[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dentin-sensitivity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dentin-sensitivity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,70,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100616048","real-world-study-of-a-calcium-sodium-phosphosilicate-anti-sensitivity-toothpaste-for-dentin-hypersensitivity-relief-100616048",false,"NCT07300540","Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief","A Real-World Evidence Study Evaluating Oral Health Related Quality of Life With Use of a Calcium Sodium Phosphosilicate Anti-Sensitivity Dentifrice for Dentin Hypersensitivity Management","Inclusion Criteria:\n\n* Participant who has provided consent indicating they have been informed of all pertinent aspects of the study.\n* All genders who, at the time of screening, are aged 18 to 65.\n* Participant who is able to independently complete all activities on their smart devices\n* Participant who has tooth sensitivity (self-reported symptoms).\n\nExclusion Criteria:\n\n* Participants whose tooth sensitivity could be caused by other factors or clinical pathology than DH, as self-reported on the screening questionnaire, which include:\n\n  1. Participant who has been\u002Fis on multiple prescription medications to treat severe acid reflux on a regular basis or has had surgery for acid reflux.\n  2. Participant with full or partial denture.\n  3. Participant who has undergone treatment for periodontal or gum disease within 6 months of screening or is currently undergoing treatment for periodontal or gum disease.\n  4. Participant who has been informed by a Dental Health Care Professional (DHCP) that they have active periodontitis.\n  5. Participants who have been informed by a DHCP that they have active caries.\n  6. Participant with any chronic and\u002For severe painful health condition which lead to regular use of pain relief medications (more than 3 days a week).\n* Participant with known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients.",true,"ALL","18 Years","65 Years",{"count":21,"type":22},500,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim of this study is to evaluate the impact of a commercially available desensitizing dentifrice containing 5 percent (%) Calcium sodium phosphosilicate (CSPS) on oral health related quality of life (OHrQoL) in a DH (Dentin Hypersensitivity) population in a real-world setting.",[28],"Dentin Sensitivity","RECRUITING","2026-03-09",{"date":32,"type":33},"2026-03-11","ACTUAL",{"date":35,"type":33},"2026-03-04",{"date":37,"type":22},"2026-11",{"name":39,"class":40},"HALEON","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":52,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100595062","phase-1-effect-of-an-experimental-cannabidiol-gel-on-tooth-sensitivity-100595062","NCT07027566","Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity","Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity Induced by Tooth Bleaching","Inclusion Criteria:\n\n* Participants must have at least 28 teeth in the cavity\n* Good oral and general health\n\nExclusion Criteria:\n\n* active caries or periodontal disease\n* visible cracks in front teeth upper or lower\n* with evident malocclusion\n* restorations and prosthetics in teeth anterior teeth\n* gastroesophageal disorders\n* severe internal tooth discoloration (tetracycline , fluorosis or pulped teeth)\n* dentin exposure in anterior teeth and \u002For later\n* parafunctional habits\n* tooth sensitivity\n* whitening treatment prior to or undergoing orthodontic treatment\n* Furthermore, smokers, pregnant or breastfeeding women do not will be included.","40 Years",{"count":51,"type":22},75,[53],"PHASE1","The goal of this clinical trial will be to evaluate the effect applying an experimental gel based on cannabidiol oil (CBD) on tooth sensitivity induced by tooth bleaching with 35% hydrogen peroxide (HP). Volunteers will be selected and allocated to the following groups: GP - placebo gel, GCBD - experimental cannabidiol gel and GKF - Potassium Nitrate and Sodium Fluoride Gel. In each group, the corresponding desensitizing gel will be applied to on the teeth for 10 minutes. All groups will then undergo in-office whitening treatment with 35% hydrogen peroxide. Patients will be instructed to record tooth sensitivity on a daily basis during the 21 days of follow-up. Pain intensity will be measured using a visual analog scale (VAS), while the risk of developing sensitivity will be recorded after each session of the whitening procedure, with two response option.",[28],[57,58,28],"Tooth Bleaching","Cannabidiol","NOT_YET_RECRUITING","2025-06-10",{"date":62,"type":33},"2025-06-18",{"date":64,"type":22},"2025-07-25",{"date":66,"type":22},"2026-07",{"name":68,"class":69},"Universidade Federal do Para","OTHER",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":77,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":41},"100577770","efficacy-and-safety-assessment-of-experimental-bleaching-agents-100577770","NCT06802614","Efficacy and Safety Assessment of Experimental Bleaching Agents","A Randomized Controlled Clinical Trial Comparing the Efficacy of Two Experimental Bleaching Gels With and Without Nanoparticles and Light Irradiation Versus Whiteness HP 35% and Whiteness HP AutoMixx 6% in Patients With A2-C4 Tooth Discolorations","Inclusion Criteria:\n\n* Age: 18-65 years old.\n* Healthy periodontal tissues.\n* Willingness to participate and follow the post-treatment protocols.\n* Ability to provide informed consent.\n* Teeth having baseline colors ranging from shade A2 to C4\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women.\n* Teeth with restorations.\n* History of dentin hypersensitivity.\n* Active caries, periodontal disease or endodontically treated teeth.\n* Use of substances that could affect tooth color during the trial, such as smoking and vaping.",{"count":78,"type":22},240,[25],"Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial bleaching products of low and high concentrations. The objective is to evaluate tooth color change, sensitivity, and patient satisfaction in patients with moderate yellowing of their teeth. Methods: This is a randomized controlled trial that will include 120 participants aged 18-65 years. Participants will be randomly assigned to one of 12 treatment groups: Gel A (with or without nanoparticles, with or without light), Gel B (with or without nanoparticles, with or without light), Whiteness HP 35% (with or without light) and Whiteness Automixx 6% (with or without light). The primary outcome is tooth color change, measured using a commercially-available equipment. Secondary outcomes will include tooth sensitivity and patient satisfaction. Randomization will be computer-generated. Results: The study is expected to show differences in color change between the experimental and commercial gels. Tooth sensitivity and patient satisfaction will be evaluated to determine the overall effectiveness and safety of the treatments. Conclusions: This trial will provide information into the whitening efficacy of two experimental gels compared to two widely used commercial products.",[82,28,83],"Tooth Discoloration","Patient Satisfaction",[85,86,87,88],"Tooth Whitenining","Dental Bleaching","Hydrogen Peroxide","Titanium Dioxide Nanoparticles","2025-01-24",{"date":91,"type":33},"2025-01-31",{"date":93,"type":22},"2025-03-01",{"date":95,"type":22},"2025-09-30",{"name":97,"class":69},"University of Oklahoma",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":16,"sex":17,"minAge":105,"maxAge":19,"enrollmentInfo":106,"targetDuration":4,"studyType":23,"phases":108,"briefSummary":109,"conditions":110,"keywords":113,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":41},"100551734","a-clinical-trial-to-compare-lasotronix-alone-or-in-combination-with-cpp-acp-to-treat-dh-100551734","NCT06463938","A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH","A Clinical Study to Evaluate the Effectiveness of Casein Phosphopeptide, Amorphous Calcium Phosphate Paste (CPP-ACP) Used Alone or in Combination With Lasotronix (Diode Laser) to Treat Dentin Hypersensitivity","Inclusion criteria:\n\n* Patients of either gender, with ages between 25-65 years\n* should have at least more than one hypersensitive and vital tooth without any carious lesion or defective restoration\n\nExclusion criteria:\n\n* History of desensitizing therapy on the affected tooth\u002Fteeth in last six months (use of desensitizing toothpaste)\n* use of antibiotics \u002Fanalgesic\u002Fanti-inflammatory drugs\n* history of smoking\n* pregnancy\n* those who are not willing to participate or give follow-ups","25 Years",{"count":107,"type":22},120,[25],"Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects\". DH has a prevalence rate ranging from 1.3% to 92.1%, commonly affecting old ages. The use of laser has opened new dimensions in the treatment of DH. To the author's knowledge, not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP. Therefore, this research aims to determine the effectiveness of Casein phospho peptide paste (CPP-ACP) used alone or combined with a diode laser (LASOTRONIX).",[28,111,112],"Hypersensitivity","Cervical Lesion",[28,114,115],"Lasotronix","Diode laser","2024-07-25",{"date":118,"type":33},"2024-07-26",{"date":120,"type":33},"2024-05-12",{"date":122,"type":22},"2024-10-10",{"name":124,"class":69},"Dow University of Health Sciences"]