[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"degenerative-arthritis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:degenerative-arthritis":35},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,61,85,117],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":60},"100245148","clinical-outcomes-study-of-the-nexel-total-elbow-100245148",false,"NCT02469662","Clinical Outcomes Study of the Nexel Total Elbow","Retrospective and Prospective Clinical Outcomes Study of the Zimmer® Nexel™ Total Elbow","Inclusion Criteria:\n\n* Patient is 18 years of age or older.\n* Patient must have signed Institutional Review Board (IRB)\u002FEthics Committee (EC)-approved informed consent.\n* Patient is a candidate for primary or revision total elbow arthroplasty, based on symptoms including at least one of the following:\n\n  * Elbow joint destruction which significantly compromises daily living activities\n  * Post-traumatic lesions or bone loss contributing to elbow instability\n  * Ankylosed joints, especially cases of bilateral ankylosis from causes other than active sepsis\n  * Advanced rheumatoid arthritis, post-traumatic, or degenerative arthritis with incapacitating pain\n  * Instability or loss of motion when the degree of joint or soft tissue damage precludes reliable osteosynthesis\n  * Acute comminuted articular fracture of elbow joint surfaces that precludes less radical procedures, including 13-C3 fractures of the distal humerus\n* Patient is willing and able to complete scheduled follow-up evaluations as defined by the protocol.\n\nAdditional Retrospective Arm Inclusion Criteria\n\n* Patient must have undergone a total elbow replacement with the Nexel system between July 2013 and the date of the site initiation visit.\n* Patient information available for each retrospective patient must, at minimum, include preoperative demographic information, preoperative physical exam information, the index surgery operative report, and details of the devices implanted.\n\nExclusion Criteria:\n\n* Patient has a currently active or history of repeated local infection at the surgical site.\n* Patient has a current major infection distant from the operative site.\n* Patient has a history of prior sepsis.\n* Patient suffers from paralysis or dysfunctional neuropathy at the elbow joint.\n* Patient has significant ipsilateral hand dysfunction.\n* Patient has excessive scarring near the surgical site, which could prevent adequate soft tissue coverage.\n* Patient participates in daily activities that may cause significant stress to an implanted device such as heavy labor, torsional stress, and\u002For competitive sports.\n* Patient is a prisoner.\n* Patient is mentally incompetent or unable to understand what participation in the study entails.\n* Patient is a known alcohol or drug abuser.\n* Patient is anticipated to be non-compliant.\n* Patient is known to be pregnant.","ALL","18 Years",{"count":19,"type":20},134,"ESTIMATED","INTERVENTIONAL",[23],"NA","The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.",[26,27,28,29,30,31,32,33,34,35],"Elbow Joint Destruction","Post-traumatic Lesions","Ankylosed Joints","Advanced Rheumatoid Arthritis","Joint Instability or Loss of Motion","Acute Comminuted Articular Fracture of Elbow Joint Surfaces","Bone Loss Contributing to Elbow Instability","Bilateral Ankylosis From Causes Other Than Active Sepsis","Post-traumatic Arthritis","Degenerative Arthritis",[37,38,39,40,29,41,35,26,42,28,43,44,45,46,47],"Total Elbow Arthroplasty","TEA","Elbow Arthroplasty","Elbow Replacement","Post-Traumatic Arthritis","Post-Traumatic Lesions or Bone Loss","Acute Comminuted Articular Fracture","Significantly compromises daily living activities","Joint or soft tissue damage","Precludes less radical procedures","13-C3 fractures of the distal humerus","RECRUITING","2025-10-28",{"date":51,"type":52},"2025-10-29","ACTUAL",{"date":54,"type":52},"2015-06",{"date":56,"type":20},"2036-12",{"name":58,"class":59},"Zimmer Biomet","INDUSTRY",11,{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":68,"targetDuration":4,"studyType":70,"phases":4,"briefSummary":71,"conditions":72,"keywords":4,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100558071","post-market-clinical-follow-up-keriflex-100558071","NCT06546345","Post Market Clinical Follow-Up KeriFlex®","Effectiveness and Safety of the Silicone Joint Implant KeriFlex® and of Its Associated Instruments in the Treatment of MCP and PIP Arthritis: Post Market Clinical Follow up","Inclusion Criteria:\n\n* Adult patients (age ≥ 18 years)\n* Patients who are going to undergo arthroplasty of the metacarpophalangeal or proximal interphalangeal joint using a KeriFlex® implant in accordance with the instructions for use and the labelling in force.\n* Patients with rheumatoid arthritis, osteoarthritis or post-traumatic osteoarthritis\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women\n* Patients with an intellectual disability who cannot follow their surgeon's instructions\n* Patients with general surgery contraindications and particularly to the implantation of a KeriFlex® implant\n* Patients with acute or chronic, local or systemic infections\n* Metacarpal or phalanx destruction or poor bone quality preventing adequate fixation\n* Muscle loss, alteration or vascular deficiency in the affected finger\n* Patients with significant physical activity involving treated joint\n* Children, young growing patients with open epiphyses",{"count":69,"type":20},86,"OBSERVATIONAL","The general objective of this study is to assess the performance and safety of the KeriFlex® silicone joint implant and its associated instruments, used in accordance with the labeling and instructions in force.\n\nThe performance and safety of the KeriFlex® joint implant will be established in the short and long term with regard to the life cycle of the implant.",[73,35,74],"Rheumatoid Arthritis","Traumatic Arthritis","2025-09-04",{"date":77,"type":52},"2025-09-11",{"date":79,"type":52},"2023-11-14",{"date":81,"type":20},"2035-01",{"name":83,"class":59},"Keri Medical SA",3,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":92,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":21,"phases":95,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":4},"100425880","follow-up-study-for-participants-of-jointstem-investigator-initiated-trial-by-arthroscopy-100425880","NCT04825730","Follow-up Study for Participants of Jointstem Investigator Initiated Trial by Arthroscopy","Long-Term Extension Study of Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy in Patients With K-L Grade III Knee Osteoarthritis After 『JOINTSTEM』 Administration","Inclusion Criteria:\n\n* Participants of Jointstem IIT by arthroscopy (BS-JS-IIT1)\n* Participants who signed informed consent document of this study\n\nExclusion Criteria:\n\n* No applicable","20 Years",{"count":94,"type":20},14,[23],"This clinical trial is conducted to assess the long-term safety of \"jointstem\" in patients with degenerative knee arthritis who participated in the previous BS-JS-IIT1 investigator initiated trial.",[35,98],"Knee Arthritis",[100,101,102,103,104,105,106],"Stem cell","Adipose tissue derived mesenchymal stem cell","Osteoarthritis","degenerative arthritis","long term","Biostar","Rbio","NOT_YET_RECRUITING","2022-09-26",{"date":110,"type":52},"2022-09-28",{"date":112,"type":20},"2023-12-01",{"date":114,"type":20},"2029-12-31",{"name":116,"class":59},"R-Bio",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":124,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":21,"phases":127,"briefSummary":128,"conditions":129,"keywords":136,"overallStatus":107,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":152},"100315776","evaluation-of-outcomes-with-umbilical-cord-allograft-for-musculoskeletal-conditions-musculoskeletal-conditions-100315776","NCT03390920","Evaluation of Outcomes With Umbilical Cord Allograft for Musculoskeletal Conditions Musculoskeletal Conditions","Evaluation of Regenerative Medicine Outcomes With Umbilical Allograft for Musculoskeletal Conditions","Inclusion Criteria:\n\n1. Age 18 and over.\n2. Ability to attend follow up visits or at least converse on phone or complete email follow up forms.\n\n4\\) Competent to understand the study protocol and provide voluntary informed consent.\n\nExclusion Criteria:\n\n1. Active Infection\n2. Pregnancy, Lactating\n3. Clotting disorder",true,{"count":126,"type":20},200,[23],"The aim of the study is to determine the efficacy of an Amniotic Fluid Tissue Product for pain relief and functional improvements for all types of musculoskeletal conditions. The study is prospective, with outcome measures being obtained at numerous time points after the regenerative procedure.",[102,130,131,132,35,133,134,135],"Tendinitis","Sports Injury","Degenerative Disc Disease","Ligament Injury","Neuropathy","Pelvic Pain",[137,138,139,140,141,142],"regenerative medicine","arthritis","amniotic","stem cell","growth factor","cartilage","2021-09-10",{"date":145,"type":52},"2021-09-17",{"date":147,"type":20},"2022-01-01",{"date":149,"type":20},"2030-01-01",{"name":151,"class":59},"R3 Stem Cell",1]