[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental-restoration\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental-restoration":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,68,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100643699","additive-vs-subtractive-manufacturing-for-endocrown-fabrication-a-24-month-rct-100643699",false,"NCT07633574","Additive vs Subtractive Manufacturing for Endocrown Fabrication: A 24-Month RCT","Additive Versus Subtractive Manufacturing for Endocrown Fabrication: A Clinical Comparison of 3D-Printed Ceramic-Filled Photopolymer Resin and CAD\u002FCAM Milled Resin Nano-Ceramics Endocrowns in Posterior Teeth - A 24-Month Randomized Controlled Trial","ENDO-3D","Inclusion Criteria:\n\n* Age 25-45 years, male or female\n* Endodontically treated molar tooth with radiographically confirmed treatment success and no clinical signs of failure\n* Sufficient remaining coronal structure for endocrown preparation: minimum three walls, wall thickness 1.5 mm or greater, pulp chamber depth 3 mm or greater, supragingival preparation margins\n* Completely erupted tooth with intact periodontal support\n* Minimum of 20 occluding teeth\n* Satisfactory oral hygiene status\n* Capable of providing written informed consent and committed to scheduled follow-up visits\n\nExclusion Criteria:\n\n* Diagnosed parafunctional habit or nocturnal bruxism\n* Uncontrolled systemic illness or physical disability precluding safe participation\n* Heavy tobacco use\n* Current or suspected pregnancy\n* Periapical disease or radiographic signs of endodontic failure\n* Evidence of pathological tooth wear or occlusal erosion\n* Moderate-to-severe periodontitis or tooth with hopeless prognosis\n* Radiographic or clinical evidence of vertical root fracture\n* Impaired decision-making capacity or anticipated non-compliance","ALL","25 Years","45 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial (RCT) compares the 24-month clinical performance of endocrown restorations fabricated by two digital manufacturing pathways: additive manufacturing using 3D-printed ceramic-filled photopolymer resin (VarseoSmile TriniQ, BEGO) versus subtractive computer-aided design\u002Fcomputer-aided manufacturing (CAD\u002FCAM) milling from hybrid nano-ceramic blocks (HC Hard Block, Shofu). Sixty endocrowns will be placed in endodontically treated posterior molars and evaluated using modified United States Public Health Service (USPHS) criteria at 6, 12, and 24 months. The trial is conducted at the Conservative Dentistry Department, Faculty of Dentistry, Cairo University.",[28,29,30],"Tooth, Nonvital","Dental Restoration","Endodontically Treated Teeth","NOT_YET_RECRUITING","2026-06-04",{"date":34,"type":35},"2026-06-08","ACTUAL",{"date":37,"type":22},"2026-06",{"date":39,"type":22},"2028-09",{"name":41,"class":42},"Cairo University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":65,"locationsCount":67},"100602828","3mtm-filtektm-supreme-flowable-composites-for-class-iv-and-veneers-100602828","NCT07128589","3M(TM) Filtek(TM) Supreme Flowable Composites for Class IV and Veneers","Clinical Evaluation of 3M(TM) Filtek(TM) Supreme Flowable Composites for Class IV and Veneers","Inclusion Criteria:\n\n* Age between 18 -75 years old\n* must be willing and able to provide informed consent to participate in the study\n* must be available for the required post-operative follow-up study visits\n* must be in good general health\n* must be in good oral health hygiene (FMPS \\\u003C 20%)\n* have at least 6 anterior maxillary teeth\n* Central and lateral incisors with class IV or Veneer indications. Veneers will be performed exclusively with its contralateral teeth (pairs).\n\nExclusion Criteria:\n\n* Single tooth veneers\n* Canines\n* Periodontal disease\n* Pulpal diseases\n* Occlusal dysfunctions (end-to-end bite)\n* Lack of occlusal stability\n* Missing posterior teeth, affecting the occlusal distribution\n* Study tooth, adjacent tooth, or opposing tooth with mobility \\> grade 2 using the Miller's tooth mobility index\n* Systemic or local disorders that contra-indicate the dental procedures needed in this study\n* Rampant, uncontrolled caries\n* Heavy use of smoking tobacco (1 pack or equivalent a day) or chewing tobacco\n* Evidence of xerostomia\n* Evidence of severe bruxing or clenching, or in need of Temporomandibular Joint (TMJ) related therapy\n* Known allergic reaction and\u002For sensitivity to research materials being used\n* Condition or history of chronic use of anti-inflammatory, analgesic (pain), and\u002For mind altering drugs for medical (including psychiatric) and pharmacotherapeutic therapies that might alter the perception of pain\n* Tooth surface loss (attrition, erosion, abrasion, or abfraction) on study tooth or adjacent teeth that could impact the perception of pain.\n* Taking part in a clinical evaluation of any other dental material\n* In the opinion of the Investigator, unsuitable for enrollment in the study for reasons other than those specified in the above exclusion criteria\n* Pregnant at the time of enrollment or procedure visit (determined by urine pregnancy test).","18 Years","75 Years",{"count":53,"type":22},75,[25],"This clinical study aims to evaluate the clinical performance of 3M™ Filtek™ Supreme Flowable Composite in class IV and veneer indication. Follow-ups of 7 days, 6, 12, and 24 months will be conducted following an Fédération Dentaire Internationale (FDI) modified score (2023). A minimum of 50 Class IV and 25 veneers will be included in the evaluation. Research data and pictures will be provided for each patient pre-op and at 7 days (baseline, 6 months, 12 months and 24 months. Evaluation will be conducted by two calibrated evaluators different from the operator according to FDI clinical criteria.",[29,57],"Dental Veneers","RECRUITING","2026-02-26",{"date":61,"type":35},"2026-02-27",{"date":63,"type":35},"2025-08-07",{"date":39,"type":22},{"name":66,"class":42},"New York University",1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":17,"minAge":50,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":67},"100548179","prosthetic-outcomes-and-clinical-performance-of-implant-supported-zirconia-crowns-100548179","NCT06417632","Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns","Prosthetic Outcomes and Clinical Performance of Two Types of Monolithic Zirconia-based Screw-retained Crowns. A Randomized Clinical Trial","Inclusion Criteria:\n\n* Partially edentulous area with suitable restorative space more than 5.5 mm\n* At least 18 years of age\n* Opposing natural teeth or fixed restorations supported by teeth or implants.\n* Generally good health (ASA I, ASA II)\n* Participant complies with good oral hygiene practices (BOP and PI less than 20%)\n* Healthy integrated implant\u002Fs without signs of periimplantitis in the posterior site planned for single tooth replacement (in premolar or molar areas)\n* Patients received bone-level implants, RC Straumann Implants.\n\nExclusion Criteria:\n\n* Inability to provide consent.\n* Temporomandibular disorders\n* Smoking of more than 10 cigarettes per day\n* Untreated caries or periodontal disease of remaining dentition",true,"60 Years",{"count":78,"type":22},40,[25],"To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant.\n\nTo assess whether the new form of multilayered zirconia crowns will show similar survival and success rate to conventional monolithic Zirconia screw-retained to implants in molar and premolar regions.\n\nFirst Null Hypothesis: Multilayered monolithic zirconia crowns would have similar survival, success rate compared to conventional monolithic zirconia implant supported crowns.\n\nSecond Null hypothesis: There would be no difference in clinical and patients related outcomes between multilayered and conventional monolithic zirconia implant supported crowns.",[29,82],"Dental Implant",[84,85,86,87,88],"implant-supported","patient-reported outcome,","technical, biological outcomes","survival\u002Fsuccess rate","single-tooth restorations","2025-03-26",{"date":91,"type":35},"2025-04-01",{"date":93,"type":22},"2025-08",{"date":95,"type":22},"2026-11",{"name":97,"class":42},"University of Jordan",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":75,"sex":17,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":4,"studyType":23,"phases":109,"briefSummary":110,"conditions":111,"keywords":112,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":67},"100550670","comparative-clinical-evaluation-of-bioflx-zirconia-and-stainless-steel-crowns-in-primary-molars-100550670","NCT06450093","Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars","Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Children who are free from any systemic disease.\n* Children with a carious lower primary molar indicated for crown restoration.\n* Teeth with an intact antagonist and neighboring primary molar.\n* Cooperative children with scores 1 and 2 (positive or definitely positive) according to Frankl's behavior rating scale.\n\nExclusion Criteria:\n\n* Children with extremely poor oral hygiene.\n* Teeth showing radiographical furcation involvement or root resorption.\n* Children with para-functional habits, bruxism, or deep bite.\n* Teeth with inadequate non-restorable crown structure.","4 Years","7 Years",{"count":108,"type":22},51,[25],"This study will be conducted to:\n\nEvaluate and compare the clinical success, periodontal changes, and wear of antagonist teeth for three types of prefabricated crowns in primary molars: BioFlx crowns, Zirconia crowns, and Stainless Steel crowns.",[29],[113,114,115,116,117],"Bioflx Crowns","Wear","Zirconia Crowns","stainless steel Crowns","periodontal changes","2024-06-06",{"date":120,"type":35},"2024-06-10",{"date":122,"type":35},"2024-04-04",{"date":124,"type":22},"2026-06-01",{"name":126,"class":42},"Mansoura University"]