[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dietary-exposure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dietary-exposure":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,43,72,127,149],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100566327","phase-3-trial-to-assess-the-efficacy-of-empagliflozin-and-personalized-dietary-counseling-for-kidney-stone-prevention-100566327",false,"NCT06653738","Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention","Randomized Placebo-controlled Trial to Assess Efficacies of EMPAgliflozin and Personalized Dietary Counselling for Kidney STONE Prevention in Patients With Calcium Kidney Stones Acronym: EMPASTONE Trial","EMPASTONE","Inclusion criteria:\n\n1. Written, informed consent.\n2. Age 18 years or older.\n3. Recurrent kidney stone disease with 2 or more stone episodes in the last 10 years prior to randomization.\n4. Last kidney stone containing 50% or more of CaOx, CaP or a mixture of both.\n5. If taking guideline-recommended medications for kidney stone prophylaxis (e.g. citrate salts), patients must have been on a stable regimen for at least 60 days before randomization and willing to remain on this stable regimen for the duration of the study.\n\nExclusion criteria:\n\n1. Known history of secondary or Mendelian causes of calcium nephrolithiasis\n2. Type I diabetes mellitus\n3. History of ketoacidosis\n4. Chronic Kidney Disease (CKD) stage 4 or 5 (defined as CKD-EPI eGFR \\\u003C30 mL\u002Fmin)\n5. Kidney transplant recipient\n6. History of recurrent urinary tract infections, defined as \\>3 episodes within the year prior to randomization\n7. Heart failure. Symptomatic patients with suspected heart failure must be evaluated before study enrollment\n8. Treatment with an SGLT2i within 4 weeks prior to randomization.\n9. Active cancer treatment\n10. Pregnancy and\u002For breastfeeding. Women of childbearing potential (i.e., premenopausal women who have not undergone surgical sterilization and are sexually active with a male partner) must have a negative urine or blood pregnancy test prior to enrollment\n11. Known allergy to the study drug\n12. Inability to understand and follow the study procedures\n13. Vulnerable individual, e.g. individual incapable of judgement or currently incarcerated or otherwise institutionalized (priosner), or refugee\n14. Concomitant participation in another interventional clinical trial within 4 weeks prior to randomization and during the current trial\n15. Prior enrollment in the EMPASTONE trial","ALL","18 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","The aim of this randomized trial with a 2-by-2 factorial design is to test the efficacy of the SGLT2 inhibitor empagliflozin and personalized dietary counseling based on 24-hr urine collection results and dietary assessments for kidney stone recurrence prevention in patients with calcium kidney stones.\n\nStudy interventions:\n\n* Empagliflozin 10 mg once daily per os for 36 months\n* Personalized dietary counseling for 36 months.\n\nControl interventions:\n\n* Placebo once daily per os for 36 months\n* Generic dietary counseling for 36 months.",[27,28,29],"Kidney Stone","Nephrolithiasis","Dietary Exposure","NOT_YET_RECRUITING","2026-05-21",{"date":33,"type":34},"2026-05-27","ACTUAL",{"date":36,"type":21},"2026-06",{"date":38,"type":21},"2030-09",{"name":40,"class":41},"Insel Gruppe AG, University Hospital Bern","OTHER",21,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":17,"minAge":18,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100608548","tasting-plant-forward-meals-100608548","NCT07202988","Tasting Plant Forward Meals","Investigating the Role of Potatoes in Boosting Vegetable Enjoyment and Consumption Among Adolescents and Emerging Adults","Inclusion Criteria:\n\n* between the ages of 18-25 years\n\nExclusion Criteria:\n\n* unable to complete all study procedures\n* food allergies to any of the study food",true,"25 Years",{"count":53,"type":21},80,[55],"NA","This study aims to examine how the amount of potato and form of potato within a meal impacts intake and acceptability of other non-starchy vegetables.",[29],[59,60],"Diet Quality","Vegetable Intake","RECRUITING","2026-02-05",{"date":64,"type":34},"2026-02-10",{"date":66,"type":34},"2026-01-30",{"date":68,"type":21},"2026-12",{"name":70,"class":41},"Sara Maksi",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":93,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":126},"100540952","cohort-study-on-plant-based-diets-coplant-study-100540952","NCT06323538","Cohort Study on Plant-based Diets (COPLANT Study)","COPLANT","Inclusion Criteria:\n\n* age between 18 and 69 years at recruitment (age-stratified recruitment in four age groups (18 to 29, 30 to 39, 40 to 49 and 50 to 69 years) which should be equally distributed across the four diets)\n* following their current diet for at least one year\n* health insured\n* are willing to have blood taken (adults)\n* are willing and able to complete questionnaires\n* only at Berlin, Jena, Giessen and Karlsruhe sites: pregnant and breastfeeding women were recruited (shortened examination programm)\n* only at the Regensburg, Heidelberg, Bonn and Vienna sites: are neither pregnant nor breastfeeding at the time of recruitment\n* only at Berlin and Karlsruhe sites: children of adult participants (shortened examination programm without collection of blood, urine, and stool)\n* are able to give informed consent to participate in the study\n* have given their consent to participate in the COPLANT study\n\nExclusion Criteria:\n\n* who can no longer be contacted\n* who withdraw their consent to participate in the study","69 Years",{"count":81,"type":21},6000,"OBSERVATIONAL","The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria. The COPLANT study focuses on vegan (no animal products), vegetarian (no meat and fish, but dairy products and eggs), pescetarian (no meat, but fish) and omnivorous (mixed diet including all possible animal products) diets. The aim of the COPLANT study is to gain new insights on health benefits and risks as well as social, ecological and economic effects of different plant-based diets in comparison to a mixed diet. In addition to a detailed dietary survey using an app adapted to the needs of this study, the baseline examination includes measurements of body composition, bone health, cardiovascular risk factors, diabetes risk, contaminants and lifestyle. For the basic laboratory program, fasting blood, 24-hour urine collection and a stool sample are taken from all study participants. Furthermore, specific aspects of dietary behavior, physical activity and other lifestyle factors are collected via questionnaires. Follow-up studies are planned at intervals of 5, 10 and 20 years after the baseline visit.",[29,85,86,87,88,89,90,91,92],"Diabetes Mellitus, Type 2","Cardiovascular Diseases","Bone Loss","Sustainability","Exposure","Obesity","Vitamin Deficiency","Mineral Deficiency",[94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116],"vegan","vegetarian","pescetarian","omnivor","multicenter cohort","biomarker","vitamins","minerals","bone health","cardiovascular risk","body composition","inflammation","contaminants","diabetes type 2","thyroid gland health","microbiota","metabolomics","adults","children","pregnancy","breast feeding time","mental health","sustainability","2025-02-13",{"date":119,"type":34},"2025-02-14",{"date":121,"type":34},"2024-04-09",{"date":123,"type":21},"2047-03-31",{"name":125,"class":41},"German Federal Institute for Risk Assessment",8,{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":50,"sex":17,"minAge":18,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":71},"100551405","the-bowel-movement-monitoring-bomomo-study-100551405","NCT06459661","The Bowel Movement Monitoring (BoMoMo) Study","The Bowel Movement Monitoring (BoMoMo) Study: An Exploration of the Relationship Between Intake of Unrefined, Intact Plant Foods and Faecal Output","BoMoMo","Inclusion Criteria:\n\n* Age: 18-60 years.\n* Healthy as determined from self-reported medical history or when no relevant medical condition exists.\n* Stool frequency of 3 to 21 times per week.\n* Able to attend a session in person at City Campus or Headingley Campus, Leeds Beckett University, or City Campus, Sheffield Hallam University.\n* For women: Use of contraceptive methods or not planning to become pregnant for the duration of the study.\n* Able to understand and be willing to sign the informed consent form, and to follow all the study procedures and requirements.\n\nExclusion Criteria:\n\n* Food allergy or intolerance\n* Currently dieting to lose weight\n* For women: Pregnancy, lactation\n* Bowel disease\n* Use of medicine causing constipation\n* Abnormal gastro-intestinal (gut) function or structure such as malformation, angiodysplasia or active peptic ulcer\n* History of gastro-intestinal surgery with permanent effect (e.g., surgical treatment of obesity)\n* Active inflammatory bowel disease, coeliac disease, chronic pancreatitis, or other disorder potentially causing malabsorption\n* Currently experiencing or been diagnosed with gastro-intestinal symptoms (e.g., abdominal pain\u002Fcramps, heartburn, stomach acid\u002Freflux, nausea, vomiting, abdominal rumbling, bloating, belching, excess gas\u002Fwind)\n* Active constipation (i.e., currently constipated).\n* Active Irritable Bowel Syndrome\n* Currently experiencing disordered eating\n* Current use of laxatives\n* Current use or within the previous 3 months use of prescription or over-the-counter medication that has the potential of affecting gut bacteria including food supplements (specific medications will be assessed on an individual basis).\n* Use of antibiotics or pain medication containing opiates or morphine currently or within the previous 3 months.\n* Use of opioid drugs of abuse (e.g., heroin, fentanyl) currently or within the previous 3 months.\n* Consumption of more than 21 units of alcohol per week (men)\u002F more than 14 unit of alcohol per week (women).\n* Malignancy\u002Fcancer which is currently active or in remission for less than 2 years after treatment.\n* Currently experiencing a psychiatric disorder or a condition related with your mental health that impacts on your daily life (e.g., major depression, bipolar disorders).\n* Currently engaging in intense physical activity more than 3 times per week (assessed on an individual basis).\n* Presenting a psychological or linguistic incapability to sign the informed consent\u002F Investigator considers the subject unlikely to comply with study procedures, restrictions, and requirements.\n* Parallel participation in another research project which involves dietary intervention\u002Fother clinical trial.","60 Years",{"count":137,"type":21},24,"The link between what people eat and how it affects faecal output (poo) has been understudied. Most of the research that has looked at the link between diet, bowel movements and overall health has studied different types of fibre extracted from foods (e.g., fibre extracted from carrots), rather than foods in the form that they are consumed.\n\nIt is necessary for scientists to investigate the relationship between food as people usual eat it (e.g., a carrot) and bowel movements, as this information is key to understanding the relationship between what people eat and overall health.\n\nThe investigators would like to understand the relationship between intake of certain foods and faecal output. This will help to develop a chart, similar to the United Kingdom National Health Service urine colour hydration chart. The chart will allow people to know, by looking at their poo, whether they are eating enough of the foods that will keep them healthy. By monitoring and measuring participants' bowel movements, and providing information about diet, participants will provide the data we need for this research.",[29],"2024-06-14",{"date":142,"type":34},"2024-06-17",{"date":144,"type":34},"2024-05-01",{"date":146,"type":21},"2024-06-30",{"name":148,"class":41},"Leeds Beckett University",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":156,"minAge":18,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":159,"conditions":160,"keywords":164,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":4},"100519680","diet-quality-of-pregnant-women-with-a-strict-plant-based-diet-versus-an-omnivorous-diet-100519680","NCT06046703","Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous Diet","Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous Diet: a Focus on Vitamin B12 Intake and Other Nutritional and Pregnancy-related Outcomes","Inclusion Criteria:\n\n* Before 27 weeks of pregnancy\n* Age \\>18 years\n* Strict plant-based diet (vegan diet), defined as a diet without ingestion of animal products (i.e., intake less than once a month during) the entire pregnancy or omnivorous diet, defined as a diet that includes meat\n* Willing and able to give written informed consent and to understand, participate and comply with the research project requirements\n\nExclusion Criteria:\n\n* Food allergy that influences the nutritional intake, e.g., milk allergy, celiac disease, and lactose intolerance\n* Medical history of gastrointestinal diseases such as Crohn's disease and other diseases associated with vitamin B12 deficiencies such as (pre-existing) diabetes.\n* Medical history of abdominal surgery interfering with nutrient uptake, such as gastric bypass and intestinal resections\n* Pre-existing cardio-vascular diseases or auto-immune diseases\n* Insufficient understanding of the Dutch language","FEMALE",{"count":158,"type":21},256,"The goal of this observational study is to compare the nutritional intake among pregnant women with a strict plant-based diet versus an omnivorous diet.\n\nThe main aim is to compare vitamin B12 intake.\n\nParticipants will be asked to:\n\n* fill out a health questionnaire\n* fill out a three-day food diary\n* undergo blood sampling Researchers will compare pregnant women with a strict plant-based diet and pregnant women with an omnivorous diet to see if their nutritional intake is comparable.",[161,162,163,29],"Vitamin B 12 Deficiency","Pregnancy","Nutrient Deficiency",[165,113,166,167,168],"vegan diet","vitamin b12","omnivorous","nutrition","2024-03-12",{"date":171,"type":34},"2024-03-13",{"date":173,"type":21},"2025-01-01",{"date":175,"type":21},"2027-07-01",{"name":177,"class":41},"Maastricht University Medical Center"]