening","Informed consent","Decision making","Surveys and Questionnaires","Informed choice","Educational intervention","Decision Regret","Decision Satisfaction","2026-06-30",{"date":97,"type":51},"2026-07-01",{"date":99,"type":23},"2026-08-01",{"date":101,"type":23},"2028-06-30",{"name":103,"class":58},"Case Western Reserve University",3,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":17,"sex":112,"minAge":113,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":24,"phases":117,"briefSummary":118,"conditions":119,"keywords":147,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":168},"100454745","interventions-in-mathematics-and-cognitive-skills-100454745","NCT05201534","Interventions in Mathematics and Cognitive Skills","Interventions in Math Learning Disabilities: Cognitive and Neural Correlates","Inclusion Criteria:\n\n1. Elementary school aged children starting from first grade (6-12 years old)\n2. IQ: Participants with a Full Scale IQ \\> 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).\n3. Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests\n4. Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests\n5. Normal or corrected-to-normal vision and no hearing impairments\n6. Inclusion in MRI scan session: Right-handed\n\nExclusion Criteria:\n\n1. History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)\n2. History of trauma involving head injury\n3. Consistent psychiatric medications\n4. Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)","ALL","6 Years","12 Years",{"count":116,"type":23},180,[26],"The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).",[120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,33,135,136,137,138,139,140,141,142,143,144,145,146],"Math Learning Disability","Child Development","Developmental Disability","Learning Disabilities","Learning Disabled","Learning Curve","Mathematics Disorder","Dyscalculia","Dyscalculia, Primary","Dyscalculia, Acquired","Specific Learning Disorder, With Impairment in Mathematics","Individuality","Behavior, Child","Behavior and Behavior Mechanisms","Behavior","Neuronal Plasticity","Cognition","Cognition Disorder","Cognitive Dysfunction","Cognitive Change","Cognitive Impairment, Mild","Cognitive Developmental Delay","Cognitive Orientation","Cognitive Delay, Mild","Cognitive Deficits, Mild","Cognitive Abnormality","Neuroscience",[148,149,150,151,152,153,154,155,156,157],"Numerical skills in children","Low math abilities","Mathematical Learning Disabilities","Mathematical Concepts","Mathematics","Transfer, Psychology","Generalization, Psychology","Early Intervention, Educational","Neural Pathways","Neural Networks, Computer","RECRUITING","2026-06-22",{"date":161,"type":51},"2026-06-25",{"date":163,"type":51},"2023-05-05",{"date":165,"type":23},"2026-08-31",{"name":167,"class":58},"Stanford University",1,{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":24,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":168},"100544950","k-orca-testing-a-decision-support-tool-and-group-process-for-selecting-interventions-100544950","NCT06375551","K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions","Refining and Pilot Testing a Decision Support Intervention to Facilitate Adoption of Evidence-Based Programs to Improve Parent and Child Mental Health","K-ORCA","Inclusion Criteria:\n\n* Non-institutionalized\n* Adults (18 years or older).\n* English-Speaking\n\nAim 1:\n\n* Involved in initial state decision-making related to Family First Prevention Services Act.\n* Willing to participate in two data collection occasions.\n\nAim 2:\n\n* Non-institutionalized\n* Adults (18 years or older). English-Speaking.\n* Involved in ongoing state decision-making related to Family First Prevention Services Act.\n* Willing to participate in three measurement occasions.\n\nAim 3:\n\n-Willing to participate in multiple (bi-weekly up to two years) measurement occasions.\n\nExclusion Criteria:\n\n-Not involved in or potentially influencing child welfare intervention decisions",{"count":178,"type":23},80,[26],"This proposal responds to NIMH Objective 4.2.c to develop \"decision-support tools and technologies that increase the effectiveness and continuous improvement of mental health interventions\" by leveraging the Family First Prevention Services Act (FFPSA) policy opportunity. First, a web-based platform to host (a) a decision-support tool and (b) automated facilitation for group decisions with the tool will be developed with state partners' feedback. Next, decision makers leading their states' FFPSA quality improvement efforts will be engaged to pilot a decision-support intervention comprised of the tool and live or automated facilitation, and to evaluate the implementation quality of evidence-based programs adopted with the decision-support intervention.",[182,33,183,184,185,186,187,188,189,190,191,192],"Child Abuse","Child Welfare","Decision Making, Shared","Decision Support Technique","Social Facilitation","Implementation Science","Policy","Organizations","Consensus","Mental Health","Family","2026-06-16",{"date":195,"type":51},"2026-06-18",{"date":197,"type":23},"2026-12-01",{"date":199,"type":23},"2027-07-31",{"name":201,"class":58},"Chestnut Health Systems",{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":209,"enrollmentInfo":210,"targetDuration":4,"studyType":24,"phases":212,"briefSummary":213,"conditions":214,"keywords":219,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":229,"leadSponsor":231,"locationsCount":4},"100643285","the-influence-of-obesity-and-insulin-sensitivity-on-reward-processing-and-decision-making-100643285","NCT07638059","The Influence of Obesity and Insulin Sensitivity on Reward Processing and Decision Making","No acronym","Inclusion Criteria:\n\n* 18 to 45 years of age\n* Self-reported weight stable (within 5 lbs) for previous 3 months\n* Not pregnant or planning to become pregnant during study participation\n* Weigh more than 110 lbs (due to blood draws used in study)\n* Residing in Roanoke, VA, area and\u002For willing to attend sessions at the Fralin Biomedical Research Institute\n\nExclusion criteria:\n\n* BMI \\\u003C 18.5 or \\> 40 kg\u002Fm2\n* Hemoglobin A1c \\> 6.4%\n* Fasting blood glucose \\> 126 mg\u002FdL\n* 2-hour blood glucose \\> 200 mg\u002FdL\n* Self-reported current diagnosis of diabetes or other endocrine\u002Fmetabolic disorder\n* Self-reported current inhaled nicotine use\n* Self-reported history of alcohol dependence\n* Self-reported use of medications known to influence study measures (including antiglycemic agents, thyroid medications, etc.)\n* Self-reported neurological or psychological disorder\n* Self-reported claustrophobia or discomfort with mock fMRI training\n* Self-reported history of head injury resulting in loss of consciousness for more than 10 minutes\n* Contraindications to MRI, including pacemaker, aneurysm clip, neurostimulator, cochlear implant, metal in eyes, steel worker, other implants\n* Self-reported previous metabolic\u002Fweight loss surgery\n* Self-reported adherence to special or restrictive diet within the past 3 months (e.g., low-carb, ketogenic, exclusion of food groups\u002Fspecific macronutrients, etc.)\n* Self-reported allergy to ingredient used in the study drinks","45 Years",{"count":211,"type":23},50,[26],"Reward learning and decision-making processes, which operate largely outside of conscious control, shape food choices and eating behaviors. Excess adiposity is associated with differences in brain structure and functional connectivity underlying these processes, and insulin resistance, which commonly co-occurs with excess adiposity, has been linked with dopamine signaling that is crucial for these processes. However, whether and how excess adiposity and insulin resistance affect reward learning and decision-making remains poorly understood. This study will address that gap, examining the effects of excess adiposity and insulin resistance, and their interaction, on processes of reward learning and decision-making in food-specific and general contexts.",[215,216,217,218],"Adiposity","Insulin Sensitivity\u002FResistance","Decision-Making","Reward Learning",[220,221,222,223,224],"flavor nutrient learning","insulin sensitivity","adiposity","decision-making","probabilistic learning","2026-06-05",{"date":227,"type":51},"2026-06-10",{"date":97,"type":23},{"date":230,"type":23},"2029-07-01",{"name":232,"class":58},"Virginia Polytechnic Institute and State University",{"id":234,"slug":235,"hasResults":11,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":4,"eligibilityCriteria":239,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":4,"enrollmentInfo":240,"targetDuration":4,"studyType":24,"phases":242,"briefSummary":243,"conditions":244,"keywords":245,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":168},"100549939","craving--decision-making-100549939","NCT06440577","Craving & Decision-Making","Decision Neuroscience of Craving","Inclusion Criteria:\n\n* At least 18 years of age\n* Willingness to follow study requirements, as evidenced by an ability to provide written informed consent and read, understand, and complete the study procedures\n* Minimum of 6th grade reading level\n\nAdditional inclusion criteria for participants with OUD:\n\n* Primary diagnosis of OUD encompassing heroin and\u002For painkiller use\n* Receiving medications for OUD treatment on an outpatient basis\n* At least 12-month history of opioid use\n\nExclusion Criteria:\n\n* Unable to speak or read English\n* Active psychosis or mania\n* Current or past schizophrenia diagnosis\n* History of intellectual disability or developmental or neurological disorder, seizures or epilepsy, or loss consciousness lasting more than 30 minutes\n* Severe medical conditions requiring hospitalization or that, in the opinion of the study staff could compromise study participation\n* MRI contraindications (claustrophobia, nonremovable piercings, certain metal in the body etc.) or pregnancy\n\nAdditional exclusion criteria for community control participants:\n\n* Positive urine drug screen\n* Current or past problematic substance use other than nicotine, and alcohol abuse confined to college or military service\n* Current or past bipolar disorder diagnosis\n* Use of central nervous system medications within the past 6 weeks (e.g., antidepressants, Ritalin)",{"count":241,"type":23},160,[26],"Craving is the strong desire for something, such as for substances in drug addiction and food or other activities in everyday life. Recent work suggests craving can influence how people make decisions and assign value to choice options available to them, yet the neural mechanisms underlying these interactions between craving and valuation remain unknown. To address this, this study uses cognitive decision-making tasks that measure how much individuals will pay (from a study endowment) to have everyday consumer items or snack foods when they crave something specific (opioids or a specific snack, respectively). First, the study will identify the neural mechanisms for how drug craving (craving for opioids) interacts with valuation for consumer items that have associations with drug use or not in people receiving treatment for opioid use disorder (OUD). This will be evaluated in the activity patterns and interactions among brain regions involved in craving and value assignment during decision-making. Then, the study will examine for parallel mechanisms for how food craving (craving for a specific snack) interacts with valuation for snack food items that have similar features to the craved snack or not in people receiving treatment for OUD and non-psychiatric community control participants.",[33],[246,33,247,248],"Craving","Opioid Use Disorder","Dietary Choice","2026-06-02",{"date":251,"type":51},"2026-06-04",{"date":253,"type":51},"2024-06-18",{"date":255,"type":23},"2027-12",{"name":257,"class":58},"Rutgers, The State University of New Jersey",{"id":259,"slug":260,"hasResults":11,"nctId":261,"briefTitle":262,"officialTitle":262,"acronym":263,"eligibilityCriteria":264,"healthyVolunteers":11,"sex":112,"minAge":265,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":24,"phases":269,"briefSummary":270,"conditions":271,"keywords":4,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":274,"lastUpdatePostDateStruct":275,"startDateStruct":277,"completionDateStruct":279,"leadSponsor":281,"locationsCount":168},"100565159","integrating-telehealth-to-advance-lung-cancer-screening-100565159","NCT06638554","Integrating Telehealth to Advance Lung Cancer Screening","ITALCS","Inclusion criteria:\n\nParticipants will be eligible if:\n\n1. are aged 50 to 80\n2. have a history of tobacco use indicated by either: Documented 20 pack-year or greater smoking history in their electronic health record (EHR); OR Self-report via structured survey\n3. currently smoke or formerly smoked cigarettes\n4. have no documented history of lung cancer\n5. have no documented history of lung cancer screening in the 24 months prior to study enrollment\n6. have completed at least one primary care visit at Penn Medicine in the 3 years prior to study enrollment.\n\nExclusion criteria:\n\nParticipants who do not meet inclusion criteria will not be eligible.","50 Years","80 Years",{"count":268,"type":23},6000,[26],"The goal of this pragmatic trial is to learn if telehealth strategies can increase shared decision-making (SDM) for lung cancer screening (LCS). It will also learn about the equity of these strategies by conducting non-inferiority analysis by race and sex. The main questions it aims to answer are:\n\n1. Does patient outreach using synchronous and asynchronous telehealth strategies increase completion of SDM visits for LCS?\n2. Is the effectiveness of these telehealth strategies similar by race and sex?\n\nThe study uses a Sequential Multiple Assignment Randomized Trial (SMART) design and includes two stages of interventions. The first stage of intervention includes direct patient outreach with an invitation to schedule either a 1) telehealth SDM visit or 2) telehealth or in-person SDM visit. Participants that do not respond to the first stage interventions receive a text message reminder encouraging SDM visit completion with or without digital care coordination.",[272,273,33],"Early Detection of Cancer","Telemedicine","2026-05-27",{"date":276,"type":51},"2026-05-29",{"date":278,"type":51},"2024-07-09",{"date":280,"type":23},"2027-06-30",{"name":282,"class":58},"Abramson Cancer Center at Penn Medicine",{"id":284,"slug":285,"hasResults":11,"nctId":286,"briefTitle":287,"officialTitle":287,"acronym":288,"eligibilityCriteria":289,"healthyVolunteers":11,"sex":112,"minAge":4,"maxAge":4,"enrollmentInfo":290,"targetDuration":4,"studyType":24,"phases":292,"briefSummary":293,"conditions":294,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":301,"leadSponsor":303,"locationsCount":104},"100622988","building-relationship-improving-dialogue-and-growing-empathy-bridge-an-intervention-to-support-decision-making-for-critically-ill-children-100622988","NCT07390773","Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children","BRIDGE","Inclusion Criteria:\n\nChild inclusion criteria will include:\n\n* Age \\\u003C 5 years\n* Admission to a critical care unit within the preceding 14 days\n* An anticipated serious health care decision, defined as a decision about initiating, not initiating, or withdrawing life-sustaining treatment and\u002For a decision about major intervention.\n\nParent inclusion criteria will include:\n\n* Age ≥ 18 years\n* The ability speak English or Spanish.\n\nClinician inclusion criteria will include\n\n* Clinical team member of an enrolled child and parent in the intervention group\n* Completion of residency or equivalent training.\n\nExclusion Criteria:\n\n* Children, parents or clinicians who do not meet the inclusion criteria above.",{"count":291,"type":23},495,[26],"Parents of young children in the intensive care unit may be faced with decisions about their child's care. The Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE) intervention was designed to help support parents as they make decisions for their child and communicate with the health care team. The main questions this study aims to answer are:\n\n1. Do parents who receive the BRIDGE intervention report being better prepared to make decisions for their child?\n2. Do parents who receive the BRIDGE intervention report less regret about the decisions they made for their child?\n\nParticipants will complete surveys at baseline and approximately 2 weeks, 6 months, and 12 months following enrollment. Some participants will also participate in interviews about their experiences.",[33,295,296],"Neonatal Critical Illness","Pediatric Critical Illness","2026-05-21",{"date":299,"type":51},"2026-05-22",{"date":53,"type":23},{"date":302,"type":23},"2028-10",{"name":304,"class":58},"Duke University",{"id":306,"slug":307,"hasResults":11,"nctId":308,"briefTitle":309,"officialTitle":309,"acronym":310,"eligibilityCriteria":311,"healthyVolunteers":11,"sex":112,"minAge":4,"maxAge":4,"enrollmentInfo":312,"targetDuration":4,"studyType":24,"phases":313,"briefSummary":314,"conditions":315,"keywords":318,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":333,"locationsCount":168},"100632785","the-effect-of-an-artificial-intelligence-supported-virtual-reality-simulation-on-nursing-students-holistic-care-skills-100632785","NCT07518199","The Effect of an Artificial Intelligence-Supported Virtual Reality Simulation on Nursing Students' Holistic Care Skills","AI-VRS","Inclusion Criteria:\n\n* Voluntary participation in the study,\n* Having enrolled for the first time in the courses HEM 402 Professional Practice I and HEM 404 Professional Practice II in the Department of Nursing, Faculty of Health Sciences,\n* Absence of eye conditions affecting depth perception, such as amblyopia (lazy eye), anisometropia(different refractive errors in each eye), and strabismus (squint). (Self- report is accepted.),\n* Academic performance score between 2.00 and 4.00.,\n\nExclusion Criteria:\n\n* Having received training in holistic care skills in addition to their undergraduate nursing degree,\n* Having experience with virtual simulation exercises focused on holistic care skills,\n* Holding a high school, foundation year or undergraduate degree in a health-related field,\n* Having difficulty understanding and speaking Turkish,\n\nCriteria for Exclusion from the Study:\n\n* The participant has not completed or has incompletely completed the required forms and scales,\n* The participant in the experimental group had not taken part in or completed the AI-supported virtual reality simulation,\n* Students in the control group did not take part in the educational case study,\n* Students in the experimental and control groups did not take part in the assessment case study,\n* The participant wishes to withdraw from the study,",{"count":178,"type":23},[26],"This study aims to evaluate the effect of artificial intelligence (AI)-supported virtual reality (VR) simulation on nursing students' holistic care skills. The study is a randomised controlled trial involving fourth-year nursing students, divided into an experimental and a control group. Whilst the experimental group will receive AI-supported VR simulation training, the control group will receive traditional case-based training. Outcomes to be assessed include decision-making, symptom identification, nursing diagnosis, simulation design and satisfaction with the training methods.",[316,217,317],"Nursing Students","Diagnostic Reasoning",[319,320,321,322,323,324,325],"Artificial Intelligence","Simulation Training","Immersive Virtual Reality","Nursing Education","Holistic Care","Nursing Diagnoses","Educational Technology","2026-04-04",{"date":328,"type":51},"2026-04-08",{"date":330,"type":23},"2026-04",{"date":332,"type":23},"2026-05",{"name":334,"class":58},"Gazi University",{"id":336,"slug":337,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":340,"eligibilityCriteria":341,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":342,"enrollmentInfo":343,"targetDuration":4,"studyType":24,"phases":344,"briefSummary":345,"conditions":346,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":349,"lastUpdatePostDateStruct":350,"startDateStruct":352,"completionDateStruct":353,"leadSponsor":355,"locationsCount":4},"100631819","breathing-and-decision-making-prolex-context-100631819","NCT07505641","Breathing and Decision-Making (ProlEx-Context)","ProlEx-Context","Inclusion Criteria:\n\n* 18- to 40-year-old men and women\n* Consent to participate\n* Fluent in German\n* Right-handed\n* Physically and mentally healthy without regular medication\n* Body-mass index of 18-25 kg\u002Fm2\n* Alcohol consumption of less than 15 glasses a week (equivalent to one glass of wine\u002Fbeer, a glass of higher-percentage alcohol counts as two glasses of beer)\n* No illegal drug consumption in the week previous to the experiment\n* No smoking\n* No competitive athletes\n* Normal day-night rhythm (no shift work)\n* Normal vision without required vision correction (i.e., glasses, contact lenses; ability to clearly read texts at a distance of up to 50 cm without vision aids)\n\nExclusion Criteria:\n\n* Former or current illnesses of:\n* Brain or mind (including anxiety disorders, depression, eating disorders, personality disorders, alcohol, drugs or drug dependence, neurological disorders other than occasional headache, psychiatric or neurological abnormalities)\n* Heart or blood circulation\n* Lung Diseases\n* Other serious past or present medical conditions (for example, metabolic syndrome, diabetes)\n* Current medication and medication over a period of two weeks prior to the examination\n* Other serious health problems or present strong mental or physical stress\n* Current infection or excessive stress\n* Missing consent to receive information about incidental findings from the MRI\n* Tendency to claustrophobia, dizziness, or panic attacks\n* Wearing a non-removable pacemaker, defibrillator, hearing aid, drug pump, neurostimulator or implant with solenoid valve (e.g., artificial bowel outlet)\n* Metal parts or implants inside the body, for example, due to surgery or injury with a metallic foreign object (e.g., hip replacements, artificial joints, heart valves, vessel occlusions or dilatations, surgical clips, bone screws or plates, coil, shunts, catheters, electrodes, coils, radiation sources, shrapnel, projectiles, stents)\n* Having non-removable metal parts or metal-containing devices on or in the body\n* Having ferromagnetic metal parts or implants inside the body (e.g., hip replacements, artificial joints, heart valves, vessel occlusions or dilatations, surgical clips, bone screws or plates, coils, shunts, catheters, electrodes, coils, radiation sources, shrapnel, projectiles, stents)\n* Wearing magnetically fixed implants (e.g. amalgam fillings, glass eye)\n* Professionally or privately being involved in the processing of ferromagnetic metals\n* Large tattoos (whole limbs)\n* Pregnancy\n* Wearing an intra-uterine device\n* Having tinnitus\n* Extensive lung function (e.g. apnoe diver, singer, professional musician with lung-involving instruments)\n* Previous participation in the ProlEx-MRI study (the precursor to the current study)","40 Years",{"count":211,"type":23},[26],"The ProlEx-Context study aims to investigate how a slow-paced breathing technique with prolonged exhalation affects decision-making in the context of acute social stress.",[347,348,217],"Breathing Techniques","Stress Management","2026-03-26",{"date":351,"type":51},"2026-04-01",{"date":351,"type":23},{"date":354,"type":23},"2027-04-01",{"name":356,"class":58},"German Institute of Human Nutrition",{"id":358,"slug":359,"hasResults":11,"nctId":360,"briefTitle":361,"officialTitle":362,"acronym":363,"eligibilityCriteria":364,"healthyVolunteers":11,"sex":18,"minAge":365,"maxAge":365,"enrollmentInfo":366,"targetDuration":4,"studyType":24,"phases":368,"briefSummary":369,"conditions":370,"keywords":371,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":376,"lastUpdatePostDateStruct":377,"startDateStruct":379,"completionDateStruct":381,"leadSponsor":383,"locationsCount":4},"100629799","effects-of-a-tactical-programme-for-critical-thinking-on-football-specific-decision-making-in-under-9-academy-players-100629799","NCT07479368","Effects of a Tactical Programme for Critical Thinking on Football-Specific Decision-Making in Under-9 Academy Players","Effects of a Tactical Programme for Critical Thinking on Football-Specific Decision-Making and Execution Time in Under-9 Academy Players: A Controlled Parallel-Group Study Using the Stroop Task Football Test","TPCT-F-U9","Inclusion Criteria:\n\n* Male academy football players registered in the under-9 category.\n* Regular participation in academy football training.\n* Free from injury at baseline and able to fully participate in training and testing.\n* Written informed consent provided by a parent or legal guardian.\n* Age-appropriate assent provided by the child participant.\n\nExclusion Criteria:\n\n* Any injury or medical condition limiting full participation at baseline.\n* Injury sustained during the study that prevents continued full participation.\n* Absence from more than 25% of intervention sessions.\n* Inability to complete baseline assessment.\n* Inability to complete post-intervention assessment.","9 Years",{"count":367,"type":23},13,[26],"This study evaluates whether embedding a Tactical Programme for Critical Thinking (TPCT) within routine academy football training improves football-specific decision-making and execution speed in under-9 male players. Participants will complete either TPCT-integrated training or standard academy training, and performance will be assessed before and after the intervention using the Stroop Task Football Test (STFT).",[38,33],[372,373,374,375],"Tactical Programme for Critical Thinking","Stroop Task Football Test","Critical Thinking","Execution Time","2026-03-16",{"date":378,"type":51},"2026-03-18",{"date":380,"type":23},"2026-04-14",{"date":382,"type":23},"2026-06",{"name":384,"class":58},"Federal University of Vicosa",{"id":386,"slug":387,"hasResults":11,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":391,"eligibilityCriteria":392,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":4,"enrollmentInfo":393,"targetDuration":4,"studyType":24,"phases":395,"briefSummary":396,"conditions":397,"keywords":400,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":419,"startDateStruct":420,"completionDateStruct":422,"leadSponsor":424,"locationsCount":168},"100581581","data2action-oregon-project-supporting-data-driven-decision-making-for-substance-use-services-policy-and-overdose-prevention-100581581","NCT06852170","Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention","Supporting Data-driven Decision-Making to Support Substance Use Service Expansion Policies and to Prevent Overdoses","D2A Oregon","Inclusion Criteria:\n\nSample 1: Local or Regional Decision Makers\n\n* At least 18 years old\n* Has decision-making authority within their professional role related to substance use service delivery, including leadership responsible for developing policy (e.g. executive directors) OR middle-managers (e.g., case managers, supervisor) and front-line workers responsible for service delivery decisions OR Responsible for developing local or state policy related to substance use\u002Fbehavioral health and\u002For the criminal justice system OR Advises these decision makers (e.g., legislative staff, data analysts)\n\nThese individuals will be drawn from organizations with the following perspectives: behavioral health, public health, health payer, first responders, health advocacy.\n\nSample 2: State or Local Decision Makers\n\n* At least 18 years old\n* Has decision-making authority within their professional role related to substance use service delivery, including leadership responsible for developing policy (e.g. executive directors) OR middle-managers (e.g., case managers, supervisor) and front-line workers responsible for service delivery decisions OR Responsible for developing local or state policy related to substance use\u002Fbehavioral health and\u002For the criminal justice system OR Advises these decision makers (e.g., legislative staff, data analysts)\n\nExclusion Criteria:\n\n* None.",{"count":394,"type":23},341,[26],"Oregon's decision makers (e.g., community service providers, public health, justice, advocacy groups, payers) are calling for comprehensive, current, and trusted data to inform how they allocate resources to improve substance use services and mitigate the growing opioid and methamphetamine epidemics in their state. Consistent with the HEAL Data2Action call for Innovation projects that drive action with data in real-world settings, this study will refine and test the impact of a novel implementation strategy to engage cross- sector decision makers and make data that they identify as relevant to their decisions available to them in easy- to-use products. The proposed study aims to not only address critical knowledge gaps regarding how and when data can inform impactful, transparent decision-making, but to provide decision makers with the data that they need to achieve community-wide substance use prevention and treatment goals, including the increased delivery of high-quality, evidence-informed, services and the prevention of overdoses.",[398,184,187,33,189,399,188],"Substance Abuse","Substance-related Disorders",[401,402,403,398,187,89,404,405,188,184,189,406,407,408,409,410,411,412,413,414,415,416,417],"Health Services Research","Sequential","Stepped Wedge","Substance-related disorders","Substance abuse treatment centers","Focus Groups","Harm Reduction","Policy Making","Law Enforcement","User-Centered Design","Public Health","Opioid-Related Disorders","Naloxone","Methamphetamine","Health Disparate, Minority and Vulnerable Populations","Health Policy","Stakeholder engagement","2026-03-12",{"date":376,"type":51},{"date":421,"type":51},"2025-02-06",{"date":423,"type":23},"2028-08-31",{"name":201,"class":58},{"id":426,"slug":427,"hasResults":11,"nctId":428,"briefTitle":429,"officialTitle":429,"acronym":430,"eligibilityCriteria":431,"healthyVolunteers":17,"sex":112,"minAge":4,"maxAge":4,"enrollmentInfo":432,"targetDuration":4,"studyType":24,"phases":434,"briefSummary":435,"conditions":436,"keywords":437,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":440,"lastUpdatePostDateStruct":441,"startDateStruct":443,"completionDateStruct":445,"leadSponsor":447,"locationsCount":4},"100614321","clinical-decision-making-during-fees-the-impact-of-residue-amount-and-location-100614321","NCT07278076","Clinical Decision-Making During FEES: The Impact of Residue Amount and Location","IRAL","Inclusion Criteria:\n\n* Speech language pathologists with at least one year of experience conducting FEES (flexible endoscopic evaluations of swallowing)\n\nExclusion Criteria:\n\n* Anyone who is not a speech pathologist, or has less than one year of experience conducting FEES.",{"count":433,"type":23},60,[26],"In this study, the investigator aims to identify the threshold of food residue visualized in the throat during a FEES (fiberoptic endoscopic evaluation of swallowing) that speech-language pathologists allow before restricting a patient from eating. 60 speech-language pathologists will be required to participate, with half of them watching a pre-recorded video detailing current research about residue in the throat of pharynx. The group watching the video will then re-score their images. This investigates the impact of education on clinical decision-making. Finally, 8 clinicians will meet with the researcher individually to share their clinical decision-making rationale. With this information, the researcher hopes to identify a patient population who is at risk for diet restrictions in order to encourage speech-language pathologists to extend the swallow study and trial more compensatory strategies before restricting the patient's diet.",[33],[438,439],"clinical decision making","pharyngeal residue severity interpretation","2026-02-19",{"date":442,"type":51},"2026-02-20",{"date":444,"type":23},"2026-11-01",{"date":446,"type":23},"2027-05-30",{"name":448,"class":58},"Rush University Medical Center",{"id":450,"slug":451,"hasResults":11,"nctId":452,"briefTitle":453,"officialTitle":453,"acronym":4,"eligibilityCriteria":454,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":455,"enrollmentInfo":456,"targetDuration":4,"studyType":24,"phases":457,"briefSummary":458,"conditions":459,"keywords":463,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":475,"leadSponsor":477,"locationsCount":168},"100615517","identifying-the-neural-correlates-of-mental-simulation-in-multi-step-planning-100615517","NCT07293637","Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning","Inclusion Criteria:\n\n* N\u002FA\n\nExclusion Criteria:\n\n* History of neurological or psychiatric illness\n* Vulnerable populations","64 Years",{"count":211,"type":23},[26],"Planning is the ability to think ahead by considering possible future actions and their consequences. This research study aims to understand how the brain supports multi-step planning by testing whether people simulate promising future move sequences while deciding what to do next. Healthy adult volunteers will learn and play a strategy game called \"Four-in-a-Row\" (similar to Connect Four). Participants will complete two sessions on successive days: an online behavioral training\u002Fplaying session and an in-person brain-recording session at New York University. During the brain-recording session, participants will view mid-game board positions and choose the best move while the study team records brain activity (using magnetoencephalography \\[MEG\\] or functional MRI \\[fMRI\\]) and eye movements. Data from the game and eye tracking will also be used to fit computational models of planning that help interpret the neural measurements.",[33,136,460,461,462],"Mental Simulation","Problem Solving","Planning",[464,462,465,466,467,468,469],"Four-in-a-Row","Tree search","Computational modeling","Eye tracking","MEG","fMRI","2026-01-07",{"date":472,"type":51},"2026-01-08",{"date":474,"type":51},"2025-07-10",{"date":476,"type":23},"2026-12",{"name":478,"class":58},"New York University",{"id":480,"slug":481,"hasResults":11,"nctId":482,"briefTitle":483,"officialTitle":483,"acronym":484,"eligibilityCriteria":485,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":209,"enrollmentInfo":486,"targetDuration":4,"studyType":488,"phases":4,"briefSummary":489,"conditions":490,"keywords":492,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":497,"lastUpdatePostDateStruct":498,"startDateStruct":499,"completionDateStruct":501,"leadSponsor":503,"locationsCount":168},"100617091","motivation-learning-and-decision-making-in-changing-environments-100617091","NCT07314112","Motivation, Learning and Decision Making in Changing Environments","MOTILEARN","Inclusion Criteria:\n\n* Age between 18 and 45\n* Fluent in French (reading and speaking)\n* Membership or entitlement to a social security plan\n* Have given written, informed consent to take part in the study\n* Normal or corrected-to-normal vision\n* Right-handed\n* Body mass index (BMI) between 18.5 and 30\n\nNon-inclusion Criteria:\n\n* contraindication to MRI: pacemaker, heart battery, cardiac defibrillator, certain heart valves or neurosurgical clips, cochlear implant, implanted automated injection systems (insulin pump), intraocular metal projectiles, people who work or have worked with metals (excluding X-rays prior to MRI).\n* under guardianship or curatorship or deprived of their liberty\n* Participating in a clinical trial or in a period of exclusion from a previous clinical trial\n* Breast-feeding or pregnant women\n* claustrophobia\n* Neurological disorder or severe chronic illness (diabetes, heart, kidney, lung or liver disease, inflammatory disease, psychiatric illness, etc.).\n* The participant does not wish to be informed of any abnormalities detected during the MRI examination.",{"count":487,"type":23},120,"OBSERVATIONAL","The main objective of this study is to develop a models of sequential decision-making, learning and motivation that includes emotions as driving forces of adaptive behaviour. Using functional magnetic resonance imaging (fMRI), the investigators will test the hypotheses that distinct parts of the prefrontal cortex play specific roles in naturalistic decision-making.\n\nThe main hypothesis is that distinct regions of the prefrontal cortex will be differentially involved in learning, motivation, and decision-making in naturalistic tasks. More specifically, the investigators hypothesise that by using a novel set of tasks they have designed in combination with fMRI, they can construct a neurocognitive model that explains how humans make adaptive decisions in dynamic and temporally extended reward environments.\n\nA key region that the investigators believe will play a role in representing the internal and external parameters necessary for adaptive behaviours in the tasks is the anterior cingulate cortex. Depending on the task requirements, this region will further interact with other distinct prefrontal regions such as the frontal pole or dorsolateral prefrontal cortex.\n\nSecondary hypotheses will also be investigated, specific to each specific task.\n\nAll data will be collected during a single visit lasting approximately 3.5 hours for each participant. Participants will perform a cognitive task inside the MRI scanner. Each participant will perform only one of the three possible cognitive conditions\u002Ftasks (Treasure Hunt, Fastest Queue, or Farm Game).\n\nEach task is presented in the form of a video game played on a computer. Participants play a character who makes repeated choices. Participants are asked to try to collect as many points as possible within a limited time frame (Farm Game) or with limited trials (Fastest Queue and Treasure Hunt).",[491,217],"Neurocognitive Model",[493,494,495,496,469],"Cognitive neurosciences","decision making","reward","cognitive psychology","2026-01-05",{"date":470,"type":51},{"date":500,"type":23},"2026-01",{"date":502,"type":23},"2029-01",{"name":504,"class":58},"Hôpital le Vinatier",{"id":506,"slug":507,"hasResults":11,"nctId":508,"briefTitle":509,"officialTitle":510,"acronym":4,"eligibilityCriteria":511,"healthyVolunteers":11,"sex":112,"minAge":19,"maxAge":342,"enrollmentInfo":512,"targetDuration":4,"studyType":24,"phases":513,"briefSummary":514,"conditions":515,"keywords":517,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":520,"startDateStruct":522,"completionDateStruct":524,"leadSponsor":525,"locationsCount":4},"100611027","the-effect-of-digital-games-on-ethical-sensitivity-and-decision-making-in-nursing-students-100611027","NCT07235241","The Effect of Digital Games on Ethical Sensitivity and Decision Making in Nursing Students","The Effect of Digital Game-Based Teaching Methods on the Development of Ethical Sensitivity and Ethical Decision-Making Processes in Nursing Students","Inclusion Criteria:\n\nStudents must:\n\n* Have taken and successfully completed the Nursing Ethics course,\n* Be a fourth-year nursing student who has successfully completed all professional courses and is undertaking the 'Professional Training in the Workplace' placement.\n\nExclusion Criteria:\n\n* Students who have not taken the Nursing Ethics course or have failed the course before taking the Professional Training in the Workplace course.\n* Having a conditional grade point average (CGPA \\\u003C2.00) up to the period when the data was collected.",{"count":433,"type":23},[26],"The study was planned using a randomised controlled experimental design to determine the effectiveness of digital game-based teaching in the development of ethical sensitivity and ethical decision-making processes among nursing students.",[33,516],"Ethics",[516,33,518,316],"Digital Game","2025-11-17",{"date":521,"type":51},"2025-11-19",{"date":523,"type":23},"2026-03",{"date":382,"type":23},{"name":526,"class":58},"Istanbul Medeniyet University",{"id":528,"slug":529,"hasResults":11,"nctId":530,"briefTitle":531,"officialTitle":532,"acronym":4,"eligibilityCriteria":533,"healthyVolunteers":17,"sex":112,"minAge":4,"maxAge":4,"enrollmentInfo":534,"targetDuration":4,"studyType":24,"phases":535,"briefSummary":536,"conditions":537,"keywords":543,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":553,"startDateStruct":554,"completionDateStruct":556,"leadSponsor":558,"locationsCount":4},"100611065","the-effect-of-laughter-yoga-on-individual-and-organizational-outcomes-in-nurse-managers-100611065","NCT07235735","The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers","The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers: A Longitudinal Study","Inclusion Criteria:\n\n* Currently working as a nurse manager\n* Having at least six months of managerial experience\n* Continuing to serve as a nurse manager throughout the study period\n\nExclusion Criteria:\n\n* Having previously received laughter yoga training\n* Use of medications affecting general health components during the study (e.g., for depression, anxiety)\n* Being pregnant\n* Experiencing an acute stressful life event, such as the death of a close relative\n* Having undergone abdominal surgery within the past 6 months",{"count":178,"type":23},[26],"The goal of this clinical trial is to learn if laughter yoga can improve both individual and organizational outcomes in nurse managers. The main questions it aims to answer are:\n\n* Does laughter yoga lower burnout and stress levels in nurse managers?\n* Does laughter yoga improve work-life quality and job performance?\n* Does laughter yoga help nurse managers make better decisions and solve problems more effectively?\n* Does laughter yoga lower compassion fatigue and support positive approaches to workplace conflict? Researchers will compare a laughter yoga group with a control group to see if there are meaningful differences.\n\nParticipants will:\n\n* Join structured laughter yoga sessions for a defined period (weekly sessions).\n* Complete surveys before and after the program about stress, burnout, work-life quality, decision-making, problem solving, job performance, compassion fatigue, and conflict approaches.\n* Continue their usual work while attending sessions.",[538,539,540,541,33,461,542],"Burnout, Professional","Stress, Psychological","Compassion Fatigue","Quality of Life","Work Performance",[544,545,546,547,548,33,461,549,540,550,551,552],"Nurse Managers","Laughter Yoga","Burnout","Stress","Work-Life Balance","Job Performance","Conflict Management","Organizational Outcomes","Professional Development",{"date":521,"type":51},{"date":555,"type":23},"2025-12-11",{"date":557,"type":23},"2026-03-17",{"name":559,"class":58},"Zonguldak Bulent Ecevit University",{"id":561,"slug":562,"hasResults":11,"nctId":563,"briefTitle":564,"officialTitle":565,"acronym":566,"eligibilityCriteria":567,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":342,"enrollmentInfo":568,"targetDuration":4,"studyType":24,"phases":569,"briefSummary":570,"conditions":571,"keywords":573,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":578,"lastUpdatePostDateStruct":579,"startDateStruct":581,"completionDateStruct":583,"leadSponsor":585,"locationsCount":168},"100353756","combined-anodal-transcranial-direct-current-stimulation-tdcs-and-cognitive-training-and-decision-making-100353756","NCT03886025","Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training and Decision-making","The Use of Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training to Modulate Decision-making in Healthy People","tDCS-CTDM","Inclusion Criteria:\n\n* Consenting volunteers aged between 18 and 40.\n\nExclusion Criteria:\n\n* Individuals with epilepsy, other neurological conditions and history of significant head injury will be excluded.\n* Individuals with a history of substance misuse, major mental disorder and those receiving psychotropic medication will be also excluded.",{"count":433,"type":23},[26],"This study aims to (i) assess the effects of combined tDCS and cognitive training on decision-making on a trained task (Iowa Gambling Task; IGT); and (ii) test generalization to a closely related cognitive domain, namely motor impulsivity. It is hypothesized that combined anodal tDCS and cognitive training will result in more advantageous decisions and better impulse control than combined sham tDCS and cognitive training.",[572,33],"Impulsivity",[574,575,576,577],"transcranial Direct Current Stimulation (tDCS)","Decision-making","Implusivity","Brain stimulation","2025-08-04",{"date":580,"type":51},"2025-08-08",{"date":582,"type":51},"2022-09-15",{"date":584,"type":23},"2026-12-30",{"name":586,"class":58},"Dr. Najat Khalifa",{"id":588,"slug":589,"hasResults":11,"nctId":590,"briefTitle":591,"officialTitle":592,"acronym":4,"eligibilityCriteria":593,"healthyVolunteers":17,"sex":112,"minAge":19,"maxAge":594,"enrollmentInfo":595,"targetDuration":596,"studyType":488,"phases":4,"briefSummary":597,"conditions":598,"keywords":604,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":608,"lastUpdatePostDateStruct":609,"startDateStruct":611,"completionDateStruct":613,"leadSponsor":615,"locationsCount":4},"100591815","3-dimensional-evaluation-of-body-perception-100591815","NCT06985329","3-Dimensional Evaluation of Body Perception","Evaluation of Neurocognitive Skills, VisuoSpatial Perception and Perspective Perception in Amputees","Inclusion criteria for the amputee group:\n\n* Acquired amputees\n* Aged 18-65 years\n* Using a prosthesis for at least six months\n* At least a primary school graduate\n* Individuals who can adapt to prolonged, attention-demanding activities will be included.\n* Standardised Mini Mental State Examination score of \\>24.\n\nFollowing the recruitment of the amputee group, a healthy control group will be recruited to match it in terms of age, gender and educational status.\n\nInclusion criteria for the healthy control group:\n\n* Age range: 18-65 years\n* At least a primary school graduate\n* Individuals who can adapt to prolonged, attention-demanding activities will be included.\n* Standardised Mini Mental State Examination score of \\>24.\n\nExclusion criteria for the amputee group:\n\n* Individuals with congenital amputation\n* Those with phantom limb pain and\u002For sensation\n* Those with an open wound on the stump\n* Bilateral amputation\n* Any neurological or psychiatric diagnosis\n* Those using sedative medication and\u002For its derivatives\n* Have vision and related problems\n* Individuals who are illiterate\n* Individuals participating in treatments targeting body representation (e.g. imagery-based treatments or progressive motor visualisation) will not be included in the study.\n\nExclusion criteria for the Healthy Control Group:\n\n* Having any neurological or psychiatric diagnosis\n* Using sedative medication and\u002For its derivatives\n* People with vision and related problems\n* Illiterate individuals will not be included in the study.","65 Years",{"count":433,"type":23},"15 Days","The goal of this observational study is to evaluate the changing body perception of amputees aged 18-65 years using prostheses through different personal perspectives of the right-left distinction. In addition, we aimed to examine the relationship between possible changes in body perception and visual spatial perception and neurocognitive performances. The main questions that this study aimed to answer are as follows:\n\n1. Is there a difference between the amputee group and the control group in terms of parameters related to body perception?\n2. Is there a difference between the amputee group and the control group in terms of neurocognitive skills?\n3. Is there any difference between the amputee group and the control group in terms of visual spatial perception abilities?\n\nTo examine whether changes in body perception in amputees affect neurocognitive performance, visuospatial perception and perspective perception and the relationship between them will be compared with a healthy control group.\n\nThe assessments to be applied to both groups can be summarised as follows:\n\n* Demographic information such as age, gender, and education level will be recorded.\n* Mini-mental state test will be used to assess the cognitive level.\n* Edinburgh Handedness Scale will be used to determine the dominant side.\n* Right-left discrimination and personal perspective perception will be assessed using a desktop programme.\n* The clock drawing test and Benton line orientation test will be used to visual spatial perception.\n* A computer based program called The Central Nervous System (CNS) Vital Signs Neurocognitive Test Battery will be used to asesses neurocognitive abilities.",[599,136,33,600,601,602,603],"Body Image","Visuospatial\u002FPerceptual Abilities","Neurocognitive Function","Executive Function (Cognition)","Amputation",[599,136,605,603,606,33,607],"Neuropsychological Test","Executive Function","Visuospatial Skills","2025-05-14",{"date":610,"type":51},"2025-05-22",{"date":612,"type":23},"2025-06",{"date":614,"type":23},"2026-06-15",{"name":616,"class":58},"Trakya University",{"id":618,"slug":619,"hasResults":11,"nctId":620,"briefTitle":621,"officialTitle":621,"acronym":622,"eligibilityCriteria":623,"healthyVolunteers":11,"sex":112,"minAge":19,"maxAge":4,"enrollmentInfo":624,"targetDuration":4,"studyType":488,"phases":4,"briefSummary":626,"conditions":627,"keywords":630,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":633,"lastUpdatePostDateStruct":634,"startDateStruct":635,"completionDateStruct":636,"leadSponsor":637,"locationsCount":4},"100590791","peri-operative-surgical-care-optimisation-for-patients-requiring-emergency-surgery-100590791","NCT06972017","Peri-Operative Surgical Care Optimisation for Patients Requiring Emergency Surgery","PERI-SCOPES","Group 1 and 2: EmLap and NoLap patients (up to 30 participants)\n\nPatient inclusion\u002Fexclusion criteria should mirror NELA inclusion\u002Fexclusion criteria and NELA NoLap guidelines. NELA is the \"National Emergency Laparotomy Audit\" which recruits patients in Wales and England and there inclusion\u002Fexclusion criteria are widely accepted for use in Emergency General Surgery research.\n\nInclusion criteria\n\n* Age \\>65 years old\n* Able to communicate in English\n* Cognitively able to complete the survey\u002Finterviews\n* Able to provide informed, voluntary consent\n* First line treatment is expedited, urgent or emergency abdominal surgery on the gastrointestinal tract\n* Surgery can be laparoscopic or open approach\n\nExclusion criteria\n\n* Age \\\u003C65 years old\n* NoLaps should be excluded if management involved interventional radiology or endoscopic procedures\n* Patients who are offered a period of conservative treatment are not automatically NoLap if surgery may ultimately be offered\n* Diagnosis of dementia or long-standing cognitive impairment\n* Elective laparotomy\u002Flaparoscopy\n* Diagnostic laparotomy\u002Flaparoscopy where no subsequent procedure is performed (however, if no procedure is performed because of inoperable pathology, then include)\n* All surgery involving the appendix or gallbladder, including any surgery relating to complications\n* Non-elective hernia repair without bowel resection or division of adhesions\n* Non-elective formation of colostomy or ileostomy\n* Trauma surgery (blunt or penetrating), vascular surgery, obstetric\u002Fgynaecological surgery or transplant surgery\n* Surgery for pathology of oesophagus, spleen, renal tract, kidneys, liver, gallbladder and biliary tree, pancreas or urinary tract\n\nGroup 3: Families\u002FSupporters (up to 30 participants) Inclusion criteria\n\n* Identified by the patient participant (only approached if nominated by patient)\n* Age \\>18 years old\n* Able to communicate in English\n* Cognitively able to complete the survey\u002Finterviews\n* Able to provide informed, voluntary consent\n\nExclusion criteria\n\n* Age\\\u003C18 years old\n* Lack of patient consent to family\u002Fsupporter involvement\n\nGroup 3: Consultants (interview:12-20 participants\u002Fsurvey: minimum 52 participants) Inclusion criteria\n\n* Key decision-makers will be identified in workstream 1 (likely: surgeons, intensivists and anaesthetists)\n* Post-CCT (Certificate of Completion of Training)\n* Participate in active on-call for EGS in a UK-based Hospital where they make decisions in EGS regularly\n\nExclusion criteria\n\n• Consultants not done \\>2 years of on-call",{"count":625,"type":23},112,"Emergency General Surgery (EGS) is an umbrella term which describes all patients presenting to hospital with an acute abdominal problem. Patients can have various conditions requiring emergency operations. EGS is one of the most common reasons for an emergency admission in the UK.\n\nEGS is often referred to as \"high-risk\" surgery. For those patients who do survive after their surgery, many struggle with frailty and new medical problems resulting in a reduction in their quality of life (QoL).\n\nThe goal of this observational study is to explore QoL and decision-making in EGS through questionnaires and interviews with patients, families\u002Fsupporters and consultants working in EGS.\n\nWorkstream 1 will involve patients and families\u002Fsupporters. Workstream 2 will involve consultants.\n\nThe investigators are interested in patients who have either undergone EGS (EmLaps) or have needed but not undergone EGS (NoLaps). The investigators are interested in exploring participants (patients, families\u002Fsupporters and consultants) experiences of this EmLap vs NoLap decision.\n\nThe main questions the investigators want to answer are:\n\n* What is the long-term QOL of EmLap\u002FNoLap patients and their family\u002Fsupporters?\n* How do patients and their family\u002Fsupporters describe their experience of decision-making in EGS?\n* What are consultant's experiences and views on decision-making in EGS?\n\nWorkstream 1 participants (patients and family members\u002Fsupporters) will complete questionnaires and take part in interviews at different time-points following their decision (1 month\u002F3 months\u002F 9-12 months). Questionnaires and interviews will explore QoL and decision-making in EGS.\n\nConsultant participants will be asked to complete an online survey and\u002For take part in an individual interview. Both will explore decision-making in EGS.",[628,33,629],"Quality of Life (QOL)","Emergency General Surgery",[541,575,631,632,629],"NoLap","EmLap","2025-05-06",{"date":608,"type":51},{"date":612,"type":23},{"date":255,"type":23},{"name":638,"class":58},"NHS Greater Glasgow and Clyde",{"id":640,"slug":641,"hasResults":11,"nctId":642,"briefTitle":643,"officialTitle":644,"acronym":645,"eligibilityCriteria":646,"healthyVolunteers":11,"sex":112,"minAge":594,"maxAge":4,"enrollmentInfo":647,"targetDuration":4,"studyType":24,"phases":649,"briefSummary":650,"conditions":651,"keywords":658,"overallStatus":158,"whyStopped":4,"lastUpdateSubmitDate":665,"lastUpdatePostDateStruct":666,"startDateStruct":668,"completionDateStruct":670,"leadSponsor":672,"locationsCount":674},"100572291","improved-prescribing-for-older-nursing-home-patients-100572291","NCT06731361","Improved Prescribing for Older Nursing Home Patients","Improving Medication Prescription in the contExt of Advance Care Planning for paTients Receiving Long Term nUrSing Home Care","IMPETUS","Inclusion Criteria:\n\nNursing home patients:\n\n* Age 65years and above\n* Living at long term care wards in nursing homes\n* Living at a long term care ward for at least 4 weeks before start of the study\n\nExclusion Criteria:\n\n* Temporary nursing home patients (i.e. geriatric rehabilitation or end-of-life\u002Fhospice care)\n* Life expectancy \\\u003C 4 weeks\n* Life expectancy clearly \\> 1.5 - 2 years (i.e. patients with Huntingtons disease)",{"count":648,"type":23},450,[26],"Research aim:\n\nTo investigate the effect of training health care professionals in medication assessments on the medication use of nursing home residents with a limited life expectancy (\\\u003C 1.5-2 years).\n\nThe core of the training is to tailor medication use to (palliative) treatment goals of nursing home residents.\n\nDesign:\n\nA cluster randomized controlled trial on long term care wards in nursing homes, with the nursing home care organisations as unit of randomisation. The investigators intent to include 6 organisations and 450 nursing home patients. The research starts in september and lasts 1 year and 3 months. Eligible patients are nursing home patients of 65 years and older with a limited life expectancy (\\\u003C 1.5-2 year) of long term care wards.\n\nIntervention:\n\nThe intervention includes a method in which healthcare professionals (medical practitioner, pharmacist and care worker) are trained to tailor medication to the (palliative) treatment goals of nursing home patients with a limited life expectancy. The training consists of 2 components: 1) medication assessment, and 2) advance care planning (ACP). In the intervention group, healthcare professionals receive the training in combination with supporting tools and educational materials, in the control group care continues as normal. The allocation ratio for control and intervention groups is 1:1. A process evaluation will take place simultaneously with the intervention study. Data collection takes place before the start of the intervention (T0), after 6 months (T1) and after 12 months (T2).\n\nOutcome measures:\n\nThe primary outcome measure is potential under- and over-treatment with medication. The secondary outcome measure is experienced involvement in decision-making (measured with a short questionnaire based on the revised PATD (patients' attitude towards deprescribing)). Tertiary outcome measures are: quality of life, deaths, falls, hospital admissions\u002Facute first aid referrals and pain.\n\nDiscussion:\n\nThe intervention is expected to result in a decrease in chronic and preventive medication prescriptions, an increase in medication for symptom treatment and more involvement (and satisfaction) of the nursing home resident in decision-making, without adverse effects.",[652,653,654,655,656,33,657],"Nursing Home Residents","Older People","Prescribing","Advance Care Planning","Medication Reviews","Prescribing Practices",[659,660,661,662,663,92,664],"limited life expectancy","ReNeWAL criteria (adjusted STOPP\u002FSTART criteria)","decision making involvement","appropriate prescribing","Cluster randomised trial","Prescribing practices","2024-12-09",{"date":667,"type":51},"2024-12-12",{"date":669,"type":51},"2024-09-10",{"date":671,"type":23},"2025-12-01",{"name":673,"class":58},"Amsterdam UMC, location VUmc",7,{"id":676,"slug":677,"hasResults":11,"nctId":678,"briefTitle":679,"officialTitle":680,"acronym":4,"eligibilityCriteria":681,"healthyVolunteers":17,"sex":66,"minAge":682,"maxAge":683,"enrollmentInfo":684,"targetDuration":4,"studyType":24,"phases":686,"briefSummary":687,"conditions":688,"keywords":691,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":693,"lastUpdatePostDateStruct":694,"startDateStruct":696,"completionDateStruct":698,"leadSponsor":699,"locationsCount":4},"100522378","strengthening-contraceptive-counseling-services-research-protocol-for-a-multi-phase-complex-intervention-in-pakistan-and-nigeria-100522378","NCT06081842","Strengthening Contraceptive Counseling Services: Research Protocol for a Multi-phase Complex Intervention in Pakistan and Nigeria","Strengthening Contraceptive Counseling Services, a Multi-country Study Trial","Inclusion Criteria:\n\n1. Client comes to the family planning clinic with the intention to 1.a. use contraception for the first time in her life (new user), or 1.b. switch from a contraceptive method to another one (switching user), or 1.c. resume a method after not using any in the prior three months (lapse user), or 1.d. discontinue a modern method (discontinuing user);\n2. Client is not coming for the resupply of a currently used method, such as pills or injectables;\n3. Client has the intention to continue her follow-up at the health center during the duration of study follow-up;\n4. Client does not participate in another study; and\n5. Client provides informed consent.\n\nExclusion Criteria:\n\nNot willing to participate in the complete duration of the trial","15 Years","49 Years",{"count":685,"type":23},7920,[26],"High-quality contraceptive counseling can strengthen global efforts to reduce the unmet need for and suboptimal use of modern contraceptives. This study aims to identify a package of contraceptive counseling interventions for Pakistan and Nigeria designed to strengthen existing contraceptive services and determine its effectiveness in increasing clients' level of decision-making autonomy and meeting their contraceptive needs.",[689,690,33],"Contraception","Empowerment",[692],"Family Planning, Counselling, choice","2023-10-07",{"date":695,"type":51},"2023-10-13",{"date":697,"type":23},"2023-11",{"date":382,"type":23},{"name":700,"class":58},"World Health Organization"]