[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental-enamel\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental-enamel":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100618320","retention-of-pits-and-fissure-sealants-on-non-carious-vs-initial-carious-enamel-lesions-in-posterior-teeth-100618320",false,"NCT07330089","Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth","Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth, a Non Randomized Clinical Study","Inclusion Criteria:\n\n* Fully erupted maxillary and mandibular 1st and 2nd molars with antagonist teeth present.\n* ICDAS score 0,I,II\n* Age 7 to 18 years\n* Both genders included\n\nExclusion Criteria:\n\n* permanent teeth requiring restorations,\n* uncooperative patients\n* patients unwilling for follow-ups\n* molars withy antagonist teeth not present\n* mentally and physically handicapped patients\n* patients with parafunctional habits\n* patients undergoing orthodontic treatments",true,"ALL","7 Years","18 Years",{"count":21,"type":22},420,"ESTIMATED","3 Months","OBSERVATIONAL","This clinical study is planned to be conducted to compare retention rates of pits and fissure sealants on non carious (ICDAS score 0) vs Initial carious enamel lesions (ICDAS Score 1,2) in posterior permeant teeth at 3 months, 6 months and 12 months follow-up. This will help us guide follow-up strategies for optimal caries prevention.",[27,28,29],"Dental Enamel","Dental Enamel Hypomineralization","Dental Enamel Hypoplasia",[31,32,33],"pit and fissure sealants","pit sealant","fissure sealant","RECRUITING","2026-05-22",{"date":37,"type":38},"2026-05-26","ACTUAL",{"date":40,"type":38},"2025-12-27",{"date":42,"type":22},"2027-06-30",{"name":44,"class":45},"Foundation University Islamabad","OTHER"]