[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental-implants-single-tooth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental-implants-single-tooth":23},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,65,92],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":25,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100639159","immediate-loading-of-implants-in-the-aesthetic-zone-using-three-dimensionally-printed-provisional-crowns-a-1-year-prospective-case-series-study-100639159",false,"NCT07629752","Immediate Loading of Implants in the Aesthetic Zone Using Three-dimensionally Printed Provisional Crowns: a 1-year Prospective Case Series Study","Inclusion Criteria:\n\n* The patient is 18 years or older;\n* The implant region is an incisor (central or lateral), cuspid or first bicuspid in the maxilla; the adjacent teeth are natural teeth;\n* Sufficient healthy and vital bone after alveolar ridge preservation to insert a dental implant with a minimum length of 10 mm and at least 3.5 mm in diameter with initial stability \\> 45 Ncm;\n* The implant site must be free from infection;\n* Adequate oral hygiene (modified plaque index and modified sulcus bleeding index ≤ 1);\n* Sufficient mesio-distal, bucco-lingual, and interocclusal space for placement of an anatomic crown;\n* The provisional crown can be designed free from occlusal contact;\n* The patient is capable of understanding and giving informed consent.\n\nExclusion Criteria:\n\n* Medical and general contraindications for the surgical procedures;\n* Presence of an active and uncontrolled periodontal disease;\n* Bruxism;\n* Smoking\n* A history of local radiotherapy to the head and neck region.","ALL","18 Years",{"count":18,"type":19},30,"ESTIMATED","OBSERVATIONAL","• Background There is a growing tendency to place a provisional crown immediately following implant placement. Clinical advantages are shortening of treatment duration and soft tissue guiding during healing resulting in better aesthetic outcomes. It was shown that good esthetic results can be achieved on the long term with immediate provisionalization of single-tooth implants placed in either fresh extraction sockets or after alveolar ridge preservation\u002Freconstruction in the maxillary esthetic zone.\n\nOne recent development in three-dimensional printing is digital press stereolithography (DPS), which overcomes the challenges of printing highly-filled viscous materials. This enables the use of more durable materials than traditional three-dimensionally printed provisional crowns and allows for rapid additive production of prosthetic restorations.\n\nUntil date, no studies have been described investigating immediate loading of implants in the aesthetic zone using three-dimensional DPS-printers and their impact on patient-satisfaction.\n\n* Main research question The purpose of this one-year prospective case series study is to perform an assessment of patient-reported outcomes of single-tooth implants with immediate provisionalization using three-dimensionally printed provisional crowns.\n* Design (including population, confounders\u002Foutcomes) The study design is a prospective, single-arm observational study for evaluation of 30 patients with a failing tooth in the maxillary aesthetic region to be treated with an implant-supported provisional and definitive restoration by means of a provisional and definitive crown. Outcomes: registration of time\u002Fcomplications during the diagnostic\u002Fplanning\u002Fmanufacturing process, evaluation of clinical and radiographical performance and aesthetic outcome.\n* Expected results Satisfying results for patients and professionals (VAS-scores and PES\u002FWES-scores)",[23,24],"Dental Implants, Single-tooth","Crown",[26,27],"Implant placement","Immediate provisional","NOT_YET_RECRUITING","2026-06-01",{"date":31,"type":32},"2026-06-05","ACTUAL",{"date":34,"type":19},"2026-07-01",{"date":36,"type":19},"2027-07-01",{"name":38,"class":39},"University Medical Center Groningen","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":50,"conditions":51,"keywords":53,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":40},"100625820","immediate-implant-placement-and-immediate-restoration-with-prefabricated-provisionals-100625820","NCT07427602","Immediate Implant Placement and Immediate Restoration With Prefabricated Provisionals","Immediate Implant Placement and Immediate Restoration With Prefabricated Provisionals: A Retrospective Case Series Study","Inclusion Criteria:\n\n* The patient is 18 years or older;\n\n  * The implant region is an incisor (central or lateral), cuspid or first bicuspid in the maxilla; the adjacent teeth are natural teeth;\n  * Patient is treated with an immediate implant and an immediate prefabricated provisional restoration;\n  * The definitive restoration is at least one year in function\n\nExclusion Criteria:\n\n* Reference intraoral radiograph not available in the medical record",{"count":49,"type":19},50,"* Background\n* There is a growing tendency to place a provisional restoration immediately following implant placement. Clinical advantages are shortening of treatment duration and soft tissue guiding during healing resulting in better esthetic outcomes. Provisional restorations can be made either chair-side or in the dental laboratory after implant placement. Nowadays, digital planning makes it possible to fabricate the provisional restoration before implant surgery. The advantage of this technique is that the treatment procedure of placement of the provisional restoration immediately after implant placement is much less time consuming for the patient and due to its machined polished character possibly beneficial for soft tissues.\n* Main research question The aim of this retrospective case series study, with full digital workflow, is to evaluate single tooth implant treatment after immediate implant placement in the maxillary aesthetic region, with respect to registration of possible complications during the time of placement and evaluation of the prefabricated provisional registration and evaluation of clinical and radiographical performance and aesthetic outcome with the definitive restoration after at least 1 year in function.\n* Design (including population, confounders\u002Foutcomes) The study design is a retrospective, single-arm observational study for evaluation of 50 patients with a failing tooth in the maxillary aesthetic region, which were treated with an implant-supported provisional and definitive restoration by means of a digital workflow. Outcomes: registration of possible complications during the time of placement and evaluation of the provisional registration and evaluation of clinical and radiographical performance and aesthetic outcome with the definitive restoration.\n* Expected results Satisfying results for patients and professionals (VAS-scores and PES\u002FWES-scores).",[23,52,24],"Immediate Dental Implant Placement",[54,55,56],"Immediate implant placement","Maxillary esthetic region","Prefabricated provisional","2026-02-20",{"date":59,"type":32},"2026-02-23",{"date":61,"type":19},"2026-03-01",{"date":63,"type":19},"2026-11-01",{"name":38,"class":39},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":40},"100593046","alveolar-ridge-preservation-versus-spontaneous-healing-100593046","NCT07001345","Alveolar Ridge Preservation Versus Spontaneous Healing","Alveolar Ridge Preservation (ARP) Versus Spontaneous Healing in Large Buccal Bone Defects After Tooth Extraction in the Posterior Mandible","ARP versus SH","Inclusion Criteria:\n\n* A minimum age of 18 years old\n* In need for extraction of a single (pre)molar in the mandible that needs to be replaced by an implant\n* At least one adjacent tooth\n* A buccal bone defect after extraction of 50% or more\n\nExclusion Criteria:\n\n* Active periodontal disease\n* Uncontrolled diabetes mellitus\n* History of or current chemotherapy or radiation in the head and neck area\n* History of or current use of medication related to osteonecrosis of the jaw\n* Heavy and moderate smokers (\\>5 cigarettes a day)\n* Unable to maintain basic oral health (physical and\u002For mental)\n* Pregnancy (in case of pregnancy, the treatment is postponed until after the delivery)",true,{"count":75,"type":19},66,"INTERVENTIONAL",[78],"NA","Rationale: To determine the effect of alveolar ridge preservation (ARP) versus spontaneous healing (SH) in large buccal bone defects in the posterior mandible.\n\nObjective: To evaluate whether ARP using a xenograft (XG) (Cerabone plus) or an allograft (AG) (Maxgraft granules) covered by a membrane (Jason membrane) reduces the need for additional bone augmentation either prior to or during implant placement in the posterior mandible compared to spontaneous healing Study design: Prospective randomized clinical study with 10-year follow-up.\n\nStudy population:\n\nInclusion criteria: patients are 18 years or older and in need for extraction of a (pre)molar in the posterior mandible with at least one adjacent tooth and a buccal bone defect of \\>50%.\n\nExclusion criteria: the presence of active periodontal disease, uncontrolled diabetes mellitus, a history of or current use of chemotherapy or radiation in the head and neck area, history of or current use of medication related to osteonecrosis of the jaw, smoking (\\> 5 cigarettes a day, disability (physical and\u002For mental), making the patient unable to maintain basic oral health or follow the study protocol, pregnancy (in case of pregnancy, the treatment is postponed until after the delivery).\n\nIntervention (if applicable): Atraumatic extraction of a (pre)molar in the posterior mandible will be performed. Patients will then be included based on the dimensions of the buccal bone defect (buccal bone defect of \\>50%). 66 patients will be randomly divided in either the XG group, the AG group or the SH group (control). In the ARP groups (XG and AG), following tooth extraction, ARP will be performed using either a XG (Cerabone plus) or an AG (Maxgraft granules), both covered by a membrane (Jason membrane). In the control group, the alveolus will be left for spontaneous healing, following tooth extraction. After 4-6 months, a cone bean computed tomography (CBCT) scan will be performed to determine the possibility of implant placement with or without additional augmentation. Implant placement will be performed in all groups with or without guided bone regeneration (GBR).\n\nMain study parameters\u002Fendpoints: Frequency of additional augmentation at implant placement.",[23,81,82],"Alveolar Ridge Preservation","Guided Bone Regeneration","2025-05-23",{"date":85,"type":32},"2025-06-03",{"date":87,"type":19},"2025-06-01",{"date":89,"type":19},"2035-06-01",{"name":91,"class":39},"Erasmus Medical Center",{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":73,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":76,"phases":100,"briefSummary":101,"conditions":102,"keywords":105,"overallStatus":108,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":40},"100547384","effect-of-abutment-configuration-on-peri-implant-soft-and-hard-tissue-in-the-esthetic-zone---randomized-clinical-trial-100547384","NCT06407271","Effect of Abutment Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial","Effect of Abutment 3-dimensional Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial","Inclusion Criteria:\n\n* patients over 18 years\n* good general health\n* good oral hygiene (FMPS \\\u003C 25%)\n* healthy periodontium (PPD \\\u003C 4mm)\n* thick phenotype\n* maxilla anterior region (extended to 15-25 positions)\n* solo missing teeth, intact adjacent teeth\n* type 1 alveolar shape after extraction 1\n* retained occlusion\n* baseline buccal bone wall thickness at least 1.5 mm, based on intact CBCT scan\n* patient voluntarily accepts and signs the information and consent form for the study\n\nExclusion Criteria:\n\n* general ill health\n* general surgical or oral surgery contraindication\n* a patient who has undergone local radiotherapy\n* active periodontal inflammation, inflammation of the alveolar cavity\n* smoking\n* posterior region\n* pregnancy, lactation\n* psychological or mental involvement affecting individual plaque control\n* presence of an implant adjacent to the planned implant\n* inadequate oral hygiene\n* need for vertical bone augmentation\n* gingival recession\n* Inappropriate implant position for screw fixation\n* bruxism",{"count":18,"type":19},[78],"The aims of our study are to investigate in patients with immediate implantation replacing a single tooth in the maxillary anterior (#FDI 15-25) region the effect of (a) custom vs cylindrical stock healing abutments, then (b) screw retained single ceramic crowns, on the peri implant hard- and soft-tissue formation and blood flow.",[103,104],"Dental Implants, Single-Tooth","Dental Implant-Abutment Design",[106,107,103,104],"Peri-Implant Tissue Management","CAD-CAM","RECRUITING","2024-05-06",{"date":111,"type":32},"2024-05-09",{"date":113,"type":32},"2023-12-13",{"date":115,"type":19},"2028-12-30",{"name":117,"class":39},"Semmelweis University"]