[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental-pulp-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental-pulp-diseases":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100257917","evaluation-of-three-pulp-vitality-tests-100257917",false,"NCT02636504","Evaluation of Three Pulp Vitality Tests","Inclusion Criteria:\n\n* Criteria for inclusion in the study will be that the individual has teeth that require endodontic treatment and patient is willing to undergo two additional vitality tests which will take about 20 minutes of additional time.\n\nExclusion Criteria:\n\n* No group of special subjects or vulnerable population is being targeted in this study.",true,"ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","The objectives of this study are to determine the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of laser Doppler flowmetry in determining the vitality of teeth and comparing with those of electric pulp testing and cold testing.",[24,25],"Dental Pulp Diseases","Dental Pulp Vitality Testing",[27,28],"Pulp vitality","Pulp testing","NOT_YET_RECRUITING","2026-02-02",{"date":32,"type":33},"2026-02-04","ACTUAL",{"date":35,"type":20},"2026-12",{"date":37,"type":20},"2027-12",{"name":39,"class":40},"Columbia University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":41},"100615355","optimizing-pulp-management-in-autotransplantation-of-mature-third-molars-a-randomized-controlled-trial-100615355","NCT07291531","Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A Randomized Controlled Trial","Optimizing Pulp Management Strategies for Autotransplantation of Fully Developed Third Molars: A Three-Arm Randomized Controlled Trial","OPuM-ATM3","Inclusion Criteria:\n\n1. Aged 18-40 years.\n2. Requires extraction of a non-restorable first or second molar AND possesses a fully developed, morphologically healthy ipsilateral third molar as a donor tooth.\n3. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Presence of acute infection or insufficient bone volume at the recipient site.\n2. Donor tooth exhibits caries, periapical pathology, or periodontal disease.\n3. Uncontrolled systemic disease (e.g., diabetes, immunosuppression), pregnancy, or lactation.\n\n   Smoking habit of \\>10 cigarettes per day.\n4. Inability or unwillingness to comply with the long-term follow-up schedule.","40 Years",{"count":52,"type":20},360,"INTERVENTIONAL",[55],"NA","This study aims to find the best way to use your own healthy wisdom tooth to replace the bad tooth. After transplantation, how to manage the \"tooth nerve\" (dental pulp) inside the tooth is a key question. Currently, doctors have three different management strategies, but it is not clear which one is most beneficial for long-term success.\n\nThis study will compare these three strategies:\n\nPerforming standard root canal treatment (removing the tooth nerve) a few weeks after transplantation.\n\nPerforming a special procedure to treat and fill the root tip during the transplant surgery, followed by root canal treatment later.\n\nSimply trimming the root tip during the transplant surgery, hoping to preserve the vitality of the tooth nerve and thereby avoid subsequent root canal treatment.\n\nIf you agree to participate, you will be randomly assigned to one of these groups to receive treatment. Afterwards, we will need to schedule regular check-ups for you over a period of 5 years (including X-rays and examinations) to monitor the healing of the transplanted tooth, check for any problems, and assess the status of the tooth nerve.\n\nYour participation will help us identify the most effective and long-lasting treatment method, thereby benefiting future patients in similar situations.",[58,24,59],"Tooth Avulsion","Tooth, Impacted",[61,62,63,64,65,66],"Autotransplantation","Third molar","Root canal therapy","Apical surgery","Root-end resection","mature tooth","2025-12-07",{"date":69,"type":33},"2025-12-18",{"date":71,"type":20},"2026-01",{"date":73,"type":20},"2032-06",{"name":75,"class":40},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":53,"phases":87,"briefSummary":88,"conditions":89,"keywords":96,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":4},"100567965","caries-location-and-its-effect-on-the-success-rate-of-indirect-pulp-treatment-in-primary-molars-100567965","NCT06675058","Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars","Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars: A Comparative Clinical Study","Inclusion Criteria:\n\n* Participant criteria:\n\n  1. Children aged between 3-7 years\n  2. Children in complete physical and mental health.\n  3. Children with free medical history.\n  4. Patient with favorable attitudes, which will be assessed by using Frankl behavior rating.\n\nTeeth criteria:\n\n1. Primary molars with active occlusal or proximal deep caries.\n2. Teeth with reversible pulpitis\n3. Asymptomatic teeth or teeth with provoked pain of short duration\n4. Teeth should be restorable.\n\nExclusion Criteria:\n\n* Clinical signs or symptoms suggesting evidence of pulp degeneration or a non -vital tooth such as:\n\n  * Clinical symptoms or history indicating irreversible pulpitis as (spontaneous pain, throbbing pain).\n  * Tenderness to percussion.\n  * Soft tissue swelling, abscess, draining fistula or sinus tracts.\n  * Pathological Tooth mobility.\n\nPresence of the following Radiographic criteria:\n\n* Periapical or inter-radicular radiolucency.\n* Internal or external pathological root resorption.\n* Furcation involvement\n* Widening of periodontal space.","3 Years","7 Years",{"count":86,"type":20},50,[55],"The following study will be created to evaluate how the location of caries affects the effectiveness of indirect pulp treatment in primary molars. aiding in the development of evidence-based recommendations for pediatric dentists.",[90,24,91,92,93,94,95],"Deep Caries Lesion of Primary Teeth","Deep Proximal Caries","Deep Occlusal Caries","Reversible Pulpitis","Pulpitis","Decayed Teeth",[97,98,99,100,101,102,103,104,93,94,105,106],"Indirect Pulp Treatment","IPT","Caries location","Caries Site","Proximal and occlusal Caries","Proximal Caries","Occlusal Caries","Pulp Therapy","deciduous teeth","Caries in milk teeth","2024-11-04",{"date":109,"type":33},"2024-11-05",{"date":111,"type":20},"2024-12-01",{"date":113,"type":20},"2026-08-18",{"name":115,"class":40},"Cairo University"]