[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"demyelinating-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:demyelinating-disorder":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100557708","sun-yat-sen-cohort-of-cns-idiopathic-inflammatory-demyelinating-diseases-100557708",false,"NCT06541626","Sun Yat-Sen Cohort of CNS Idiopathic Inflammatory Demyelinating Diseases","Sun Yat-Sen Prospective Cohort Study of Central Nervous System Idiopathic Inflammatory Demyelinating Diseases","Inclusion Criteria:\n\n1. Patients aged 18-65 years with central nervous system idiopathic inflammatory demyelinating diseases (CNS IIDD);\n2. The clinical syndrome of the attack meets one of the following: MS, NMOSD, MOGAD, ADEM, clinically isolated syndrome, demyelinating encephalopathy, demyelinating myelitis, or brainstem encephalitis (see below A-E);\n3. Agree to participate in this study and sign the informed consent form.\n\nExclusion Criteria:\n\n1. History of tumors or diagnosis of central nervous system tumors;\n2. Infectious lesions of the central nervous system;\n3. Hereditary, metabolic, toxic, vascular, or traumatic demyelinating diseases of the brain\u002Fspinal cord;\n4. Non-compliance with treatment and follow-up.","ALL","18 Years","65 Years",{"count":20,"type":21},450,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about pathogenesis and clinical prognosis of CNS IIDD in the Chinese population and to provide evidence-based clues for clinical treatment decisions.\n\nThe main questions it aims to answer are:\n\nQuestion 1: Clarify the clinical characteristics and prognostic factors of various diseases (MS, NMOSD, MOGAD, etc.) within IIDD in the Chinese population.\n\nQuestion 2: Analyze the relationship between biomarkers and the occurrence, progression, and prognosis of CNS IIDD cases in our hospital.\n\nParticipants will\n\n1. Receive the recommended diagnosis and treatment plans from current international and national guidelines or expert consensus, without additional special interventions.\n2. Receive clinical evaluation, follow-up, and management from dedicated neuroimmunology specialists.",[25,26,27,28,29,30],"Multiple Sclerosis, MS","Neuromyelitis Optica Spectrum Disorders","Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease","Acute Disseminated Encephalomyelitis","Clinically Isolated Syndrome","Demyelinating Disorder",[32,33],"CNS IIDD","follow-up","RECRUITING","2024-08-02",{"date":37,"type":38},"2024-08-07","ACTUAL",{"date":40,"type":38},"2024-01-01",{"date":42,"type":21},"2035-12-31",{"name":44,"class":45},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER"]