[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"decompressive-craniectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:decompressive-craniectomy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100380159","prospective-observational-real-world-treatments-of-aedh-in-large-scale-surgical-cases-100380159",false,"NCT04229966","Prospective, Observational Real-world Treatments of AEDH in Large-scale Surgical Cases","A Real World, Multicenter, Prospective, Observational Study to Compare Effectiveness of Surgical Treatments in Patients With Acute Epidural Hematoma","PORTALS-AEDH","Inclusion Criteria:\n\n1. Clear medical history of traumatic brain injury;\n2. within 12 hours after injury;\n3. Supratentorial unilateral acute epidural hematoma on first head CT scan examination;\n4. The admitting neurosurgeon considers that the epidural hematoma needs to be evacuated with surgical treatment;\n5. With informed consent to surgery and trial participation.\n\nExclusion Criteria:\n\n1. Previous intracranial surgery prior to trauma;\n2. Patients with a score of 3 on the GCS, with bilateral fixed and dilated pupils, bleeding diathesis or defective coagulation, or an injury that was deemed to be unsurvivable;\n3. CT demonstrates associated other intracranial hematomas e.g. subdural, intracerebral hemorrhage, or large size infarction, which are the main causes of operation;\n4. Patients who had injury of the oculomotor nerve;\n5. Severe pre-existing disability or severe co-morbidity which would lead to a poor outcome even if the patient is supposed to a good recovery from the TBI;\n6. Pregnant female.","ALL","18 Years","65 Years",{"count":21,"type":22},2000,"ESTIMATED","6 Months","OBSERVATIONAL","This is a multicenter, prospective, and observational real-world study aimed at investigating the current situation of surgical treatments and prognosis for acute epidural hematoma in China, and analyzing the optimization of therapy.",[27,28,29],"Epidural Hematoma","Decompressive Craniectomy","Craniotomy","RECRUITING","2026-01-12",{"date":33,"type":34},"2026-01-14","ACTUAL",{"date":36,"type":34},"2020-11-02",{"date":38,"type":22},"2027-12-31",{"name":40,"class":41},"RenJi Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":66,"locationsCount":42},"100546151","study-on-the-efficacy-of-long-term-drainage-of-subdural-effusion-after-decompressive-craniectomy-100546151","NCT06391203","Study on the Efficacy of Long-term Drainage of Subdural Effusion After Decompressive Craniectomy","A Randomised Controlled Trial to Evaluate Long-term Drainage for Patients Undergoing Decompressive Craniectomy With the Complication of Subdural Diffusion","Inclusion Criteria:\n\n1. Unilateral DC surgery was performed on TBI patients after injury;\n2. Subdural effusion occurred for the first time and occurred within 30 days after DC surgery;\n3. Unilateral effusion accumulation (can appear on the same or opposite side of the bone flap);\n4. The subdural effusion cannot be absorbed or has no decreasing trend with conservative treatment and consistent with the indications for surgical treatment;\n5. Sign the study informed consent;\n\nExclusion Criteria:\n\n1. History of craniocerebral disease or craniocerebral surgery;\n2. Patients with intracranial infection (cerebrospinal fluid test results must be confirmed by lumbar puncture before inclusion);\n3. Combined with ventricular hydrocephalus;\n4. Other factors lead to poor prognosis or affect the treatment plan of the patient, even if the effusion can be recovered well, but severe pre-existing disability or severe co-morbidity such as serious heart disease leads to poor prognosis or even death;\n5. Pregnant female.",{"count":51,"type":22},160,"INTERVENTIONAL",[54],"NA","Drilling or puncture drainage is commonly used in TBI patients with subdural effusion following decompressive craniectomy who fail to respond to conservative treatment, but there is no exact regulation or guideline recommendation for the drainage time. The investigators aimed to conduct a randomized controlled trial to evaluate the efficacy and safety of long-term versus short-term drainage in the treatment of subdural effusion after decompressive craniectomy in patients with traumatic brain injury.",[57,28,58],"Traumatic Brain Injury","Subdural Effusion","NOT_YET_RECRUITING","2024-05-02",{"date":62,"type":34},"2024-05-06",{"date":64,"type":22},"2024-06-01",{"date":38,"type":22},{"name":40,"class":41}]