[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"deep-brain-stimulation-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:deep-brain-stimulation-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100607375","effect-of-mediterranean-diet-on-nutrition-in-parkinsons-disease-patients-with-bilateral-subthalamic-deep-brain-stimulation-100607375",false,"NCT07187739","Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation","Investigation of the Effect of the Mediterranean Diet on Nutritional Status in Parkinson's Patients Undergoing Bilateral Subthalamic Nucleus Deep Brain Stimulation","Inclusion Criteria:\n\n* Being between 45-64 years of age\n* Signing informed consent\n* Undergoing STN DBS surgery\n* Continuing antiparkinsonian therapy\n* Those with a Mini Mental Test result of ≥24 points\n\nExclusion Criteria:\n\n* Having any psychiatric illness\n* Those with a Mini Mental Test result of \\\u003C24 points\n* Those with a disease requiring a special diet other than Parkinson's Disease","ALL","45 Years","64 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate whether Mediterranean diet can help manage body weight and improve body composition in adult Parkinson's disease patients who have undergone bilateral subthalamic nucleus deep brain stimulation (STN DBS).\n\nThe main questions it aims to answer are:\n\nDoes adherence to the Mediterranean diet for three months post-surgery help control body weight gain in STN DBS patients?\n\nDoes the Mediterranean diet positively affect body composition and other clinical parameters such as nutritional status, appetite, quality of life, and physical activity?\n\nResearchers will compare an intervention group following the Mediterranean diet with a control group continuing their usual diet to see if dietary guidance leads to improvements in weight management, body composition, and other nutritional status parameters.\n\nParticipants will:\n\nBe randomized into intervention and control groups.\n\nReceive Mediterranean dietary recommendations (intervention group) or continue usual diet (control group).\n\nUndergo evaluations at baseline (pre-operative), and at the 1st, 2nd, and 3rd months post-operatively using the following tools:\n\nVisual Appetite Scale\n\nHoehn and Yahr Questionnaire\n\nParkinson's Disease Quality of Life Questionnaire-8\n\nMovement Disorder Society-Unified Parkinson's Disease Rating Scale - Part 2\n\nMediterranean Diet Adherence Scale\n\nFood Consumption Record\n\nHave their anthropometric measurements and body composition (e.g., weight, waist and neck circumference, upper arm circumference, handgrip strength) assessed.",[27,28,29],"Parkinson Disease","Deep Brain Stimulation","Deep Brain Stimulation Surgery",[31,32,33,34,27],"Mediterranean Diet","Body Weight","Body Composition","Dietary Assesment","RECRUITING","2025-11-26",{"date":38,"type":39},"2025-12-03","ACTUAL",{"date":41,"type":39},"2025-09-25",{"date":43,"type":21},"2026-03",{"name":45,"class":46},"Ankara University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100546894","analysis-of-deep-brain-nuclei-lfp-and-cortical-eeg-signals-during-the-recovery-from-general-anesthesia-100546894","NCT06400901","Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia","Electrophysiology Based Brain Network Study on Deep Brain Nuclei LFP and Cortical EEG During the Recovery From General Anesthesia","Inclusion Criteria:\n\n* 18-75 years old\n* ASA (American Society of Anesthesiologists) classification I-III\n* Those who meet the indications for DBS surgery\n* Right-handed with normal listening and speaking abilities\n* The patient signs the informed consent form and cooperates with the researchers\n\nExclusion Criteria:\n\n* Patients with cognitive impairment \\[Montreal Cognitive Assessment (MoCA) score less than 26 points\\];\n* Patients with severe depression \\[Beck Depression Inventory (BDI-II) score greater than or equal to 25 points\\];\n* Patients with important organs dysfunction, such as heart, lungs, liver, and kidneys; or patients with unstable vital signs;\n* Patients who are expected to enter the ICU after surgery;\n* Patients who are alcoholic, alcohol dependent or drug dependent;\n* Patients who have received general anesthesia one month before surgery, patients who are known to be allergic to general anesthetics;\n* The DBS surgery exceeds 4 hours;\n* Patients who are pregnant.","18 Years","75 Years",{"count":58,"type":21},42,"OBSERVATIONAL","The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp electroencephalogram (EEG) of the frontal cortex were recorded from patients undergoing deep brain stimulation (DBS) surgery during the recovery from general anesthesia, in order to explore the changes and relevance of deep brain nuclei firing and cortex activity during the recovery of consciousness from general anesthesia .",[29,62,63,64],"Electrophysiology","General Anesthesia","Consciousness, Loss of",[66,67,68,69],"cortex EEG","deep brain nuclei","local field potentiation","propofol","2024-05-09",{"date":72,"type":39},"2024-05-13",{"date":74,"type":21},"2024-05-15",{"date":76,"type":21},"2026-10-15",{"name":78,"class":46},"Ruijin Hospital"]