[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diagnostic-accuracy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diagnostic-accuracy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,88],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100629116","evaluation-of-one-shot-vision-differential-diagnosis-osvde-and-multi-step-conversational-non-inferiority-mscne-in-ai-medical-interviewing-100629116",false,"NCT07470463","Evaluation of One-Shot Vision Differential Diagnosis (OSVDE) and Multi-Step Conversational Non-Inferiority (MSCNE) in AI Medical Interviewing","AI Medical Interviewing and Diagnostic System Performance Evaluation: One-Shot Vision Differential Diagnosis (OSVDE) and Multi-Step Conversational Non-Inferiority (MSCNE) Evaluation.","OSVDE-MSCNE","Inclusion Criteria:\n\n* Active license in Dermatology, Internal Medicine, Otolaryngology, Gynecology, Orthopedics, Pediatrics, Geriatrics, Emergency Medicine, Ophthalmology, Psychiatry, Endocrinology, Family Medicine, or a closely related specialty\n* Age 18 years or older\n* Ability to complete diagnostic evaluation sessions remotely using a computer or tablet with reliable internet access\n\nExclusion Criteria:\n\n* Loss of active license in an eligible specialty\n* Inability to complete the evaluation session remotely",true,"ALL","18 Years",{"count":21,"type":22},30,"ESTIMATED","6 Months","OBSERVATIONAL","This study evaluates the diagnostic performance of a multimodal artificial intelligence (AI) system (AIMD.1) using de-identified medical images and semi-synthetic patient simulations. The study combines retrospective analysis of existing publicly available image datasets with prospective data collection from licensed clinicians who complete diagnostic evaluation tasks.\n\nIn the One-Shot Vision Differential Evaluation (OSVDE) stage, clinicians review individual de-identified medical images and generate a ranked list of potential diagnoses based solely on visual features. In the Multi-Step Conversational Non-Inferiority Evaluation (MSCNE) stage, clinicians complete diagnostic assessments using semi-synthetic patient simulations derived from de-identified medical images. Clinician performance will be compared with the AI system on the same diagnostic tasks.\n\nHuman participants consist solely of licensed clinicians who provide diagnostic responses. Medical images and simulated cases are study materials and are not considered study participants. No identifiable patient data are used, and the AI system is evaluated in an offline research environment and is not used for clinical decision-making or patient care.",[27,28],"Differential Diagnosis","Diagnostic Accuracy",[30,28,27,31,32,33,34,35,36,37],"Artificial Intelligence","Clinical Decision Support","Computer Vision","Medical Imaging","Multimodal AI","Physician Performance","Non-Inferiority","Diagnostic Reasoning","RECRUITING","2026-03-20",{"date":41,"type":42},"2026-03-25","ACTUAL",{"date":44,"type":42},"2026-03-19",{"date":46,"type":22},"2026-09-19",{"name":48,"class":49},"Magic Health Inc. (d.b.a. Nolla Health)","INDUSTRY",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":18,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":50},"100574589","comparing-fluorescent-starch-nanoparticles-rinse-with-icdas-for-early-caries-detection-in-children-100574589","NCT06761248","Comparing Fluorescent Starch Nanoparticles Rinse with ICDAS for Early Caries Detection in Children","Clinical Effectiveness of Fluorescent Starch Nanoparticles Caries Detection Rinse Versus International Caries Detection and Assessment System for Detection of Early Dental Caries in Children: a Diagnostic Accuracy Study","FSNCDR-ICDAS","Inclusion Criteria:\n\n* Children with active initial caries.\n* At least two teeth with active caries (ICDAS 1 or 2) and two teeth with inactive caries.\n\nExclusion Criteria:\n\n* Teeth with hypoplasia, fractures, or conditions like dentinogenesis imperfecta.\n* Children with fixed orthodontic appliances.\n* Participants whose guardians refuse consent.","6 Years","11 Years",{"count":62,"type":22},78,"INTERVENTIONAL",[65],"NA","The present study aims to evaluate the diagnostic accuracy of fluorescent starch nanoparticles caries detection rinse versus the International Caries Detection and Assessment System (ICDAS) in identifying early dental caries among children from 6 to 11 years old.",[68,69,70,28],"Dental Caries","Detection","Fluorescence",[72,73,74,75,76],"Fluorescence-Based Caries Detection","Caries Detection Rinse","Early Caries Detection","ICDAS","FSN","NOT_YET_RECRUITING","2024-12-31",{"date":80,"type":42},"2025-01-07",{"date":82,"type":22},"2025-03-10",{"date":84,"type":22},"2026-08-15",{"name":86,"class":87},"Cairo University","OTHER",{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":50},"100502100","diagnostic-accuracy-of-capnography-in-nasogastric-tube-placement-100502100","NCT05817864","Diagnostic Accuracy of Capnography in Nasogastric Tube Placement","Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings","Inclusion Criteria:\n\n* 18 years old or above;\n* Admitted to the general medical and geriatric wards, ICUs, or subacute\u002Frehabilitation\u002Finfirmary wards in subacute\u002Fconvalescent\u002Fextended care hospitals or visiting AEDs in acute hospitals;\n* Requiring the insertion of an nasogastric tube into the stomach for assessment, nutritional support and medication administration during the study period.\n\nExclusion Criteria:\n\n* Participants receiving life-saving intervention at the time of recruitment.",{"count":96,"type":22},390,"A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of using capnography in detecting the correct placement of nasogastric tubes using the reference standards of radiography and measurement of aspirates for pH value.",[99,100,28],"Capnography","Nasogastric Tube",[99,102,103],"Intubation, gastrointestinal","Diagnostic accuracy","2024-09-02",{"date":106,"type":42},"2024-09-05",{"date":108,"type":42},"2023-07-01",{"date":110,"type":22},"2025-12",{"name":112,"class":87},"Chinese University of Hong Kong"]