[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"denture-retention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:denture-retention":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100631091","a-clinical-study-to-assess-the-effectiveness-of-use-of-three-experimental-denture-adhesives-compared-to-using-no-adhesive-100631091",false,"NCT07496164","A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive","A Randomized, Controlled, Single-Blind, Cross Over Clinical Study Assessing the Maximum Maxillary Bite Force When Using Three Denture Adhesives Compared to Using No-Adhesive","Inclusion Criteria:\n\n* Participant provision of a signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed.\n* A male or female participant who, at the time of screening, is aged 18+ years.\n* A participant who is willing and able to comply with scheduled visits, and other study procedures.\n* A participant in good general and mental health with, in the opinion of the investigator or medically qualified designee, no clinically significant or relevant abnormalities in medical history or upon oral examination, or condition, that would impact the participant's safety, wellbeing or the outcome of the study, if they were to participate in the study, or affect the individual's ability to understand and follow study procedures and requirements.\n* A participant with a completely edentulous maxillary arch restored with a conventional maxillary full denture with an acrylic base.\n* A participant who is dentate in the mandibular arch or has a partial or full denture in the mandibular arch that is:\n\n  1. sufficiently stable, in the opinion of the investigator, to enable the bite force determination to be performed.\n  2. well made (according to the well-made assessment).\n\nExclusion Criteria:\n\n* A participant who is an employee of the investigational site, either directly involved in the conduct of the study or a member of their immediate family; or an employee of the investigational site otherwise supervised by the investigator; or a Haleon employee directly involved in the conduct of the study or a member of their immediate family.\n* A participant who has participated in other studies (including non-medicinal studies) involving investigational product(s) within 30 days prior to Visit 1 and\u002For during study participation.\n* A participant who is pregnant (self-reported) or intending to become pregnant or who is breastfeeding over the duration of the study.\n* A participant with known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients.\n* A participant unwilling or unable to comply with the Lifestyle Considerations described in this protocol.\n* A participant who is currently taking or has taken a bisphosphonate drug.\n* A participant who uses any medication or has a condition that, in the opinion of the investigator, would interfere with the conduct of the study.\n* A participant with a recent history (within the last year) of alcohol or other substance abuse.\n* A participant who has previously been enrolled in this study.\n* A participant who, in the opinion of the investigator, is unable to comply with study requirements and\u002For who is not able to reliably perform a valid bite.\n* A participant who, in the opinion of the investigator or medically qualified designee, should not participate in the study.",true,"ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the proposed clinical study is to investigate the efficacy of three experimental denture adhesive creams to improve denture hold over a period of 13 hours.",[27],"Denture Retention","RECRUITING","2026-04-06",{"date":31,"type":32},"2026-04-09","ACTUAL",{"date":34,"type":32},"2026-03-30",{"date":36,"type":21},"2026-11",{"name":38,"class":39},"HALEON","INDUSTRY",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100554325","comparing-impression-techniques-for-maxillary-complete-denture-retention-100554325","NCT06497621","Comparing Impression Techniques for Maxillary Complete Denture Retention","Effect of Two Impression Techniques on Retention of Maxillary Complete Denture in Pakistani Population: A Double-blinded Crossover Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients with mild to moderately resorbed maxillary alveolar ridge\n* Patients with bimaxillary edentulous arches\n* Patients aged between 35 to 85 years willing to participate in the study\n* Patients who could be available for follow up visits\n\nExclusion Criteria:\n\n* Patients with palatal torus or bony exostoses or severe undercuts in the maxillary arch\n* Patients with uncontrolled diabetes, osteoporosis, osteomalacia and osteopenia\n* Patients with xerostomia\n* Patients with mucosa covering the denture bearing area with signs of inflammation, ulceration, or hyperplasia.\n* Patients undergoing radiotherapy or chemotherapy or maxillofacial surgery\n* Patients suffering from maxillofacial trauma\n* Patients with neuromuscular disorders\n* Patients with clinical signs and symptoms of temporomandibular joint dysfunction\n* Patients with highly resorbed maxillary ridge and\u002F or flabby ridge\n* Patient with hypersensitivity to silicone materials","35 Years","80 Years",{"count":51,"type":21},35,[24],"The primary objective of this protocol is to compare retention in maxillary complete dentures using single-versus two-step Poly-vinyl Siloxane (PVS) impressions in edentulous patients at denture delivery. Secondary objectives include assessing patient satisfaction with impression methods and denture satisfaction after a two-month adaptation and comparing post-delivery adjustment visits.",[27,55],"Patient Satisfaction",[57,58,59,60],"Crossover","Complete Denture","Retention","Poly-vinyl siloxane","NOT_YET_RECRUITING","2024-07-04",{"date":64,"type":32},"2024-07-12",{"date":66,"type":21},"2025-07-01",{"date":68,"type":21},"2027-03-31",{"name":70,"class":71},"Aga Khan University","OTHER"]