[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dentin-caries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dentin-caries":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,75,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100642394","pmcf-study-on-the-performance-and-safety-of-on-dent-pmma-discsblocks-and-resin-products-for-temporary-restorations-100642394",false,"NCT07632443","PMCF Study on The Performance and Safety of ON DENT® PMMA Discs\u002FBlocks and Resin Products for Temporary Restorations","Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Performance and Safety of ON DENT™ PMMA Disc\u002FBlock and Resin Products Used in Temporary Restoration Fabrication","Inclusion Criteria:\n\n* Aged 18 years or older\n* Male or female\n* Requires 1\u002F2\u002F3-unit prosthetic restoration with temporary crown or bridge\n* No active periodontal disease\n* No general health condition contraindicated to treatment\n* Not legally restricted (no military conscription, incarceration, or other legal restriction)\n* Provision of signed informed consent form\n\nExclusion Criteria:\n\n* Suspected or confirmed pregnancy,\n* Temporomandibular joint disorder or limited mouth opening\n* Deep subgingival margins (\\>0.5 mm)\n* Non-restorable teeth\n* Non-functional teeth (no opposing counterpart \u002Fantagonist)\n* Probing depth \\>3 mm\n* Pathological tooth mobility\n* Unfavorable occlusal relationship or parafunction (bruxism, etc.)\n* Active systemic infection or condition\u002Ftreatment that may impede treatment (radiotherapy, bisphosphonate use, etc.)\n* Inadequate oral hygiene or cognitive\u002Fphysical disorders impairing daily self-care maintenance.\n* Uncontrolled alcohol, tobacco, or nicotine product use\n* History of allergy or hypersensitivity to PMMA or resin components\n* Concurrent participation in another interventional clinical study","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the clinical performance and safety of temporary crown and bridge restorations fabricated using CE-marked ON DENT™ restorative materials throughout their functional intraoral clinical duration. A total of 120 adult patients requiring fixed prosthodontic treatments will be randomly assigned to four independent parallel groups (30 patients per group) based on the specific type of temporary material utilized: Tempo-CAD Monocolor PMMA, Tempo-CAD Monocolor SHT PMMA, Tempo-CAD Multicolor SHT PMMA, or Print On Cyclone Perma liquid resin. Patients will be monitored closely across 5 clinical visits up to a maximum duration of 6 months to assess prosthodontic survival, success rates, biological adaptations, and patient-reported quality of life outcomes.",[26,27,28],"Tooth Loss","Dentin Caries","Tooth Fractures",[30,31,32,33,34,35,36,37,38],"Post-Market Clinical Follow-Up (PMCF)","Temporary Dental Restoration","Dental Prosthetics","Temporary Crown","Temporary Bridge","PMMA","Dental Resin","CAD\u002FCAM Dentistry","Revised FDI Criteria","RECRUITING","2026-06-07",{"date":42,"type":43},"2026-06-10","ACTUAL",{"date":45,"type":43},"2025-12-05",{"date":47,"type":20},"2027-07-04",{"name":49,"class":50},"On Dent Tibbi Malzeme Dis Protez Ith. ve Ihr. San. Ltd. Sti.","INDUSTRY",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":60,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":51},"100619317","evaluation-of-the-effect-of-flowable-composites-on-postoperative-sensitivity-in-class-i-restorations-100619317","NCT07343050","Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.","Evaluation of Dental Restorations","Inclusion Criteria:\n\n* good general health\n* no heart disease\n* no diabetes\n* no systemic diseases such as hypertension\n\nExclusion Criteria:\n\n* Patients with advanced periodontitis and associated postoperative sensitivity,\n* Pregnant and breastfeeding women,\n* Patients undergoing orthodontic treatment,\n* Patients using appliances,\n* Patients with direct pulp capping",true,{"count":19,"type":20},"24 Months","OBSERVATIONAL","The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up. The hypothesis to be tested in this study is that the type of composite material will not affect clinical success.",[27],"2026-01-06",{"date":67,"type":43},"2026-01-15",{"date":69,"type":43},"2025-05-16",{"date":71,"type":20},"2027-08-01",{"name":73,"class":74},"Recep Tayyip Erdogan University","OTHER",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":85,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":88,"locationsCount":51},"100619318","evaluation-of-the-clinical-performance-of-different-composite-materials-in-class-iii-and-iv-restorations-100619318","NCT07343063","Evaluation of the Clinical Performance of Different Composite Materials in Class III and IV Restorations.","Evaluation of Anterior Restorations","Inclusion Criteria:\n\n* Good general health\n* No heart disease,\n* No diabetes\n* No systemic diseases such as hypertension\n\nExclusion Criteria:\n\n* Individuals with advanced periodontitis and associated postoperative sensitivity\n* Pregnant and breastfeeding women\n* Individuals undergoing orthodontic treatment and using appliances\n* Individuals with direct pulp capping\n* Individuals with bruxism",{"count":19,"type":20},"In this study, a universal adhesive was used with different adhesive techniques (self-etch and total-etch modes) and evaluated for 18 months in three different types of composite material class III and class IV restorations according to the FDI criteria. The hypotheses tested in this study are: (1) clinical success will not differ between different composite materials and (2) clinical outcomes will not differ between different application modes of the universal adhesive.",[27],{"date":67,"type":43},{"date":69,"type":43},{"date":71,"type":20},{"name":73,"class":74},{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":59,"sex":16,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":21,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":108,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":4},"100597962","early-phase-1-clinical-performance-and-remineralization-potential-of-self--assembling-peptide-p11-4-containing-fluoride-versus-er-cr-ysgg-laser-treatment-and-micro-tensile-bond-strength-of-giomer-restoration-in-carious-lesions-100597962","NCT07065305","Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions","Inclusion Criteria:\n\n* o Patients aged (20 - 40) years.\n\n  * Presence of at least one posterior permanent molar with an occlusal carious lesion classified as ICDAS code 3 or 4 requiring operative treatment.\n  * Good general and oral health.\n  * Willingness to participate and provide informed consent.\n\nExclusion Criteria:\n\n* o Patients with systemic conditions affecting oral health or healing.\n\n  * Teeth with pulp involvement or periapical pathology.\n  * Allergy to study materials.\n  * Poor oral hygiene or periodontal disease in the target tooth region.","20 Years","40 Years",{"count":98,"type":20},21,[100],"EARLY_PHASE1","This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated caries-affected dentin and the influence of Er, Cr: YSGG Laser treatment.",[103,27],"Remineralization Potential",[105,106,103,107],"Er, Cr: YSGG Laser","Caries-Affected Dentin","Self-Assembling Peptide P11-4 Containing Fluoride","NOT_YET_RECRUITING","2025-07-24",{"date":111,"type":43},"2025-07-29",{"date":113,"type":20},"2025-09-15",{"date":115,"type":20},"2026-09-15",{"name":117,"class":74},"Al-Azhar University"]