[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"degenerative-lumbar-spondylolisthesis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:degenerative-lumbar-spondylolisthesis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100573671","comparison-of-endoscopic-lumbar-decompression-and-minimally-invasive-transforaminal-lumbar-interbody-fusionmis-tlif-for-degenerative-lumbar-spondylolisthesis-100573671",false,"NCT06749314","Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis","Comparison of Endoscopic Lumbar Decompression and Minimal Invasive Surgery Transforaminal Lumbar Interbody Fusion (MIS-TLIF) for Degenerative Lumbar Spondylolisthesis: A Randomized Controlled Study","MIS-TLIF","Inclusion Criteria:\n\n* Single level lumbar degenerative spondylolisthesis (Meyerding Grading Grade I or II).\n* Failed conservative treatment for at least 3 months.\n* No instability evidence of levels of lesion (Consideration from translation more than 5 mm or angulation change more than 10 degree in flexion and extension L-S plain films ).\n* Able to follow up for at least 12 months.\n* Patient who vorantarily agree to participate in research.\n\nExclusion Criteria:\n\n* Patients with severe foraminal stenosis diagnosed by MRI.\n* Patients who have previously undergone lumbar spine surgery (revision surgery).\n* Patients with other abnormalities in the lumbar spine, such as infection, tumors, or fractures.\n* Patients who cannot undergo surgery due to underlying conditions or who cannot maintain the prone position for extended periods.","ALL","40 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","Comparing the functional and radiographic outcomes in surgical treatment in failed conservative treatment, single-level low grade degenerative lumbar spondylolisthesis between Minimal Invasive Surgery Transforaminal Lumbar Interbody Fusion, which is conventional treatment recently, and Endoscopic Lumbar Decompression, which is minimal invasive in symptomatic treatment.",[27,28,29],"Degenerative Lumbar Spondylolisthesis","Lumbar Degenerative Disease","Lumbar Spinal Stenosis","NOT_YET_RECRUITING","2025-04-21",{"date":33,"type":34},"2025-04-22","ACTUAL",{"date":36,"type":21},"2025-05-01",{"date":38,"type":21},"2026-05-31",{"name":40,"class":41},"Queen Savang Vadhana Memorial Hospital, Thailand","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":53,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":42},"100547368","long-term-reoperations-after-lumbar-spinal-stenosis-surgery-100547368","NCT06407063","Long-term Reoperations After Lumbar Spinal Stenosis Surgery","Long-term Frequency of Reoperations After Micro-decompression Alone Versus Decompression and Instrumented Fusion in Patients With Lumbar Spinal Stenosis and Degenerative Spondylolisthesis","Inclusion Criteria:\n\n* operated between September 2007 and December 2015 labeled in the registry with both 'Spinal stenosis' and 'Degenerative spondylolisthesis'\n* operated on with decompression with or without an additional fusion\n\nExclusion Criteria:\n\n* operated with an anterior approach\n* had a former operation at index Level\n* was labeled with a degenerative scoliosis\n* was operated in more than 2 Levels\n* was operated with non-instrumented fusion\n* operated with a standard laminectomy with removing of the posterior midline structures or operated without magnifying devices was excluded from the micro-decompression group","18 Years",{"count":52,"type":21},794,"8 Years","OBSERVATIONAL","Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression. Sometimes, there is also a slippage of vertebra, degenerative spondylolisthesis. In such cases, instrumental stabilization (e.g. screws and rods) has been recommended. Even though additional fusion is more complex and riskier, and evidence in high-quality Scandinavian studies shows that it is unnecessary, decompression plus fusion is still the treatment of choice in the USA and most European countries. This reluctance to change clinical practice is mainly due to concerns about long-term results, especially higher reoperation rates among patients operated with decompression only. This register-based non-inferiority study aims to assess long-term reoperations among those treated with and without additional fusion surgery.",[27],[58,59,60,61,62],"Degenerative Spondylolisthesis","Treatment","Decompression alone","Instrumented fusion","Reoperations","RECRUITING","2024-12-11",{"date":66,"type":34},"2024-12-17",{"date":68,"type":34},"2007-09-19",{"date":70,"type":21},"2026-04-30",{"name":72,"class":41},"University Hospital of North Norway",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":42},"100556987","phase-1-long-term-safety-trial-with-nvdx3-100556987","NCT06532253","Long-term Safety Trial with NVDX3","Long-term Safety Bucket Trial with NVDX3, an Osteogenic Implant of Human Allogenic Origin.","X3LTFU","Inclusion Criteria:\n\n1. Patient being implanted with NVDX3.\n2. Previously participated to one of the NVDX3 core clinical trials.\n3. Patient accepts to comply to a yearly follow-up safety visit for 10 additional years\n4. Patient has understood and accepted to participate in the long-term follow-up study by signing the informed consent.\n\nExclusion Criteria:\n\nNo exclusion criteria are applicable.",{"count":82,"type":21},15,[84,85],"PHASE1","PHASE2","An study evaluating the long-term safety of all patients previously treated with NVDX3.",[88,27],"Distal Radius Fractures","2024-09-01",{"date":91,"type":34},"2024-09-05",{"date":93,"type":34},"2024-08-22",{"date":95,"type":21},"2036-03",{"name":97,"class":98},"Novadip Biosciences","INDUSTRY"]