[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diabetic-retinopathy-visually-threatening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diabetic-retinopathy-visually-threatening":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":5},"100558277","single-session-vs-multiple-session-panretinal-photocoagulation-for-treatment-of-proliferative-diabetic-retinopathy-100558277",false,"NCT06549023","Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy","Single Session vs Multiple-Session Panretinal Photocoagulation With Navigated Laser in Proliferative Diabetic Retinopathy - The SMART-PRP Study","SMART-PRP","Inclusion Criteria:\n\n* Age \\> 18 years.\n* Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.\n* Visual acuity ≥ 0.1 Snellen.\n* CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.\n* Clear media and adequately dilated pupil for PRP.\n\nExclusion Criteria:\n\n* Intraocular surgery within the last 4 months or planned within the next 3 months.\n* Previous or current center-involved diabetic macular edema (Ci-DME).\n* Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.\n* Treatment with medications known to risk macular edema.\n* Media opacity preventing adequate PRP.\n* General medical condition making office laser treatment very difficult or impossible.","ALL","18 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP). In current clinical practice, both single-session and multiple-session PRP approaches are widely accepted and utilized. The purpose of this study is to compare the safety and effectiveness of single-session and multiple-session PRP.",[27,28,29,30,31,32],"Proliferative Diabetic Retinopathy","Diabetic Retinopathy","Diabetic Retinopathy Visually Threatening","Diabetic Macular Edema","Diabetes Mellitus, Type 1","Diabetes Mellitus, Type 2",[34,35,36,37,38,39,40,41,42,43,44,45,46],"Panretinal photocoagulation (PRP)","Single-session PRP","Multiple-session PRP","Navigated laser","Navilas","Central subfield retinal thickness (CRT)","Macular volume","Optical coherence tomography (OCT)","Swept-source optical coherence tomography (SS-OCT)","Wide-field fundus imaging","OCT-angiography","Retinal oximetry","Electroretinogram (ERG)","RECRUITING","2025-11-17",{"date":50,"type":51},"2025-11-18","ACTUAL",{"date":53,"type":51},"2025-01-01",{"date":55,"type":21},"2030-12-31",{"name":57,"class":58},"Vastra Gotaland Region","OTHER_GOV"]