[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"developmental-dysplasia-of-the-hip\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:developmental-dysplasia-of-the-hip":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,53,83,109,135,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100637695","computer-assisted-comparison-of-hip-socket-volume-and-surface-shape-after-pediatric-acetabular-osteotomies-100637695",false,"NCT07581717","Computer-Assisted Comparison of Hip Socket Volume and Surface Shape After Pediatric Acetabular Osteotomies","Computer-Assisted Comparative Analysis of Acetabular Volume and Surface Morphology in Pediatric Acetabular Osteotomies (Salter, Dega, San Diego, and Pemberton)","PAVMS","Inclusion Criteria:\n\n1. Age 2 to 18 years\n2. Developmental dysplasia of the hip or residual acetabular dysplasia\n3. Primary Salter, Dega, San Diego, or Pemberton acetabular osteotomy planned at Istanbul University, Istanbul Faculty of Medicine\n4. Preoperative hip MRI available within 6 weeks before surgery\n5. Early postoperative hip MRI available 3 to 8 weeks after surgery\n6. MRI quality adequate for three-dimensional morphometric analysis\n7. Unilateral or bilateral cases eligible\n\nExclusion Criteria:\n\n1. Hip pathology not related to developmental dysplasia of the hip, including Perthes disease, slipped capital femoral epiphysis, neuromuscular dysplasia, or infection\u002Ftrauma sequelae\n2. Previous surgery on the same hip that significantly alters anatomy, including prior pelvic or femoral osteotomy or open reduction, or current metal implant\u002Ffusion\n3. MRI contraindication or safety issue, including MR-incompatible implant\u002Fdevice, severe claustrophobia, or a medical barrier to sedation\u002Fanesthesia\n4. MRI not compatible with protocol or inadequate for analysis","ALL","2 Years","18 Years",{"count":21,"type":22},12,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn how four acetabular osteotomy techniques change the shape of the hip socket in children and adolescents with developmental dysplasia of the hip or residual acetabular dysplasia.\n\nThe main questions it aims to answer are:\n\nHow do virtual Salter, Dega, San Diego, and Pemberton osteotomies differ in acetabular volume and surface shape on participant-specific three-dimensional models? How closely does the virtual result of the osteotomy actually performed match the early postoperative magnetic resonance imaging (MRI)?\n\nParticipants will have a three-dimensional pelvis-acetabulum model created from preoperative MRI. Researchers will perform virtual Salter, Dega, San Diego, and Pemberton osteotomies on that model and measure the resulting acetabular morphology. The virtual result of the osteotomy actually performed will then be compared with the participant's early postoperative MRI.",[26,27,28],"Developmental Dysplasia of the Hip (DDH)","Developmental Dysplasia of the Hip","Acetabular Dysplasia",[30,31,32,33,34,35,36,37,38,39],"Salter osteotomy","Dega osteotomy","San Diego osteotomy","Pemberton osteotomy","Developmental dysplasia of the hip","Acetabular dysplasia","Magnetic resonance imaging","Three dimensional modeling","Acetabular morphometry","Methodological validation","RECRUITING","2026-06-24",{"date":43,"type":44},"2026-06-26","ACTUAL",{"date":46,"type":44},"2026-05-10",{"date":48,"type":22},"2026-10-15",{"name":50,"class":51},"Istanbul University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":52},"100294025","early-phase-1-intraoperative-contrast-enhanced-ultrasound-evaluation-of-blood-flow-at-the-time-of-surgical-hip-reduction-for-ddh-100294025","NCT03107520","Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH","Use of Intraoperative Contrast-enhanced Ultrasound to Evaluate Femoral Head Perfusion in Infants With Developmental Dysplasia of the Hip at the Time of Surgical Reduction","Inclusion Criteria:\n\n* Males or females between 4 months and up to and including 24 months of age at the time of surgery.\n* Diagnosed with DDH.\n* Failed conservative treatment, or present with late-diagnosed DDH (where conservative treatment would not be appropriate to initiate at their age), and are undergoing closed or open reduction and spica casting.\n* Informed consent (parental permission)\n\nExclusion Criteria:\n\n* \\> 24 months of age at the time of surgery.\n* Subjects with DDH who are successfully treated with conservative measures and do not require surgical reduction.\n* Previous open hip reduction of the affected side\n* Children with known complex congenital heart disease or unstable cardiopulmonary conditions (as noted in the package labeling for Lumason) including acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure or serious ventricular arrhythmias will be excluded.\n* History of allergic reaction to Lumason, sulfur hexafluoride, sulfur hexafluoride lipid microsphere components, or other ingredients in Lumason (polyethylene glycol, distearoylphosphatidylcholine (DSPC), dipalmitoylphosphatidylglycerol sodium (DPPG-Ns), palmitic acid).Parental\u002Fguardian permission (informed consent) and if appropriate, child assent.","4 Months","24 Months",{"count":63,"type":22},125,"INTERVENTIONAL",[66],"EARLY_PHASE1","This study evaluates the feasibility and utility of contrast-enhanced ultrasound to provide real-time assessment of blood flow to the femoral head in infants undergoing surgical reduction for developmental dysplasia of the hip.",[27],[70,71,72,73],"contrast-enhanced ultrasound","Lumason","developmental dysplasia of the hip (DDH)","avascular necrosis","2026-04-13",{"date":76,"type":44},"2026-04-15",{"date":78,"type":44},"2017-05-22",{"date":80,"type":22},"2030-04",{"name":82,"class":51},"Children's Hospital of Philadelphia",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":64,"phases":93,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":4},"100630905","hip-arthroscopy-versus-conservative-treatment-for-borderline-hip-dysplasia-100630905","NCT07493746","Hip Arthroscopy Versus Conservative Treatment for Borderline Hip Dysplasia","Arthroscopic Hip Surgery Versus Individualized Conservative Treatment for Borderline Hip Dysplasia: A Multicenter Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age 18-42 years (studies have reported age ≥42 years as a risk factor for hip arthroscopy in BDDH: HR=11.6, 95% CI: 2.5-53.9), either sex;\n2. Symptoms (anterior-lateral groin, lateral, or posterolateral hip pain or discomfort), physical examination findings (limp, clicking, locking, and limited range of motion), and imaging findings consistent with BDDH diagnosis (standing anteroposterior pelvic radiograph with Wiberg lateral center-edge angle \\[LCEA\\] 18-25°);\n3. Surgeon's assessment that the patient with BDDH will benefit from hip arthroscopy or conservative treatment;\n4. Full understanding of trial benefits and risks, willingness to participate in the intervention and complete follow-up, and signed informed consent.\n\nExclusion Criteria:\n\n1. Standing anteroposterior pelvic radiograph showing Tönnis grade ≥2 and\u002For joint space \\\u003C2 mm;\n2. Standing anteroposterior pelvic radiograph showing FEAR index \\>5°;\n3. Positive physical examination for joint instability: anterior apprehension test (HEER test), abduction-extension-external rotation test in lateral decubitus position (AB-HEER test), or prone external rotation test;\n4. History of high-energy hip trauma, previous ipsilateral or contralateral hip surgery, avascular necrosis of the femoral head, slipped capital femoral epiphysis, Perthes disease, severe osteoporosis, tumor, acetabular stress fracture, or hypertrophic or inflammatory hip disease;\n5. Concomitant consciousness disorder, psychiatric illness, or neuromuscular dysfunction affecting lower limb function;\n6. Contraindications to hip arthroscopy (such as systemic or local infection).","42 Years",{"count":92,"type":22},248,[94],"NA","The goal of this clinical trial is to compare the efficacy of hip arthroscopy versus individualized conservative treatment in patients with borderline developmental dysplasia of the hip (BDDH), defined by a lateral center-edge angle (LCEA) of 18-25°. The main question it aims to answer is: which treatment approach, surgical or conservative, provides superior pain relief, functional recovery, and quality of life improvement at 12 and 24 months post randomization? Participants will be randomly assigned (1:1) to either standardized hip arthroscopy, comprising capsular management, acetabular rim limited trimming, labral repair, and Cam deformity correction when indicated; or a 3-month individualized conservative protocol including patient education, nonsteroidal anti-inflammatory drugs (NSAIDs) for 2-4 weeks, chondroprotective supplementation for 8 weeks, and supervised progressive exercise training. All participants will undergo follow-up assessments at baseline, 12, and 24 months. The primary outcome is the modified Harris Hip Score (mHHS). Secondary outcomes include patient-reported outcome measures (VAS pain, iHOT-12, SF-12, and patient satisfaction), clinical assessments, and safety monitoring.",[27],[98],"Borderline hip dysplasia; Arthroscopy; Conservative treatment","NOT_YET_RECRUITING","2026-03-20",{"date":102,"type":44},"2026-03-25",{"date":104,"type":22},"2026-06-01",{"date":106,"type":22},"2029-06-30",{"name":108,"class":51},"ChunBao Li",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":17,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":64,"phases":121,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":52},"100622571","caudal-dexmedetomidine-vs-ketamine-for-postoperative-analgesia-in-pediatric-ddh-surgery-100622571","NCT07385352","Caudal Dexmedetomidine vs Ketamine for Postoperative Analgesia in Pediatric DDH Surgery","Comparative Evaluation of Caudal Dexmedetomidine and Caudal Ketamine as Adjuvants to Isobaric Bupivacaine for Postoperative Analgesia in Children Undergoing Surgery for Developmental Dysplasia of the Hip","CDK-DDH","Inclusion Criteria:\n\n* Children aged 1 to 6 years undergoing surgery for developmental dysplasia of the hip\n* ASA physical status I or II\n* Parental or guardian informed consent obtained\n\nExclusion Criteria:\n\n* Known allergy to local anesthetics, Dexmedetomidine, or Ketamine\n* Coagulopathy or bleeding disorders\n* Infection at the site of caudal injection\n* Neurological disorders\n* Severe systemic disease\n* Refusal of parental consent","1 Year","6 Years",{"count":120,"type":22},54,[94],"This study compares two medicines, Dexmedetomidine and Ketamine, added to caudal Bupivacaine to control pain after hip surgery in children. We will check how well each medicine reduces pain, how long the pain relief lasts, and if children need extra pain medicine. The goal is to find the safest and most effective option for postoperative pain relief in children undergoing hip surgery.",[27],[125],"Caudal block Dexmedetomidine Ketamine Pediatric analgesia Bupivacaine Postoperative pain Hip surgery DDH","2026-01-27",{"date":128,"type":44},"2026-02-04",{"date":130,"type":22},"2026-03-01",{"date":132,"type":22},"2026-09",{"name":134,"class":51},"Assiut University",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":142,"enrollmentInfo":143,"targetDuration":4,"studyType":64,"phases":145,"briefSummary":146,"conditions":147,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":52},"100506089","developmental-dysplasia-of-the-hip-observation-vs-bracing-100506089","NCT05869851","Developmental Dysplasia of the Hip: Observation vs. Bracing","Comparison of Brace to Observation in Stable, Radiological Developmental Dysplasia of the Hip: A Multi-centre, International Randomized Controlled Non-inferiority Trial","Inclusion Criteria:\n\n* Patients presenting with radiological dysplasia of a clinically stable hip under three months (12 weeks) of age\n* Radiological dysplasia will be defined as a centred hip with an alpha angle between 43 and 60 degrees and a percent coverage of the femoral head (FHC) greater than 35%, as measured on ultrasound exam\n\nExclusion Criteria:\n\n* Patients presenting with radiological dysplasia older than three months (12 weeks) of age\n* Patients presenting with clinical hip instability (Ortolani or Barlow positive)\n* Patients with known or suspected neuromuscular, collagen, chromosomal or lower-extremity congenital abnormalities or syndromic-associated hip abnormalities\n* Patients who received prior treatment (i.e. Pavlik harness) for DDH","12 Weeks",{"count":144,"type":22},514,[94],"Developmental dysplasia of the hip (DDH) is the most common childhood hip condition. When caught early, bracing is the most frequently used treatment; however, the brace can disrupt important mother-baby bonding time in the newborn period and present challenges to daily living. In babies with mild DDH, some studies have suggested that their hips may improve naturally as they grow and develop. This study will look at whether careful monitoring can be just as good as bracing for babies diagnosed with mild DDH less than 3 months of age, potentially avoiding unnecessary treatment. This will be the first study to look at this question with babies being treated at different hospitals in seven different countries, so the results will make an impact on children and families worldwide.",[27,148,149,150],"Hip Dysplasia","Hip Dysplasia, Congenital","Hip Dysplasia, Developmental","2025-11-19",{"date":153,"type":44},"2025-11-24",{"date":155,"type":44},"2024-04-25",{"date":157,"type":22},"2028-09",{"name":159,"class":51},"University of British Columbia",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":164,"acronym":4,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":168,"conditions":169,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":52},"100555470","prospective-cohort-study-of-arthroscopic-treatment-of-hip-dysplasia-100555470","NCT06512506","Prospective Cohort Study of Arthroscopic Treatment of Hip Dysplasia","Inclusion Criteria:\n\n\\- Diagnosis of borderline hip dysplasia with glenolabial injury.\n\nExclusion Criteria:\n\n\\-",{"count":167,"type":22},47,"On the basis of the database established in the previous stage, a cohort analysis was conducted on patients with BDDH complicated by hip arthroscopy for minimally invasive treatment of glenoid and lip injury, according to which the indications of minimally invasive surgery for BDDH patients were optimized and surgical measures were improved. Achieve accurate and rapid repair, rehabilitation and functional recovery, serve national fitness, and treat people's injuries",[27],"2024-07-16",{"date":172,"type":44},"2024-07-22",{"date":174,"type":44},"2022-01-01",{"date":176,"type":22},"2024-12-31",{"name":178,"class":51},"Peking University Third Hospital"]