[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dermatomyositis-with-calcinosis-cutis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dermatomyositis-with-calcinosis-cutis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100595824","photoacousticultrasound-imaging-in-patients-of-dermatomyositis-with-calcinosis-cutis-characteristic-findings-and-treatment-response-evaluation-100595824",false,"NCT07037472","Photoacoustic\u002FUltrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response Evaluation","A Cohort Study Establishing a Standardized Scoring System in Dermatomyositis With Calcinosis Cutis and Assessing Treatment Response Via Multimodal Photoacoustic-Ultrasound Imaging","Inclusion Criteria:\n\n* All patients fulfilled the 2017 EULAR\u002FACR classification criteria for idiopathic inflammatory myositis. Of the adult DM patients enrolled, those were found to have calcinosis and were subsequently included in our analysis.\n* Among enrollees with idiopathic inflammatory myositis, patients with pathognomonic skin rashes were subclassified as DM or amyopathic DM patients based on the 2017 EULAR\u002FACR classification tree.\n* For patients without pathognomonic skin manifestations, DM was defined according to muscle biopsy.\n* Patients with amyopathic DM were grouped with DM patients.\n* Calcinosis diagnosis was based on clinical examination findings.\n\nExclusion Criteria:\n\n* Patients whose age at disease onset was \\\u003C18 years and those with overlap syndrome and\u002For IBM were excluded.","ALL","18 Years","80 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Photoacoustic imaging (PAI) is an emerging biomedical modality that integrates the advantages of optical contrast and ultrasound imaging depth. Capable of providing morphological, functional, and molecular information, PAI shows significant promise for visualizing human superficial tissue. The goal of this clinical trial is to build a PAI evaluation method for DM skin lesions, explore its application value in assessing DM disease severity and evaluation of treatment response. The main questions it aims to answer are:\n\n1. How to establish a non-invasive PA\u002FUS imaging evaluation method for DM skin lesions?\n2. Can PAI precisely assess DM disease severity?\n3. Can PAI systems predict the treatment response in DM with calcinosis cutis? Participants will receive regular PA\u002FUS imaging examinations during five stages of treatment (before treatment, 3 months, 6 months, 9 months and 12 months). And the effectiveness of PA\u002FUS in treatment response for DM at different time points will be evaluated.",[27,28],"Dermatomyositis","Dermatomyositis With Calcinosis Cutis",[27,30,31],"Dermatomyositis with Calcinosis cutis","Photoacoustic imaging","RECRUITING","2025-06-16",{"date":35,"type":36},"2025-06-25","ACTUAL",{"date":38,"type":36},"2024-01-01",{"date":40,"type":21},"2028-12-31",{"name":42,"class":43},"Peking Union Medical College Hospital","OTHER"]