[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"deformity-of-limb\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:deformity-of-limb":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100555983","study-of-infantile-lower-limb-malformations-and-deformities-100555983",false,"NCT06519175","Study of Infantile Lower Limb Malformations and Deformities","Observational Retrospective and Prospective Study of Infantile Lower Limb Malformations and Deformities","REMEDIA-I","Inclusion Criteria:\n\n* Age \\\u003C 18 years at the time of initial orthopedic evaluation\n* Diagnosis of congenital or acquired musculoskeletal deformity to one or both lower limbs\n* Presence of informed consent to participate in the study\n\nExclusion Criteria:\n\n* Refuse to participate in the study by the patient or parent\u002Flegal guardian\n* Patients with mild paramorphisms not associated with functional limitations","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure. These alterations can be symmetrical or asymmetrical, with potential consequences such as deformities, short stature, and disability. These condictions may impact not only on the physical and the mental function of the children, but also on their family context.\n\nManagement often requires a multidisciplinary approach for early diagnosis and treatment. Deformities are heterogeneous and necessitate a personalized therapeutic plan.\n\nCurrently, in pediatric orthopedic surgery there is a lack of an instrument capable of evaluating all these aspects.\n\nThe advancement of computer-assisted surgery and artificial intelligence could improve treatment customization and involve patients and families in therapeutic decision-making to prevent complications. This study aims to provide support for clinical practice to promote a systematic, comprehensive, and sequential evaluation of lower limb deformities in developmental age, from which epidemiological data and evidence on treatment approaches used in major referral centers can be extrapolated.",[25],"Deformity of Limb",[27,28,29],"Pediatric orthopedics","Deformity","Patient Reported Outcomes","RECRUITING","2025-12-19",{"date":33,"type":34},"2025-12-26","ACTUAL",{"date":36,"type":34},"2024-10-31",{"date":38,"type":21},"2029-05",{"name":40,"class":41},"Istituto Ortopedico Rizzoli","OTHER",7,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":56,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100467071","pediatric-orthopaedic-implant-safety--efficacy-100467071","NCT05361980","Pediatric Orthopaedic Implant Safety & Efficacy","Global Pediatric Orthopaedic Implant Safety & Efficacy Clinical Follow-up Program","Global POISE","Inclusion Criteria:\n\n* Patients indicated for the device-specific indication, per physician discretion and as indicated in the device IFU. Off-label use is strongly discouraged; however, any and all on- and off-label indications for use of the products in this program will be collected and stratified accordingly\n* Patients must be able to adhere to the required length of follow-up for the endpoints of each individual product\n* Informed consent\u002Fassent is required\n\nExclusion Criteria:\n\n* Patients with a demonstrated sensitivity to metals\n* Patients with an inability to follow a post-operative regimen",true,"0 Years","25 Years",{"count":55,"type":21},4000,"2 Years","Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.\n\nGiven the vital role fixation devices play in maintaining alignment, promoting healthy bone healing and preventing joint degeneration, it is essential to understand the expected lifetime outcomes of these implants, and evaluate their safety and efficacy.\n\nProspective implant efficacy and safety registries are needed to support this endeavour, especially considering new regulatory requirements from the European Union Medical Devices Regulation (EU MDR) in relation to post-market clinical follow-up (PMCF).",[59,60,61,25,62,63,64,65,66,67,68],"Fracture","Lengthening; Leg","Orthopedic Disorder","Deformity; Bone","Implant Breakage","Implant Complication","Hip Dysplasia","Pediatric ALL","Hip Disease","Hip Dislocation","2025-11-19",{"date":71,"type":34},"2025-11-24",{"date":73,"type":34},"2022-01-06",{"date":75,"type":21},"2029-12",{"name":77,"class":41},"University of British Columbia",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":90,"studyType":22,"phases":4,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":78},"100380586","rsa-study-on-the-behaviour-of-the-growth-plate-during-and-after-temporary-hemi-epiphysiodesis-and-epiphysiodesis-100380586","NCT04235517","RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis","Behaviour of the Growth Plate in Patients Operated With Either Permanent or Temporary Hemi-epiphysiodesis or Epiphysiodesis Through by the Use of Radiostereometric Analysis (RSA)","Inclusion Criteria:\n\n* Children with idiopathic axial deviations in the lower extremities\n* Children with limb length discrepancys where timing of epiphysiodesis is difficult because of a big discrepancy in skeletal age and chronological age\n\nExclusion Criteria:\n\n* Children with axial deviations and pathological physis","3 Years","16 Years",{"count":89,"type":21},10,"5 Years","By using radiostereometric analysis (RSA) we will be able to study growth during and after temporary epiphysiodesis and with great accuracy be able to detect asymmetric growth following this procedure.\n\nBy using the same method we also want to analyse patients with axial deviations operated with guided growth (tension band plating) to study the growth during and after the procedure and be able to set the correct timing for removal of the implant.",[93,25],"Anisomelia",[95],"LLD, guided growth","2025-09-03",{"date":98,"type":34},"2025-09-04",{"date":100,"type":34},"2017-01",{"date":102,"type":21},"2027-01",{"name":104,"class":41},"Oslo University Hospital"]