[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dementia-prevention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dementia-prevention":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,57],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":35,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100620930","the-brain-health-pro-online-risk-factor-reduction-study-to-prevent-dementia-100620930",false,"NCT07364019","The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia","The Brain Health PRO Online Risk Factor Reduction Study for The Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia","BHPROOF","Inclusion Criteria:\n\n* Completion and documentation of the electronic Informed Consent Process (from the participant)\n* Sufficient proficiency in English or French to undergo online assessments and participate in an online educational program.\n* Technical ability to participate in an online educational program and remote assessments (i.e., regularly have access to a computer or tablet with an internet connection; have access to a desktop or laptop computer with an internet connection at least once every 6 months; ability to send and receive emails; ability to complete online assessments)\n* Sufficient vision to participate in an online educational program and complete online cognitive testing\n* Ages 50-80\n* Classified as being at increased risk of dementia based on at least one of the following:\n\n  * First-degree family history of dementia\n  * Education level at or below high school (grade 12 or less)\n  * Self-Reported: Hypertension, Hypercholesterolemia, Body Mass Index \\> 30 kg\u002Fm2 (derived from NIH Metric BMI Calculator), or Physical Inactivity (active is defined as engaging in a minimum of 20- 30 min of physical activity causing sweating and breathlessness, at least 2 times a week)\n\nExclusion Criteria:\n\n* Individuals who have a clinical diagnosis of Dementia (based on self-report)\n* Individuals who are currently participating in or have participated in a past study involving BHPro",true,"ALL","50 Years","80 Years",{"count":22,"type":23},700,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro). The BHPro intervention is designed to address modifiable risk factors for dementia through a 6-month, fully online, educational program conveying the best available evidence for lifestyle changes that can mitigate dementia risk, and foster engagement toward one's own brain health. Achieving lifestyle changes in a diverse Canadian population through online education would be a major achievement in dementia prevention in Canada, with widespread personal and socioeconomic benefits.\n\nEligible participants will be randomly assigned to either start Brain Health PRO immediately or in 6 months (delayed-start control group). All participants will have the opportunity to have access to BHPro for 6 months during the course of the study and will have open access to all content for 12 months following the initial 6-month intervention. Participation will last from 18-24 months depending on group assignment.",[29,30,31,32,33,34],"Dementia Prevention","Subjective Cognitive Impairment","Mild Cognitive Impairment","Cognitive Change","Lifestyle Intervention","Dementia Education",[36,37,38,39,40,41,42,43],"dementia education","at risk for dementia","lifestyle intervention","dementia reduction","dementia risk factor","dementia prevention","cognitive impairment","Alzheimer risk","RECRUITING","2026-05-14",{"date":47,"type":48},"2026-05-19","ACTUAL",{"date":50,"type":48},"2026-05-07",{"date":52,"type":23},"2028-12-31",{"name":54,"class":55},"University of British Columbia","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":18,"minAge":64,"maxAge":4,"enrollmentInfo":65,"targetDuration":4,"studyType":24,"phases":67,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":56},"100550950","effectiveness-of-non-pharmacological-interventions-for-dementia-prevention-in-elderly-patients-with-mild-cognitive-impairment-100550950","NCT06453746","Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment","Effectiveness of Dementia Prevention in Elderly Patients With Mild Cognitive Impairment at Nhân dân Gia Định Hospital, Hồ Chí Minh City","Inclusion Criteria:\n\n* Subjects diagnosed with mild cognitive impairment:\n\n  * Cognitive complaints from the subject or a family member.\n  * Report a decline in cognitive function compared to the subject's previous ability over the past year OR\n  * Evidence from clinical assessment, specifically here is MMSE screening with results of 24-29 points.\n  * Subjects did not suffer major impacts from cognitive complaints on daily life.\n  * No prior diagnosis of dementia.\n* Ensure transportation from living location to hospital.\n* Have at least one relative or caregiver who can supervise the subject's daily activities.\n* Stable chronic underlying conditions (diabetes, hypertension).\n* Consent to participate in the study.\n\nExclusion Criteria:\n\n* Don't know Vietnamese writing.\n* Audio-visual ability does not meet the requirements of assessment tests and prevention programs.\n* Systemic diseases are contraindications\u002F restriction to participation in programs and\u002For cause secondary cognitive impairment (traumatic brain injury, stroke, brain tumor, parkinsonism, epilepsy, acute coronary artery disease, acute myocardial infarction, bone fractures...).\n* The assessment score on the Geriatric Depression Scale (GDS-15) is ≥ 5 points.\n* Diagnosed with other mental disorders that may limit the ability to understand, communicate and work in groups (schizophrenia, mania, bipolar disorder, dissociative disorder, generalized anxiety disorder).\n* Currently participating in another research program on dementia prevention or a research program on medication to prevent dementia within the last 3 months.\n* Taking medications that may affect cognitive function, such as benzodiazepines, hypnotics, and antipsychotics.\n* Alcohol abuse: drinking alcohol daily or consuming more than 14 units of alcohol per week (equivalent to 10 grams of ethanol, as defined by the Ministry of Health); diagnosed with alcohol dependence or currently being treated for mental illness due to alcohol dependence.\n* Do not agree to participate in the study.","60 Years",{"count":66,"type":23},192,[26],"The aims of this study is to evaluate the effectiveness of non-pharmacological interventions program in preventing progression from mild cognitive impairment to dementia in patients with mild cognitive impairment in the short term, at Nhân dân Gia Định Hospital, Hồ Chí Minh City.",[31,29],"2024-09-03",{"date":72,"type":48},"2024-09-19",{"date":74,"type":48},"2024-08-26",{"date":76,"type":23},"2026-12",{"name":78,"class":55},"Gia Dinh People Hospital"]