[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"degenerative-scoliosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:degenerative-scoliosis":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,43,76,107,137],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100533473","clinical-outcome-measure-at-stryker-spine-100533473",false,"NCT06226272","Clinical Outcome Measure at Stryker Spine","Clinical Outcome Measure at Stryker Spine: COMPASS","COMPASS","Inclusion Criteria:\n\n• To be eligible to participate in the study, the potential subject must meet all inclusion criteria specific to the Stryker system being evaluated, please contact one of the participating investigators or see the device-specific cleared IFU, for further details.\n\nExclusion Criteria:\n\n• The exclusion criteria are based on the contraindications as presented in the Stryker device cleared IFUs, please contact one of the participating investigators or see the device-specific cleared IFU, for further details.","ALL","18 Years",{"count":20,"type":21},5222,"ESTIMATED","OBSERVATIONAL","This is a multicenter, prospective, retrospective, Post Market Clinical Follow-up (PMCF) study in subjects who have undergone or will undergo surgery utilizing one or more Stryker devices according to Stryker cleared Instructions for Use (IFU).",[25,26],"Degenerative Disc Disease","Degenerative Scoliosis",[28,29],"Device: Cervical or Thoracolumbar Spinal fusion","Device: Adult Spinal Deformities","RECRUITING","2026-06-23",{"date":33,"type":34},"2026-06-26","ACTUAL",{"date":36,"type":34},"2025-01-28",{"date":38,"type":21},"2032-01-29",{"name":40,"class":41},"VB Spine, LLC","INDUSTRY",7,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":75},"100351942","the-adult-degenerative-scoliosis-exercise-trial-pilot-study-100351942","NCT03862417","The Adult Degenerative Scoliosis Exercise Trial (Pilot Study)","ADSET","Inclusion Criteria:\n\n* Adults over 50 years old with degenerative scoliosis (n=20) with pain (\\>2\u002F10). Other inclusion criteria are: (1) curves 15°-45°.\n\nExclusion Criteria:\n\n* Curves over 50° are surgical candidates, and will be excluded. Patients who have had cortisone or anesthetic injections within the last 3 months, surgery or presenting contra-indications to exercises (fractures, cancer, severe cardio-vascular co-morbidities, or osteopenia) will be excluded.","50 Years",{"count":52,"type":21},20,"INTERVENTIONAL",[55],"NA","Adult degenerative scoliosis is the most common spine deformity in adults. Patients present a lateral curvature of the spine and vertebra rotation. Curves meeting indications for treatment affect 24% of the aging adult population. Adult scoliosis causes pain, curve progression, and cosmetic deformity affecting quality of life and function. Pain affects 90% of patients with AS. Other than surgery for severe cases and pain medication, very little non-operative treatments have been investigated. Scoliosis-specific exercises have shown promise in a single study in adults and in an Alberta adolescent study.\n\nThe goal of this pilot randomized controlled trial on the effect of Schroth exercises in adults with degenerative scoliosis compared to observation is to determine the feasibility of conducting a larger study. This study will help plan and secure funding for a larger study by examining the ability to recruit enough eligible participants, whether patients can follow the prescribed program session attendance and complete the home exercises prescribed. The early estimate the effects of the exercises on pain, quality of life, disability, deformity and posture measurements will help determine the potential of this approach and the likely success of a larger RCT. This study addresses a need of adults with degenerative scoliosis who do not meet surgical indications but still experience pain and disability by exploring a promising exercise approach.",[26],[59,60,61,62,63,64],"Scoliosis","Exercise","Pain","Posture","Quality of life","Disability","2026-05-04",{"date":67,"type":34},"2026-05-08",{"date":69,"type":34},"2020-09-01",{"date":71,"type":21},"2026-12-31",{"name":73,"class":74},"University of Alberta","OTHER",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":53,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":75},"100575639","phase-3-spinal-bracing-in-adults-with-painful-degenerative-scoliosis-a-randomized-controlled-open-trial-100575639","NCT06774898","Spinal Bracing in Adults With Painful Degenerative Scoliosis: a Randomized Controlled Open Trial","BRASCO","Inclusion Criteria:\n\n* Adults aged 40 to 75 years,\n* Degenerative thoracolumbar or lumbar scoliosis with Cobb angle for the largest curve greater than 20°on EOS® full-spine X-ray less than 1 year (this can be a de-novo scoliosis, or a degenerative scoliosis that appears on an idiopathic scoliosis), and\n* Low back pain with a duration more than 3 months\n* Low back pain with an intensity greater than 40 of 100 points on a self-administered numeric rating scale.\n* Patient able to give written informed consent prior to participation in the study Affiliation with a mode of social security (profit or being entitled).\n\nExclusion Criteria:\n\n* Spinal deformity secondary to a specific condition (e.g. fracture, infection, tumour, inflammatory rheumatic disease, neuromuscular disorder, genetic disorder),\n* History of spine surgery,\n* Morphotype and\u002For conditions making spinal bracing technically impossible (e.g. obesity, severe clinical sagittal and\u002For coronal malalignment, recent abdominal surgery etc)\n* Inability to speak and\u002For read French language,\n* Inability or refusal to wear a custom-molded lumbar-sacral orthosis,\n* Patients already wearing a custom-molded lumbar-sacral orthosis,\n* Cognitive disorders,\n* People under tutorship or curatorship,\n* Protected adults, and\n* Patients on AME (state medical aid),\n* Pregnant or breastfeeding women","40 Years","75 Years",{"count":86,"type":21},130,[88],"PHASE3","The purpose of this study is to compare the efficacy on low back pain intensity at 6 months after randomization of a custom-molded lumbar-sacral orthosis as an add-on therapy to usual care in people with painful adult degenerative scoliosis.",[26,91,92],"Scoliosis Idiopathic","Thoracolumbar Scoliosis",[59,94,95,96],"Low back pain","Spine","Bracing","NOT_YET_RECRUITING","2026-04-27",{"date":100,"type":34},"2026-05-01",{"date":102,"type":21},"2026-09",{"date":104,"type":21},"2030-09",{"name":106,"class":74},"Assistance Publique - Hôpitaux de Paris",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":115,"sex":17,"minAge":116,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":75},"100616770","gait-and-paraspinal-semg-in-degenerative-spinal-diseases-100616770","NCT07309926","Gait and Paraspinal sEMG in Degenerative Spinal Diseases","Comparative Analysis of Spatiotemporal Gait Parameters and Paraspinal Surface Electromyography Parameters in Degenerative Spinal Diseases: A Cross-Sectional Study Using Motion Capture and Electromyographic Ensemble Averaging","TDGKSEPDSD","Inclusion Criteria:\n\n1. Patients with the following single disease: degenerative scoliosis, coronal imbalance, lumbar spinal stenosis, lumbar disc herniation, spinal cord-type cervical spondylosis;\n2. Age ≥ 60 years, regardless of gender;\n3. Planned to undergo elective open spinal fusion surgery;\n4. Voluntarily participate in the study, understand and agree to the study content, and sign the informed consent form.\n\nExclusion Criteria:\n\n1. History of previous spinal surgery;\n2. Combined with other neuromuscular diseases (such as Parkinson's disease), inflammatory diseases (such as ankylosing spondylitis), infectious diseases (such as spinal tuberculosis), sepsis, tumors, or lower limb joint diseases that may cause low back and lower limb pain, affecting physical activity;\n3. Suffering from severe cardiovascular, cerebral, liver, or kidney disease;\n4. Suffering from mental illness, dementia, or unable to cooperate to complete clinical research.\n\n   * Skin rupture in the waist;",true,"60 Years",{"count":118,"type":21},120,"This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal conditions-including lumbar disc herniation (LDH), lumbar spinal stenosis (LSS), lumbar sagittal imbalance (LSI), degenerative lumbar scoliosis (DLS), and cervical spondylotic myelopathy (CSM)-alongside a healthy control group. The analysis focuses on spatiotemporal gait characteristics (step length, stride length, cadence), lower limb kinematics and kinetics (hip\u002Fknee\u002Fankle joint angles, moments, and powers during stance and swing phases), and surface EMG amplitudes (thoracic erector spinae, multifidus, gluteus maximus, and rectus abdominis muscles) during standardized walking tasks. Additionally, radiological parameters (e.g., pelvic incidence-lumbar lordosis mismatch, C2-C7 sagittal vertical axis, coronal Cobb angle) will be correlated with gait and muscle activation deviations. The study employs motion capture systems, force plates, and high-density EMG to objectively differentiate disease-specific movement impairments. Findings from this study may establish biomechanical and neuromuscular signatures for each degenerative condition, providing a framework for personalized rehabilitation strategies, gait retraining, and surgical outcome assessment in spinal disorders. Comparative analysis with healthy controls will further elucidate pathological alterations in gait and muscle recruitment patterns caused by degenerative spinal diseases.",[121,26,122,123,124,125,126,127],"Adult Spinal Deformity","Sagittal Deformity","Sagittal Imbalance","Coronal Vertical Axis","Lumbar Spinal Stenosis","Lumbar Disc Herniation","Cervical Spondylosis With Myelopathy","2025-12-15",{"date":130,"type":34},"2025-12-30",{"date":132,"type":21},"2025-12-10",{"date":134,"type":21},"2029-12-01",{"name":136,"class":74},"Xuanwu Hospital, Beijing",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":53,"phases":147,"briefSummary":148,"conditions":149,"keywords":4,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":157,"locationsCount":75},"100552213","priority-matching-correction-technique-in-degenerative-lumbar-scoliosis-100552213","NCT06470165","Priority-Matching Correction Technique in Degenerative Lumbar Scoliosis","Global Coronal Malalignment in Degenerative Lumbar Scoliosis and Priority-Matching Correction Technique to Prevent Postoperative Coronal Decompensation","PMCTDLS","Inclusion Criteria:\n\n1. A diagnosis of DLS based on radiography and previous medical record,\n2. Age \\> 50 years\n\nExclusion Criteria:\n\n1. Leg length discrepancy,\n2. A history of spinal or pelvic surgery,\n3. A history of neuromuscular diseases, arthritis or tumor.",{"count":146,"type":21},200,[55],"Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with degenerative lumbar scoliosis (DLS) who underwent correction surgery with reference to our priority-matching correction technique and the standard reported by Obeid and colleagues. Our findings may provide tangible guidance for surgical decision-making in DLS.",[150,59,26],"Degenerative Lumbar Disease","2024-06-17",{"date":153,"type":34},"2024-06-24",{"date":155,"type":21},"2024-08-21",{"date":71,"type":21},{"name":136,"class":74}]