[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"depression-and-anxiety-symptom\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:depression-and-anxiety-symptom":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100543002","machine-learning-based-classification-of-symptom-clusters-and-online-cbt-100543002",false,"NCT06350201","Machine Learning-based Classification of Symptom Clusters and Online CBT","Machine Learning-based Classification of Symptom Clusters and Matched Online Cognitive Behavior Intervention for Depression Symptom and Anxiety Symptom","Inclusion Criteria:\n\n* Aged between 18 and 64 years. PHQ-9 ≥10 and\u002For GAD-7 ≥8 at baseline assessment defined as the threshold for caseness.\n\nExclusion Criteria:\n\n* People will be excluded if they meet any of the following criteria:\n\n  1. They are receiving psychological therapy during an interview for any mental health issue;\n  2. currently acutely suicidal or have attempted suicide in the past 2 months, as indicated by PHQ-9 item 9;\n  3. cognitively impaired or diagnosed with bipolar disorder or psychosis or experiencing psychotic symptoms; d) dependent on alcohol or drugs; e) living with an unstable or acute medical illness that would interfere with trial participation.","ALL","18 Years","64 Years",{"count":20,"type":21},380,"ESTIMATED","INTERVENTIONAL",[24],"NA","To breakthrough the bottleneck identified, we will conduct a cross-sectional study to develop a symptom clustering model for depression and anxiety. A wide range of statistical methods as well as machine learning approaches were explored, and a cohesive hierarchical clustering algorithm will be used. After developing the model, a symptom-matched intervention program based on problem solving therapy will be formulated. We are supposed to examine whether its use for personalizing symptom-matched psychological treatment can lead to improved patient outcomes, compared with usual care. This project is expected to provide a new and precise method for the emotion management, which will provide a standardized intervention pathway combining screening with treatment for the management of depression symptom and anxiety symptom. A preciser intervention matched to individual symptoms may provide important insight in improving patient outcome as well as a standardized mood management pathway targeting to the early detection and intervention for community residents.",[27],"Depression and Anxiety Symptom",[29,30,31,32,33],"machine learning approach","CBT","PST","depression","anxiety","RECRUITING","2026-05-07",{"date":37,"type":38},"2026-05-12","ACTUAL",{"date":40,"type":38},"2025-09-01",{"date":42,"type":21},"2026-12-01",{"name":44,"class":45},"Wuhan Mental Health Centre","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":67,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":46},"100624916","the-effect-of-a-four-week-hatha-yoga-intervention-to-improve-quality-of-life-anxiety-and-depressive-symptoms-in-individuals-undergoing-assisted-reproductive-technology-art-treatment-100624916","NCT07415850","The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment","The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 18 years of age or older\n* Understand English\n* Scheduled for or currently undergoing an IVF cycle\n* Access to smartphone\u002Fcomputer\u002Ftablet and internet\n* Have a valid working email address\n\nExclusion Criteria:\n\n* Individuals who are Pregnant, or who become Pregnant during the study\n* Individuals undergoing non-IVF cycles (i.e. intrauterine insemination)\n* Individuals undergoing a frozen embryo transfer (FET) cycle\n* Individuals who are currently regularly practicing yoga\n* Individuals who score in the \"severe depression\" classification on the PHQ-9 (PHQ-9 score of 20-27)\n* Individuals endorsing suicidal ideation (answering yes on #9 of PHQ-9).","FEMALE",{"count":56,"type":21},80,[24],"The goal of this clinical trial is to learn if a four-week yoga program works to improve quality of life in people undergoing IVF (In Vitro Fertilization). It will also learn if a four-week yoga program decreases anxiety and depression symptoms in people undergoing IVF.\n\nThe main questions it aims to answer are:\n\n* Does a four-week yoga program effect quality of life, anxiety, and depression symptoms in people undergoing IVF?\n* Do the effects vary by individual characteristics of the people in the study?\n\nResearchers will compare the yoga intervention group to routine care as usual.\n\nParticipants will:\n\n* Participate in a weekly virtual yoga class for four weeks (total of four yoga classes), or follow routine care as usual while undergoing IVF.\n* Take three online surveys every 4 weeks.\n* Be involved in the study for 8 weeks.",[60,61,62,63,27,64,65,66],"IVF","In Vitro Fertilization","Quality of Life (QOL)","Anxiety","Assisted Reproduction Technologies","Yoga","Mental Health",[68,69,70,71,65,72,73],"Fertilization in Vitro","Reproductive Techniques, Assisted","Quality of Life","Psychological Well-Being","Mind-Body Therapies","Complementary Therapies","NOT_YET_RECRUITING","2026-02-09",{"date":77,"type":38},"2026-02-17",{"date":79,"type":21},"2026-01-21",{"date":81,"type":21},"2027-01-31",{"name":83,"class":45},"Villanova University",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":46},"100623046","icbt-for-psychological-symptoms-related-to-economy-100623046","NCT07391540","ICBT for Psychological Symptoms Related to Economy","Ekorostudien - Internet-based Cognitive Behavioral Therapy for Psychological Symptoms Related to Economy","Inclusion Criteria:\n\n* Experience mild to moderate psychological symptoms or problems related to economy\n* 18 years or older\n* Ability to speak, read and write in Swedish\n* Have access to the internet and a smartphone, computer or other device\n\nExclusion Criteria:\n\n* Severe psychiatric or somatic illness that makes participation harder or impossible\n* Ongoing addiction\n* Acute suicidality\n* Other ongoing psychological treatment\n* Recent (within the latest month) changes in the dose of psychotropic medication or planned change of dose during the treatment weeks",{"count":92,"type":21},50,[24],"This study aims to investigate the effects of guided internet-based cogitive behavioral therapy (ICBT) on psychological symptoms related to economy. In this pilot study, the investigators investigate participants' psychological symptoms before and after, and one and two years after, they have received eight weeks of therapist guided ICBT.",[27],[97,98,99,100],"Internet-based cognitive behavioral therapy (ICBT)","Psychological treatment","Economy","Depression","2026-02-02",{"date":103,"type":38},"2026-02-06",{"date":105,"type":38},"2026-01-14",{"date":107,"type":21},"2028-05-31",{"name":109,"class":110},"Linkoeping University","OTHER_GOV"]